D White WIRheum
8 years ago
B cell immunology
New therapies directed at B cells
Overlap with therapies for myeloma
How to target long-lived (CD20 neg) plasma cells?
Session: ACR immunology update
Roundup - Cush, Kavanaugh
#ACR18 @RheumNow
D White WIRheum
8 years ago
Session on draft ACR reproductive health guidelines
Three manuscripts in preparation
This effort is a response to a tremendous need for info and guidance
Estimated half of pregnancies are unplanned, so ask patients often
Roundup - Cush, Kavanaugh
#ACR18 @RheumNow
D White WIRheum
8 years ago
MTB screening in patients on TNFi
When to re-screen?
Neg to pos conversion discovered in a small number of cases
Often in patients with risk factors
Cush: Annual testing “makes no sense at all"
Abs 1234, Rochester NY
Roundup - Cush, Kavanaugh
#ACR18 @RheumNow
D White WIRheum
8 years ago
DIP involvement in RA
12k patients in Japanese registry
2% incidence, 2-3 joints in each pt with involvement
associated with higher disease activity
Abs 221
Roundup - Cush, Kavanaugh
#ACR18 @RheumNow
D White WIRheum
8 years ago
Biosimilars in Sweden
Rx patterns (originator vs biosimilar) follow prices - back and forth
Abs 1175
Roundup - Cush, Kavanaugh
#ACR18 @RheumNow
D White WIRheum
8 years ago
Gout
Remains under-treated
Higher success when pharmacists and RNs manage ULT
Abs 2220, 1247, 1272
Roundup - Cush, Kavanaugh
#ACR18 @RheumNow
D White WIRheum
8 years ago
Enthesitis, in particular supraspinatus tendinopathy
IL-17A as a target of therapy
Abs 404
Roundup - Cush, Kavanaugh
#ACR18 @RheumNow
D White WIRheum
8 years ago
MTX helpful for granulomatous mastitis
Can be recurrent; sometimes seen by rheums
Rule out cancer, infection
Abs 2264
Roundup - Cush, Kavanaugh
#ACR18 @RheumNow
D White WIRheum
8 years ago
Chronic back pain in patients with a FHx of ank spond
More psoriasis and heel pain
Undiagnosed SpA?
Abs 637
Roundup - Cush, Kavanaugh
#ACR18 @RheumNow
D White WIRheum
8 years ago
High- vs standard-dose influenza vaccination in pts on DMARDs and biologics
High-dose quadrivalent version more effective (seroconversion) except in rituximab population
Abs 837
Roundup - Cush, Kavanaugh
#ACR18 @RheumNow
D White WIRheum
8 years ago
MTX vs etanercept vs combo in PsA
ACR20 at 24 wks: 50%, 60%, 65%
Contrast TEMPO study in RA where combo therapy was better than monotherapy
Also: MTX monotherapy effective
Abs L11
Roundup - Cush, Kavanaugh
#ACR18 @RheumNow
D White WIRheum
8 years ago
Plasma exchange in AAV (GPA or MPA) with severe disease
PLEx did not reduce ESRD or death
Reduced-dose glucocorticoids did not increase risk of death or ESRD (but did have fewer infections)
Abs 2788
Roundup - Cush, Kavanaugh
#ACR18 @RheumNow
ǝlʇʇıɥʍ ɯɐs samwhittle
8 years ago
Top Influencers of #ACR18 👉 @RheumNow @CreakyJoints @ACRheum @ArthritisFdn @psufka @DrJuanOvalles https://t.co/9ouTIWOqac via @symplur
The ACR/ARHP 2018 national meeting in Chicago presented us with opportunities to learn more about inflammatory myositis. A particularly interesting lecture was HOT topics in myositis. There were a few abstracts on MDA-5 related disease and a few on new or repurposed medications for dermatomyositis which will be covered here.
Nicole Bitencourt NicoleBitencou5
8 years ago
Dr. Berent Prakken reviews. IL18 may be a diagnostic biomarker for MAS in systemic JIA (compared to familial or primary HLH)
#pedsinreview #ACR18 @rheumnow
