Poor prognostic factors for MDA-5 ILD: - Ferritin > 1000 ng/mL prior Rx - GCO or consolidations in all lung fields - Worsening of lung consolidations during Rx #ACR19 @RheumNow

Myositis -- Ask for muscle biopsy when: - high clinical suspicion w/ negative myositis specific antibodies - high clinical suspicion of inherited muscle disease - isolated elevated CPK - recalcitrant to treatment - atypical presentation #ACR19 @RheumNow

Sjogrens RCT of Tocilizumab showed no benefit. Wonder re outcomes and pt selection. Maybe pick early pts with high inflammatory markers or other organ involvement #ACR @RheumNow #Sjogrens abstr1904

Tofacitinib works in Polyarticular JIA. Maybe new hope for kids with JIA and benefits of oral medication #ACR #ACR19 #JIA @RheumNow L23.

Myositis-specific autoantibodies (MSA): an important tool to support the diagnosis of myositis #ACR19 @RheumNow https://t.co/vgW2wxkemr

Certrolizumab pegol decreases uveitis in open label study of SpA with past uveitis and HLAB27 group enriched for recurrence. Pre and post Rx rates of uveitis were compared. 80% reduction of uveitis but uncontrolled and unblinded. #ACR #ACR19 @RheumNow

1/3 of pts using apremilast with PsA/SpA from Corrona data base are using it in combination with bDMARDs. Not sure how they get reimbursement #ACR #ACR19 #psoriaticarthritis @RheumNow abstract 1481

2020 Gout Clinical Practice Guideline ❕Regardless of disease activity, conditionally recommend - limit alcohol intake - limit purine intake - limit high-fructose corn syrup - if overweight/obese, recommend weight loss - against adding vitamin C supplementation #ACR19 @RheumNow

@RheumNow 2020 Gout Clinical Practice Guideline ‼️ For allopurinol and febuxostat, strongly recommend starting at low dose with subsequent dose titration to target over starting at higher dose ( ≤ 100 mg/d for allopurinol, ≤ 40 mg/d for febuxostat) #ACR19 @RheumNow

Gout guidelines make total clinical sense. Congrats ACR and Goit me@bers for a monumental job #ACR @RheumNow https://t.co/A0iwU0WPlZ

• Gout Study Group on Twitter: "2020 DRAFT ACR #gout Clinical Guidelines str…

All the NEW Clinical Practice Guidelines for GOUT! 1. Allopurinol is 1st line 2. Start ULT during flare! 3. No tx for asymptomatic hyperuricemia Seems pretty reasonable - surprised no rec for MTX w/pegloticase #ACR19 @RheumNow Thank you to @philipcrobinson for posting slides! https://t.co/riwHGYNZ8T

2020 Gout Clinical Practice Guideline 42 recommendations (16 strong) - 27 ULT management (13 strong) - 5 Gout Flares (3 strong) - 5 Lifestyle recommendations - 4 Management of other medications - 1 Asymptomatic Hyperuricemia #ACR19 @RheumNow

Pericarditis is an inflammatory condition that causes chest pain, pericardial friction rub, pericardial effusion. #ACR19 @RheumNow

MAXIMISE results in axial manifestations of PsA. SEC met primary phase 3b ASAS 20 endpoint after inadequate NSAID response. https://t.co/e1j03KOo1K #ACR19 @RheumNow abs#2880 https://t.co/UtSDJGAW2G

• Secukinumab Improves Axial Manifestations in Patients with Psoriatic Arthritis …

The draft 2020 ACR #gout guidelines were presented at the last slot of the meeting. Big changes for ULT initiation #ACR19 @RheumNow [Slides attached] https://t.co/bHBzQ3xwX8

• https://static.coreapps.net/tristar-acr19/handouts/b5918279-09dc-4a7f-b2c9-059c…