With Deucravacitinib, a TYK2 inhibitor vs placebo, PsAID-12 and PsAID-9 scores were significantly improved versus baseline at Week 16 and other PROs showing a clear improvement in PsA-related impact @RheumNow #ACR21 Abst#0750 https://t.co/JbeSE2dO94 https://t.co/pH79dXCYSs

• Effect of Deucravacitinib on the Psoriatic Arthritis Impact of Disease Question…

SEC reduced SIJ bone marrow edema in active nr-axSpA pts. Majority of pts both in SEC and PBO arms showed no radiographic progression through 2 years. Abs 0921 #ACR21 #RheumNow @RheumNow https://t.co/yC2AZoacxF https://t.co/pjCL8HCanR

• Effect of Secukinumab on Radiographic Progression and Inflammation in Sacroilia…

#ACR21 #Abstr0864 How does obesity (BMI=/>30) affect #lupus outcomes? Data from Toronto showed: 💠⬆️hs-CRP 💠No in disease activity over 3yrs 💠⬆️CV events (combination of low grade inflammation + hypertension) @RheumNow https://t.co/IBu8uNSAJi https://t.co/2aqz5e3rwi

• Does Obesity Affect Disease Activity Outcomes in Systemic Lupus Erythematosus? …

Googling rheumatic diseases. On average google search lacked essential information to guide patient decisions. Websites on AS scored the highest on the DISCERN and RA scored the highest on JAMA @RheumNow #ACR21 Abst#0742 https://t.co/k2o2AqYEeh https://t.co/ZKljvA2f4O

• Googling Rheumatic Diseases: Evaluating the Reliability of Information Found on…

Can patient with low dx activity SLE stop HCQ, or at least try and reduce the dose? Not if you want to avoid flares. If there are safer subgroups to try it in, we haven't found them yet (in fact higher dx activity➡️less risk ?other Rx) SLICC inception #ACR21 ABST0959 @RheumNow https://t.co/NS2V4dEGHv

Let's look at MI first. Well, the numbers don't look great for tofa here. fatal MI very small numbers non-fatal MI - well that doesn't look good (do we have combined both tofa doses vs TNFi?) HR > 2 seems less than ideal - this would represent a substantial RF #ACR21 @RheumNow https://t.co/5HSXFrMJCu

🌞😎🍣 Vitamin D and Omega-3 FA ⬇️ Risk of developing autoimmune disease 1st prospective, randomized, double blind, placebo controlled trial Vit D 2000IU and/or Omega 3-FA 1000mg ⬇️autoimmune disease by 25-30% #ACR21 #ACRBest @RheumNow Abs#957 https://t.co/7dODuplg7e https://t.co/GUKhYXbSXU

• Vitamin D and Marine n-3 Fatty Acid Supplementation and Prevention of Autoimmun…

ORAL Surveillance: MACE events higher in TOFA vs TNFi. Independent risk factors: smoking, aspirin use, age ≥ 65 yrs, and male sex; TOFA vs TNFi tx in these pts assoc'd w/ numerically higher MACE incidence. Plenary Abs 0958 #ACR21 #ACRbest @RheumNow https://t.co/44af1KujqP

• Risk Factors for Major Adverse Cardiovascular Events in Patients Aged ≥ 50 Year…

Keep the Hydroxychloroquine! SLICC cohort eval flare risk in 1460 pts who⬇️or d/c HCQ: 👉pts in remission who d/c HCQ flared HR 2.77 (1.46,5.26) 👉pts in remission who⬇️dose flared HR 2.14 (1.34, 3.42) Abst#0959 #Plenary #ACR21 @rheumnow #ACRbest https://t.co/92U215s8IP

Controversial from John Stone at #ACR21 . Any thoughts @docrota @drhectorchinoy ? @RheumNow https://t.co/vBnolnQ7WV

Do you order EKGs in everyone starting HCQ? Do you avoid HCQ in patients with heart failure? Will these abstracts impact your practice? Click on link to read more....#ACR21 @rheumnow #HCQ https://t.co/fvUZAvNWa8

• Dr. John Cush on Twitter: "Prolonging the Controversy of Hydroxychloroquin…

Clinical Pearl at #ACR21 from Dr. J. Stone: ⭐️Tissue biopsy is not essential in diagnosing IgG4-related dz in a pt w/ a typical pattern of retroperitoneal fibrosis. ⭐️Periaortitis ("coated" aorta) w/ "hairy" kidney is NOT IgG4 but rather Erdheim-Chester Dz #ACRBest @Rheumnow https://t.co/2tB9p3c7W7

Abstr 0584 Patients in GLORIA Study noted to have - High number of comorbidities (median 6) - Multiple medications notably HTN and GI protection Findings represent medical reality of elderly RA patients (>65 years old) #ACR21 @RheumNow https://t.co/2cOtO9MLNM

• High Number of Comorbidities and Concomitant Medications at Baseline in the Glu…

#ACR21 #Abstr0858 Petri reported effect of #COVID and vaccination in #lupus cohort 💠No increase in activity post-infection 💠⬇️cutaneous activity 💠⬆️ aCL IgG and IgM post-infection, 💠No increase in SLE activity or aCL abs post-vaccination @RheumNow https://t.co/iAaIfzf33c https://t.co/hA6sk6icrs

• Effect of COVID Infection and COVID Vaccination on SLE Activity, Including Anti…

CARRA STOP-JIA 400pts, Obs study w/ 3 treatments plans : -Step up -Early combination -Biologic first Which one do you think works best? I'd say none: overall 40-60% not achieving CDI off steroids at 24 months. Results: 42% for SU, 52% EC, and 44% BF #Abtr0960 #ACR21 @RheumNow