David Liew drdavidliew
4 years 10 months ago
I've written more about these really useful data here for @RheumNow:
https://t.co/3dQteFr9qZ
#ACR21 @earlyarthritis @BykerkVivian https://t.co/7HufoWVtCK
Pedro Castillo _Castillo_Pedro
4 years 10 months ago
AURORA 2 (A2): SLE + LN
AURORA 1: Adding Voclosporin to MMF + Steroids ⬆️complete renal response by 18% @ 52w
A2: @ 30 months
💠Maintained mean GFR
💠Maintained reductions in proteinuria
💠Further safety/efficacy data to follow
https://t.co/wSvQvueKi7
#ACR2021 Abst#1425 @RheumNow
TheDaoIndex KDAO2011
4 years 10 months ago
Median survival for pts w/#VEXAS➡️10 years
Predictors of mortality w/VEXAS:
👉p.MetVal mutation HR 3.5 (95%CI, 1.4-8.5)
👉transfusion dependency HR 2.59 (95%CI, 0.94-7.09)
👉⬇️risk w/ear chondritis HR 0.26 (95%CI,0.09-0.6)
@marcelaferrada #ACR21 @rheumnow Abstr#1426 #ACRbest
Dr. John Cush RheumNow
4 years 10 months ago
Plenary on VEXAS - good over view of VEXAS and why important to Rheums #ACR21 Abstract# 1426 https://t.co/jx0mQNlfwK
Dr. John Cush RheumNow
4 years 10 months ago
SLE Panel: Learning about Lupus at #ACR21
Drs. Kathryn Dao ( @KDAO2011) , Janet Pope ( @Janetbirdope) Yuz Yusof ( @Yuz6Yusof) Bella Mehta ( @bella_mehta) and Pedro Castillo ( @_Castillo_Pedro) discuss lupus-related data presented Saturday.
https://t.co/h0vPIwUeOz https://t.co/eJDtRKPdYT
Meral K. El Ramahi, MD MeralElRamahiMD
4 years 10 months ago
Clinical Pearl from Dr. @JKolfenbach
"Sometimes, taking off the mask is worth it" during physical exam:
➡️Strawberry gums in GPA
➡️Drug-induced gingival hyperplasia
‣ i.e. cyclosporine, CCB
➡️Tongue necrosis in GCA
➡️Ovoidal palatal patch in TIF1gamma DM
#ACR21 @RheumNow https://t.co/H98bTLLse6
Meral K. El Ramahi, MD MeralElRamahiMD
4 years 10 months ago
Wonderful overview of myositis autoantibodies to reference from the Rheum Secrets & Pearls session by Dr. @JKolfenbach & Dr. John Stone at #ACR21 that can be accessed on-demand now!
@RheumNow https://t.co/H6N02MzFSu
Md Yuzaiful Md Yusof Yuz6Yusof
4 years 10 months ago
#ACR21 #Abstr1423 Munroe & James developed a novel #Lupus Classification Risk Immune Index using either 9 or 32 soluble mediators from sera. This index could predict transition to meeting classification criteria (with or without autoantibodies) @RheumNow https://t.co/Kr9fWaoW1L https://t.co/8wkgrzeRnt
Dr. Rachel Tate uptoTate
4 years 10 months ago
Spanish study finds OP is more frequent in male PsA pts, assoc'd w/age independent of dz hx. Femoral OP more frequent in pts w/ axial involvement, HTN, heart ischemic disease & vitamin D deficiency. Abs 1325 #ACR21 #RheumNow #ACRbest @RheumNow https://t.co/A3v6ZHZnN8 https://t.co/2jfAOSuLtK
Bella Mehta bella_mehta
4 years 10 months ago
We @HSpecialSurgery previously demonstrated improved fetal mortality in #lupus in @AnnalsofIM
Racial disparities persist ~61K #lupus pregnancies - 10 yr US national data #abst1034 at #ACR21 more reduction in Asians and Hispanics than African Americans @RheumNow https://t.co/KeO0FdMB7f
Olga Petryna DrPetryna
4 years 10 months ago
Abst1314 #acr21 @RheumNow factors associated w/ Acute anterior uveitis in AxSpA:
-history of AAU
-male gender
- presence of extraspinal involvement
-concomitant cs-DMARD usage
-BASDAI scores ASDAS-CRP, and PGA of disease activity. https://t.co/4YA8dSJzy3
Dr. Antoni Chan synovialjoints
4 years 10 months ago
Raised BMI is related to poorer outcomes to biologics in PsA. The mean change in outcome measures (cDAPSA, RAPID3, PsAID) was lowest among obese patients . This was observed primarily among TNFi initiators vs to OSM or IL17i @RheumNow #ACR21 Abstr#1327 https://t.co/pm7PPp9UH4 https://t.co/j5GWpCBD2d
Dr. Rachel Tate uptoTate
4 years 10 months ago
Real-world PsA study: MDA assoc'd w/ higher probability of achieving clinically meaningful improvements in dz activity & PROMs. MDA pts more likely w/ b/tsDMARDs, but found in less than 25% of pts in COREVITAS cohort. Abs 1344 #ACR21 #RheumNow @RheumNow
https://t.co/RrAfXvn4kf https://t.co/TjPCwzYfZK
David Liew drdavidliew
4 years 10 months ago
How does @US_FDA see Tyk2 inh: part of or separate to JAKi class?
“I don’t think I’m in a position to make a call on this at this meeting, but certainly Tyk2 is a JAK”
Tantalising end to a great session at #ACR21. Feels like the audience could have questions for days. @RheumNow
Eric Dein ericdeinmd
4 years 10 months ago
#ACR21 plenary#1424. JUNIPERA study for Secukinumab for ERA, JPsA
⭐️Time to disease flare longer in SEC vs PBO
⭐️Sustained improvement up to wk 104
▶️Rapid decrease of JADAS-27 in initial open-label portion of study
https://t.co/m5bl9Ho163 @Rheumnow https://t.co/wnEdxeYfjh

