RheumNow’s expanded coverage of the #ACR21 meeting is sponsored in part by @Novartis. All content chosen by RheumNow & its Faculty.

👉 anti-CK Ab may be a cause of #LongCovid syndrome 👉found in patients with autoimmune (SLE/Sjogrens) and can affect dz severity. 👉has not been seen in children 2/2 #ACR21

Role of anti-CK antibodies: 👉⬆️susceptibility to severe mycobacterial dz & opportunistic infx (similar to HIV) 👉causes an indeterminate quantiferon (no response to mitogen) 👉initiated by infx➡️anti-Noc2 Ab➡️cross react with IFN➡️IFN-Ab 👉⬆️severity of #COVID19 #ACR21 1/2 https://t.co/5NHQpwQw6X

“At the end of the day, the one treatment that will save the most lives will be the vaccines. That’s the homerun!” – Dr. R Cron, pediatric rheumatologist on reviewing treatments for hyperinflammation and #COVID19 @UABRheum #ACR21 #VaccinateOurKids https://t.co/dL1buLkMkM

In case you missed it. @ACRheum #COVIDvaccine guidance v 4.0 for Rheum patients & what's added: 👉3rd dose recommend, timing relative to meds (as before) 👉mRNA booster preferred if initial doses were mRNA 👉mAb as PrEP/Rx for high risk pts https://t.co/R8K8WeZBMt

• https://www.rheumatology.org/Portals/0/Files/COVID-19-Vaccine-Clinical-Guidance…

answer: CPPD. 👉CPPD can look like OA but can be more aggressive. 👉Look for chondrocalcinosis at the triangular ligament, pubic symphyis, superiolateral femoral head 👉A common cause of scapholunate widening 👉CPPD loves the patellofemoral joint (knee joint may be spared) https://t.co/wgYjJwYvb0

DECT (dual energy CT) very helpful to distinguish gout from other crystals and give volumetric measurements using color-coded images... So do we need to do arthrocentesis to diagnose gout anymore? #ACR21 https://t.co/kn2IpXP870

Pearls on gout: 👉Gouty tophi can appear in the L spine and destroy the facet joints #ACR21 Radiology Bootcamp with Dr. Brindle. https://t.co/ml2uI9f10v

Ouch! Patients with AS can fracture with minor trauma #ACR21 Radiology Bootcamp https://t.co/1piKvKUM2w

#ACR21 Radiology Bootcamp-- pretty helpful if you're studying for #ABIMRheumBoards Do you know how to distinguish sacroiliitis from pseudo-sacroiliitis? https://t.co/btS8mm8yH8

👉Get contrast if ordering an MRI to eval for inflamm. arthritis 👉Heel spur vs. enthesitis? Look for erosions at dorsum of calcaneus & other signs of inflamm 👉DISH vs. axial PsA? DISH➡️contiguous bony ossific'n up anterior margin of the vertebral bodies; PsA not cont.

Delighted to be reporting for @RheumNow from #ACR21 with @KDAO2011 @Yuz6Yusof @drdavidliew @Janetbirdope @uptoTate @AurelieRheumo @ericdeinmd @doctorRBC @synovialjoints @MeralElRamahiMD @DrMiniDey @_Castillo_Pedro @DrPetryna @AkhilSoodMD @swethaann23 @RHEUMarampa Follow them all!

The future according to Dr. M Brenner? 👉Bioengineered cells to treat inflammation.👈 #BasicScience #YearInReview #ACR21 @rheumnow https://t.co/EgoYBEZgT0

#GreatDebate: add belimumab (BLMB) vs. voclosporin (VCS) to MMF for lupus nephritis (LN) Dr. Petri argues for BLMB b/c: (1/2) 👉improvement in LN 👉improvement in non-renal lupus 👉decrease lupus renal mortality 👉**prevent GFR reduction ** 👉long term efficacy #ACR21 @rheumnow

KEEPsAKE trial 1 (DMARD-IR) and 2 (DMARD/biologic-IR) on risankizumab (IL23i) for PsA: 👉some benefits of risankizumab for axial disease 👉no data regarding bowel disease 👉pts did remain on background DMARDS, steroids. (2/2)