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🧬 PAPA Syndrome: When Sterile Inflammation Mimics Infection

(Pyogenic Arthritis, Pyoderma gangrenosum, Acne)

•A r

Ravi Kumar RheumattDoc

6 months ago
🧬 PAPA Syndrome: When Sterile Inflammation Mimics Infection (Pyogenic Arthritis, Pyoderma gangrenosum, Acne) •A rare monogenic autoinflammatory disease •Caused by gain-of-function mutations in PSTPIP1 🧠 Pathophysiology •Mutant PSTPIP1 → increased interaction with pyrin https://t.co/tJ4INdgfky
Rheum Poll> Which is the most difficult to treat RA (D2TRA) patient (despite aggressive Rx)?

Dr. John Cush RheumNow

6 months ago
Rheum Poll> Which is the most difficult to treat RA (D2TRA) patient (despite aggressive Rx)?
BIOBADASER III Registry shows No Cancer Risk with b/tsDMARDs

A large, real-world cohort study of rheumatoid arthritis

Dr. John Cush RheumNow

6 months ago
BIOBADASER III Registry shows No Cancer Risk with b/tsDMARDs A large, real-world cohort study of rheumatoid arthritis (RA) finds patients treated with biologic and targeted synthetic DMARDs (b/tsDMARDs) do not have an increased risk of cancer. https://t.co/0oawv88Anq https://t.co/nrsok06gKV
Kick off 2026 with #RheumNowLive—two days of cutting-edge rheumatology, rapid-fire STEP talks, interactive Q&A, an

Aurelie Najm AurelieRheumo

6 months ago
Kick off 2026 with #RheumNowLive—two days of cutting-edge rheumatology, rapid-fire STEP talks, interactive Q&A, and real-world insights with Drs. Jack Cush, Arthur Kavanaugh, and a powerhouse faculty. Register: https://t.co/zh0aBDMfoP @RheumNow
APPIPRA Study - Benefits of Early Treatment

Treating people who are at high risk of rheumatoid arthritis (RA) can dela

Dr. John Cush RheumNow

6 months ago
APPIPRA Study - Benefits of Early Treatment Treating people who are at high risk of rheumatoid arthritis (RA) can delay the onset of the disease for several years, with benefits also continuing well after treatment has stopped. https://t.co/hgxj936CWn https://t.co/eJX3amp3Id
A recent study examines trends in rheumatoid arthritis (RA)-related mortality among U.S. postmenopausal women (aged 55 and older). They found RA mortality rates have declined, yet disparities in who is most affected persist, especially for white women, and those over 85 yrs of age.
Turkish study of 128 Psoriatics (62 PSO, 66 PsA) found more periodontitis in PsA vs PSO (47% vs 31%; P=.058). Signif. hi

Dr. John Cush RheumNow

6 months ago
Turkish study of 128 Psoriatics (62 PSO, 66 PsA) found more periodontitis in PsA vs PSO (47% vs 31%; P=.058). Signif. higher levels of Dz activity seen for PSO (CPDAI: OR 1.38; P = .001) & enthesitis (MASES: OR 1.39; P < .001) if periodontitis present in PsA patients. https://t.co/d8OfarFWeG
“We will remember not the words of our enemies, but the silence of our friends.”
- Martin Luther King, Jr.

Dr. John Cush RheumNow

6 months 1 week ago
“We will remember not the words of our enemies, but the silence of our friends.” - Martin Luther King, Jr.
Drugs that may cause toxic myopathy, presenting as muscle dysfunction w/ weakness and elevated muscle enzymes and possib

Dr. John Cush RheumNow

6 months 1 week ago
Drugs that may cause toxic myopathy, presenting as muscle dysfunction w/ weakness and elevated muscle enzymes and possibly confused w/ idiopathic inflammatory myopathies (IIM) - full read review of mimickers of myositis. https://t.co/1Yn3OXXEH6 https://t.co/HmQiYFSQMU
Subcutaneous Anifrolumab in SLE

Manzi et al. have published the results of the TULIP-SC trial that showed that weekly

Dr. John Cush RheumNow

6 months 1 week ago
Subcutaneous Anifrolumab in SLE Manzi et al. have published the results of the TULIP-SC trial that showed that weekly subcutaneous (SC) anifrolumab, when given to severe SLE patients, had comparable efficacy and safety to the approved intravenous (IV) anifrolumab. https://t.co/EzaqS5q096
The 2025 Rheumatology Year in Review

The year 2025 presented numerous advances in rheumatology and related inflammator

Dr. John Cush RheumNow

6 months 1 week ago
The 2025 Rheumatology Year in Review The year 2025 presented numerous advances in rheumatology and related inflammatory and autoimmune disorders, ranging from several new groundbreaking FDA approvals/indications, drug developments, game-changing guidelines, and practices that https://t.co/71stL3X8my
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