Eric Dein ericdeinmd
4 years 10 months ago
#ACR21 Abs#1225: B/L Extracell Matrix Biomarkers predict ABA response in MTX-naive, +ACPA early RA
⭐️ECM biomarkers predict SDAI remission or DAS28 w ABA+MTX vs PBO+MTX.
⭐️⬆️CTX1 biomarker predicts efficacy endpts for ABA+MTX
https://t.co/7wHQefb5D4 @Rheumnow
Mrinalini Dey DrMiniDey
4 years 10 months ago
Wk 12 disease activity predicts wk 24/26 remission/low disease activity with #upadacitinib 15mg in MTX-naïve or inadequate responders to MTX and/or TNFi pts.
≥50% improvement in SJC/TJC at Wk 12 was assoc with wk 24/26 remission/low disease activity.
Abs#1237 #ACR21 @RheumNow https://t.co/PAaCe5MAcu
Eric Dein ericdeinmd
4 years 10 months ago
#ACR21 - Starting soon - The Gift of Gab! with @BayviewMedicine @jhrheumatology Jason Liebowitz moderating Communication for the Physician with @Wharton Janet Zeide. Learn about the RHEUM acronym for speaking! @Rheumnow https://t.co/wcgFUBcZeX
Dr. Antoni Chan synovialjoints
4 years 10 months ago
EULAR update on vaccines. HZ vaccine safe with csDMARDs and TNFα blockers. Reduced cell immune response after 1 year. Assess Varicella Abs if exposure unknown. Non-live recombinant subunit adjuvant zoster vaccine may be a game changer @RheumNow #ACR21 8M101 https://t.co/PTLqYGRIGf
TheDaoIndex KDAO2011
4 years 10 months ago
Innovative!
Self-home fetal heart rate monitoring by the mother is feasible, accurate, effective for those with +anti-Ro/SSA Ab.
The study is still recruiting https://t.co/9BFihsgW5A Abst#1464 #ACR21 @rheumnow
https://t.co/ggmOpSGdZk
Dr. John Cush RheumNow
4 years 10 months ago
RheumNow’s expanded coverage of #ACR21 is sponsored in part by @Novartis. All content chosen by RheumNow & its Faculty.
Mrinalini Dey DrMiniDey
4 years 10 months ago
Abs#1036: illness-related uncertainty significantly correlates with #depression, #anxiety, and sickness impact in patients with autoimmune #rheumaticdiseases.
Particularly strong associations with #AAV and #SSc.
#MentalHealth #ACR21 @RheumNow
https://t.co/SiV9fst3Bh https://t.co/w8VRQHdAJC
Aurelie Najm AurelieRheumo
4 years 10 months ago
⚡️A new biomarker of structural progression in RA? Plasma levels of CXCL13 ⬆️ @ baseline vs. ctrl and ⬇️ (p< 0.0001) after 1 yr treatment in a eRA cohort. Levels above 85pg/ml ⬆️ x5 risk of > severe radiographic status at 11yrs. @RheumNow #ACR21 #Abst1204 https://t.co/LnkayR1YrY https://t.co/W0xsgGuUDW
Eric Dein ericdeinmd
4 years 10 months ago
#ACR21 Abst#1204. CXCL13 predicts long-term radiographic status in early RA
▶️ early RA has ⬆️ CXCL13, and ⬇️ w treatment
⭐️CXCL13 was best predictor of long-term radiographic destruction - better than DAS28CRP and CRP
@Rheumnow https://t.co/ydYRbKMBZ2 https://t.co/qinEFb86Az
Robert B Chao, MD doctorRBC
4 years 10 months ago
Increased risk of vertebral fractures in PsA pts
OR 2.09 from meta-analysis and systematic review
Abs#1304
#ACR21
@RheumNow
https://t.co/0IazVBGHsF https://t.co/YrPMh1TZ6U
Eric Dein ericdeinmd
4 years 10 months ago
#ACR21 Abst#1229: Does BMI influence efficacy of SC (fixed dose) vs IV (body-wt adjusted) ABA in RA?
⭐️No difference between SC and IV ABA by BMI
⭐️BMI impacts response to ABA as >2nd line therapy and retention, but no difference bw dosing
https://t.co/LqfZvLhBzU @Rheumnow
Mrinalini Dey DrMiniDey
4 years 10 months ago
Is #calprotectin the new ESR/CRP?
👉🏼SLR finds calprotectin correlates w/ ultrasound synovitis in RA
👉🏼In some studies, it was a better biomarker than ESR/CRP
👉🏼It can distinguish ultrasound remission from subclinical synovitis
Abs#1207 #ACR21 @RheumNow
https://t.co/ADkRBq5KoG
Aurelie Najm AurelieRheumo
4 years 10 months ago
CATCH cohort: PT CDAI and MD CDAI correlate good to strongly at 3 and 6mo in patients with no non articular pain or w/regional pain but 🚨 NOT in pts w/ widespread pain! We should find alternative remote DA measures for this pop. #ACR21 @RheumNow #Abst1202 https://t.co/LsCtsfXsN1 https://t.co/gjeGxBA0HB
Mrinalini Dey DrMiniDey
4 years 10 months ago
My video summary on this important piece of work by @Sineadm15 is now available to watch on @RheumNow:
https://t.co/Gh64D4PADw
#ACR21 #MentalHealth #Depression #AxSpA https://t.co/EcH4VDs2Xi

