Basic truths of irAEs: Symptoms do not equal irAEs, in diarrhoea/colitis as in arthralgias/arthritis. Substantial proportion excluded on investigation Local site Rx where possible: because they often work, and systemic steroids still can’t be exonerated #ACR19 @RheumNow https://t.co/TJHQkKcvX8

Normal inflamm markers in PMR: 14% (62/454) of the Nijmegen PMR cohort fell in this group, and they had similar rates of follow-up, steroid dependence, even similar rates of GCA (albeit low). A subgroup of PMR we need to understand better! Diane Marsman #ACR19 ABST0759 @RheumNow https://t.co/XS2bPrWKUf

One of the hardest things about PMR is getting a reliable diagnosis - no biomarker and no histopath. Imaging has potential, and my colleague @drceowen has made a simple algorithm for reliable/replicable PET/CT dx 👍 @DrCMcMaster @jlyleung @Austin_Health #ACR19 ABST0755 @RheumNow https://t.co/JGswa6Wjju

The C-AxSpand study, Certolizumab-treated nr-axSpA pts with shorter symptom duration (< 5 vs ≥ 5 years) showed greater improvements across signs and symptoms of disease and in quality of life. Kay J et al #ACR19 @RheumNow

REDO trial: ultra low dose Rituximab for RA 500mg x 1 or 200mg x 1 compared against 1000mg 6mo non-inferiority Could not formally show this but for many, ultra-low doses appeared effective Should lead to longer term & tapering studies #ACR19 @rheumnow Abst0931

A Phase 2b study demonstrated the sustained efficacy of bimekizumab in pts with active AS to Week 48. Bimekizumab was generally well tolerated and no new or unexpected safety findings were identified #ACR19 @RheumNow

You can treat all of the Hep C all of the time - but you won’t get rid of related cryoglobulinaemic vasculitis >10% of the time. SVR with DAA in HCV does not equal vasculitis cured! (PS you can even get it de novo after SVR) n=1019 Egypt, France, Italy #ACR19 ABST0948 @RheumNow https://t.co/Lp3ZVMwTgj

Here is result to save you looking it up in this highly refractory group #ACR19 @rheumnow Abst0930 https://t.co/gYv7CZcMvL https://t.co/ToIavKEn4z

• Dr Irwin Lim on Twitter: &quot;Wireless vagus nerve stimulation for 14 RA pts &…

Abstr# L14: data shows that in PsA you’re able to withdrawal MTX from the combo of tofacitinib+MTX without any loss of efficacy. Great news, because pts really like to minimize their meds when possible. #ACR19 @rheumnow https://t.co/3cDoTc1gWB

@RheumNow #ACR2019 ABS899 Tart cherry concentrate had NO effect on serum urate, urine urate excretion or the frequency of gout flares over 28-day study period (p=0.76). However, those receiving allopurinol had significantly greater increases in urinary anthocyanins (p< 001) https://t.co/JJm9RCILoH

The amazing @GrantSchulert helps us begin to understand sJIA-associated lung disease #ACR19 @rheumnow #Abstr #ACRBest https://t.co/NGnjEYDBnL

How would vagus nerve stimulation help Rheumatoid Arthritis?? #ACR19 @rheumnow Abst0930 https://t.co/NupaKJkXCL

The C-VIEW open-label study found a significant reduction in the AAU flare rate in axSpA pts with a history of recurrent AAU during the first 48 wks of Certolizumab. Pts also experienced significant improvement in axSpA disease activity #ACR19 @RheumNow

@RheumNow #ACR19 ABS377 Stanford Univ retrosp stdy of pts w/ cardiac sarcoidosis supports use of TNFi in pts who failed cDMARs. Pts were able to reduce steroids dose w/no decline in LVEF in pts with preexisting CHF. larger, prospect studies needed