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Idiopathic Interstitial Pneumonia with Autoimmune Features - or IPAF - describes patients with interstitial pneumonia with autoimmune features, but they don’t meet a diagnosis of a CTD.
PPP syndrome = a rare triad

πŸ‘‰ Pancreatitis + Polyarthritis + Panniculitis

πŸ”¬ Pathogenesis: circulating pancreatic

ILLIASUL IBAD IlliasulK

10 months 1 week ago
PPP syndrome = a rare triad πŸ‘‰ Pancreatitis + Polyarthritis + Panniculitis πŸ”¬ Pathogenesis: circulating pancreatic enzymes (esp. trypsin) β†’ fat necrosis in subcutis & bone marrow. πŸ“Œ Clue: painful nodules + arthritis, often with minimal abdominal symptoms. #Rheumatology https://t.co/3qniCmahgl
Inception SLE study of 674 pts (without LN), mean age 34 yrs - 154 (23%) developed new proteinuria (LN) after median of

Dr. John Cush RheumNow

10 months 1 week ago
Inception SLE study of 674 pts (without LN), mean age 34 yrs - 154 (23%) developed new proteinuria (LN) after median of 3.6 yr. Cumulative antimalarial exposure did NOT lower risk of LN (HR 0.98; 0.94-1.02); same for those w/ serologically active SLE (HR 0.97) https://t.co/8OU3yJAvhN
A French early rheumatoid arthritis (RA) study has shown that polypharmacy (PP) was associated with significant lower treatment responses and more serious adverse events (SAEs). 
OL study of 60 pts w/ new idiopathic retroperitoneal fibrosis (GFR >30) Rx w/ low dose MTX+pred VS Pred only. @ 9 mo

Dr. John Cush RheumNow

10 months 1 week ago
OL study of 60 pts w/ new idiopathic retroperitoneal fibrosis (GFR >30) Rx w/ low dose MTX+pred VS Pred only. @ 9 mos remission: 90% MTX+Pred vs 81% Pred (noninferior). Time-to-remission, RPF thickness & relapses were same; but pred use was lower w/ MTX+pred (p < 0.001) https://t.co/13cjnl4Ke4
Turkish study of 799 psoriasis pts - 30% had concurrent onset PsO & PsA & in 70% there was a long transition tim

Dr. John Cush RheumNow

10 months 1 week ago
Turkish study of 799 psoriasis pts - 30% had concurrent onset PsO & PsA & in 70% there was a long transition time (~13 yrs) from PsO-to-PsA. Factors assoc w/ prolonged interval included Depression, fatigue, scalp PsO(OR 7), nail PsO (3.2), +Fhx & enthesitis ever (OR 2) https://t.co/wqtSbeQ2vz
Canakinumab in VEXAS - 47 males Rx w/ anakinra (44), canakinumab (9), or both(6). Response @1 mos: ANAK 34% vs CANK 100%

Dr. John Cush RheumNow

10 months 1 week ago
Canakinumab in VEXAS - 47 males Rx w/ anakinra (44), canakinumab (9), or both(6). Response @1 mos: ANAK 34% vs CANK 100%; 22% vs 78% @ 3 mos. Drug survival was 54 mos CANK 300/m; 7 mo CANK 150/m; 1 mo ANAK. More ISR (47% v 0) & infx w/ ANAK https://t.co/Y3iSfajTal https://t.co/qTNamGDwVI
Prospective French study of 101 RA-ILD (mean 66yrs) assessed for shorter WBC telomere length (LTL); short LTL seen in 43

Dr. John Cush RheumNow

10 months 1 week ago
Prospective French study of 101 RA-ILD (mean 66yrs) assessed for shorter WBC telomere length (LTL); short LTL seen in 43% & assoc w/ lower FVC (82% vs 93%pred) & TLCO (49% vs 63%) & greater FVC/DLCO decline & lung progression after 12 mos (47% vs 22%; p<0.001) https://t.co/ObVeon0riy
Monthly survey - 351 ArthritisPower #RA Registry pts reported 523 nonserious infxns (31% ; most URI), few resulted in

Dr. John Cush RheumNow

10 months 1 week ago
Monthly survey - 351 ArthritisPower #RA Registry pts reported 523 nonserious infxns (31% ; most URI), few resulted in ED or hospitalization. But NSIA led to missed work (37%) or RA Rx interruptions (26%) and more fatigue. NSIE may contribute to more disease flares https://t.co/Al5B5oxvFg
Scientists have discovered that rheumatoid arthritis (RA) doesn’t start when the pain begins. It silently starts years earlier.The new research reveals that people at risk for RA experience dramatic immune system changes long before they feel symptoms.  β€―
DERM on RheumNow Podcast (September 2025)

Content curated for dermatologists and skin deep HCPs – on Psoriasis, CLE,

Dr. John Cush RheumNow

10 months 1 week ago
DERM on RheumNow Podcast (September 2025) Content curated for dermatologists and skin deep HCPs – on Psoriasis, CLE, vasculitis, HS and dermatology drugs use, efficacy and side effects and more. https://t.co/zZpheX1epS https://t.co/uOd9Gy0V2E
QD Clinic: Stick or twist (when not to change treatment

Dr. Richard Conway, Dublin, discusses a case about when not to

Dr. John Cush RheumNow

10 months 1 week ago
QD Clinic: Stick or twist (when not to change treatment Dr. Richard Conway, Dublin, discusses a case about when not to change treatment, as part of RheumNow's Rheum to Breathe: ILD campaign, presented throughout the month of September 2025. https://t.co/kUopZ1bpVi https://t.co/mt0tKcQzKQ
Rheum to Breathe Journal Club
Assessing ILD in Rheumatology

Janet Pope, MD, shares practical insights on how rheumatologists should assess ILD in the

Dr. John Cush RheumNow

10 months 1 week ago
Assessing ILD in Rheumatology Janet Pope, MD, shares practical insights on how rheumatologists should assess ILD in their patients. Sponsored By: Boehringer Ingelheim https://t.co/Mxg9P50m7C #ILD #Rheumatology https://t.co/aAuxbJBxBn
Scleroderma-associated Interstitial Lung Disease

Since the first placebo-controlled randomized trial published nearly

Dr. John Cush RheumNow

10 months 1 week ago
Scleroderma-associated Interstitial Lung Disease Since the first placebo-controlled randomized trial published nearly 20 years ago for the treatment of patients with SSc-ILD, evaluating cyclophosphamide vs. placebo, there have been several other randomized studies to guide the https://t.co/Dh7XpP6qhF
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