#ClinicalPearl What lasts longer/⬆️retention in sero+ RA: Abatacept or TNFi or JAKi? #ACR21 abst#0463 @RheumNow Adjusting for confounding incl line of Rx / past bio Rx, #abatacept wins. But data not stratified for bio naive or exposed. Not sure if that would alter results https://t.co/1dEQncwPQF

The best overall winner for the #ACR21 image competition https://t.co/Kr9EVAYVip

#ACR21 #ACR2021 #ACRLive wonderful slide set to explain the spinal phytes https://t.co/5SxN7GeDzh

#ACR21 Convergence Begins! Tune into our latest podcast where Dr. Cush reviews the news, and kicks off ACR21 learning and how to take in the annual meeting. https://t.co/UnFiUR91vB https://t.co/NxVzeQbP4H

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Factors that predict trajectories of radiographic progression in #axialspondyloarthritis 4 major patterns in the PSOAS cohort. Male gender, longer disease duration, raised CRP and smoking associated with higher spinal progression @RheumNow #ACR21 Abst#450 https://t.co/PvDE7T0MZp

• Identifying Trajectories of Radiographic Spinal Disease in Ankylosing Spondylit…

Abst 0450 #ACR21 @RheumNow PSOAS cohort 4 trajectories of radiographic progression in AS: Non-progressors 37%, late-progressors 26%, early-progressors 19%, rapid-progressors 18%.⬆️ disease burden: male, longer disease duration & smoking . ⬆️eCRP=higher disease progression https://t.co/wUdBNzJPy0

Abst 0452 #ACR21 #acrbest @RheumNow TB-PET/CT in PsA helps differentiate from RA/OA &measure inflammatory burden. Main findings asymmetric synovitis,systemic enthesitis, DIP& extensor tendons inflammation& adjacent nail matrix inflammation, Sacroiliitis& diffuse spine enthesitis https://t.co/7nTSIbmKfE

ASRI data: high frequency of pregnancy and fetal complications (miscarriage, c-section, early delivery, NICU admission) in AxSpA pts. We need more studies regarding risks/tx/outcomes/breastfeeding guidance. Abs 0369 #ACR21 #RheumNow @RheumNow https://t.co/4BR2ZPPjyB https://t.co/qyTwtfEMMy

• High Frequency of Complications in Axial Spondyloarthropathy Pregnancies: Emerg…

#ClinicalPearl Leflunomide for chronic CMV retinitis failing antiviral Rx? Suppresses inflammation & Arava May have antiviral properties. Didn’t know it. Kolfenbach & Palestine 6S117 eye opening experiences #ACR21 @RheumNow

What increases risk of RA-assoc #bronchiectasis, separate from #RA-ILD? Results from @BrighamResearch find seropositivity (esp high +ve RF/CCP), older age, disease duration, & low BMI incr. risk of isolated bronchiectasis in RA. #ACR21 Abs#0288 @RheumNow https://t.co/jvvRucqTjL https://t.co/aFCfxrbUdV

• Demographic, Lifestyle, and Clinical Risk Factors for Rheumatoid Arthritis-Asso…

Dr. Petri et al showed transition between lupus anticoagulant (-) to (+), (+) to (-), and (+) or (-) to thrombosis could be estimated by multistate Markov model. #ACR21 Abst#0076 @RheumNow https://t.co/oIvbak4lV4

Retrospective study of FAERS database: 186 irAE w/rheum manifestation 👉4.7% of all AEs 👉Arthritis, myositis, Sjogren, sarcoidosis were frequent 👉myositis assc w/ durvalumab, avelumab, atezolimumab and cemiplimab #ACR21 Abstr#0438 #Plenary @rheumnow https://t.co/t8UQWQicFc https://t.co/FGo6WCDQTp

• Rheumatological Immune-Related Adverse Events of Immune Checkpoint Inhibitors B…

@BethIWallace et al. on fibromyalgianess and GC in #rheumatoidarthritis pts. Accdg to their study, pts w/⬆ levels of fibromyalgianess at BL had higher odds of GC persistence on ffup. Something to consider when evaluating need for GC adjustment. @RheumNow #ACR21 abs0120 https://t.co/MTWEXGHJ2n

Retrospective study of cancer pts Rx w/ ICI and autoimmune Ab (ANA, RF, CCP, SSA/SSB, ANCA) 👉152 pts 👉59% had irAE 👉preICI Ab+⬆️odds of irAE (OR 17.5 95% CI 1.76-174, p=0.015) 👉strong assc b/t +RF and +CCP for ICD-arthritis #ACR21 Abst#0440 @Rheumnow https://t.co/kUv5ddSAnY

• Association Between Rheumatic Autoantibody Positivity and Immune-related Advers…