Filgo reduces PsA markers OP0224. ? Unique to filgo, a JAK1 effect , class effect or part of any effective PsA Rx or some of the above? @eular_org @RheumNow @CRASCRRheum @earlyarthritis #EULAR2020 https://t.co/2O5wsLPNl2

• https://twitter.com/DrPetryna/status/1269006416569827331

I've heard people say FDG uptake on PET/CT in PMR/GCA is just a correlate of systemic inflamm. Look at the uptake intensity (SUVmax) vs inflamm markers in n=65 PET/CT in GCA. There's no pattern whatsoever. Not just an expensive ESR! @FreemanHospital SAT0272 #EULAR2020 @RheumNow https://t.co/D4xAZC7KmO

In this unprecedented time, I must thank #EULAR2020 and @RheumNow for keeping all of us focused on the future. It’s inspiring and I needed the reminder! @KDAO2011 @CCalabreseDO @drdavidliew @DrPetryna @philipcrobinson @LCalabreseDO @RonanTKavanagh

To truly address adherence, you need to understand what is impairing it, and tailor an approach to overcome those barriers. Great to see this articulated in EULAR recommendations re: non-adherence - a big factor in our therapeutic outcomes! EULAR projects #EULAR2020 @RheumNow https://t.co/0pazcDFTuV

Is there subclinical GCA in PMR pts? 50 consecutive PMR pts had vascular USS. 27/50 had GCA vascular uptake, of which 10 had no GCA symptoms at all. Is PMR sometimes just the tip of the GCA iceberg? Do the aSx USS+ pts get GCA Sx eventually? Bonn SAT0254 #EULAR2020 @RheumNow https://t.co/UmsixY29Qh

#EULAR2020 OP0019 DON'T STOP TNFi in RA remission per ARCTIC-REWIND trial: RCT X 1 year n=99 multicenter gov't funded- DAS28 remission X1 year, dz X10 yrs, 2/3 pts (RF+/CCP+), no doppler signal. Results: 63% flared who had TNFi w/drawn vs. 5% when TNFi continued @RheumNow https://t.co/SsR1vUGbOe

Analysis of the UK THIN database shows that delays in receiving followup Denosumab injx results in higher fracture risk (vertebral & Maj OP Fx). 6144 infusions in 2594 pts, shows risk if delay is >16wks (long delay), but not if 4-16wks #EULAR20 SAT0453 https://t.co/DkJK3dHeRN https://t.co/r7ckpSF6PA

• https://bit.ly/2z6UhnA

H2H UPA vs ABA RCT; UPA is clinically superior to ABA in DAS-CRP remission, ACR50, ACR70 at wk 12/24 (NOT diff in Pain, FACIT, Boolean remission); But UPA has more serious AE (vs ABA) - esp hepatic, OI, SIE, SAE, CPK (but not zoster VTE) #EULAR20 SAT0151 https://t.co/K96lybdg7L https://t.co/vQM2MSCNzD

• https://bit.ly/3eXAaYu

Dr Mariette summarizes the evidence for using cytokine-targeted therapies in #COVIDー19 Several studies with favorable results with #Tocilizumab and #Anakinra, however, almost all with methodological limitations (e.g., historical groups) #EULAR2020 #EULAR20 #EULAR2020goesvirtual https://t.co/cMUKoeGfK9

VTE elevated risk is assoc up to 1 yr after high disease activity in RA 1% over 1 yr of active RA will get VTE OP0034 Data from Swedish popn study implications irrespective for which Rx pt gets? @eular_org @RheumNow @CRASCRRheum @earlyarthritis #EULAR20 #eular2020 https://t.co/A7mWoYZI9S

VTE are LESS in RA using TNFi vs csDMARDs and other bDMARDs from German large RABBIT registry. No JAKi in this analysis. HOT TOPIC. Also may be true for Crohns @eular_org #EULAR2020goesvirtual #eular20 @RheumNow @CRASCRRheum opening plenary https://t.co/RQVbY4ztGt

RA pts are at risk of pneumonia, & inflamed lung mucosa can produce RF/CCP. Are these linked via subclinical lung injury? Seropos RA pts @BrighamWomens have double the pneumonia risk post-adjustment. We're still learning more about RF... @jeffsparks OP0111 #EULAR2020 @RheumNow https://t.co/C3CYpXABGc

GCA and cancer: it's been hard to tease apart, lots of cofounders. We've needed large cohorts with comparators & detail. Large Israeli database says there are links (EMR/claims/prescribing combined, n = 4.4m w validated incident GCA set). If so, why? OP0143 #EULAR2020 @RheumNow https://t.co/kSPGnxNjah

AAV/PAN and cancer: risk from meds has always been the question. Interesting therefore that GPA/MPA pts accumulated incident cancer risk over time, whereas other AAV/PAN pts had risk early after dx... Jo Tieu 🇦🇺@earlyARA @helenkeen73 @CatherineL_Hill OP0145 #EULAR2020 @RheumNow https://t.co/8ywycZuMHV

Tenosynovitis is underrated in RA. A nice reminder from an Argentinian group, who USS scanned 90 RA pts in clinical remission >3m and followed them for 12m. Subclinical synovitis did not predict flares, but subclinical tenosynovitis did (adj OR 9.8) THU0119 #EULAR2020 @RheumNow https://t.co/kcle8qyQbI