Can tissue give us an underlying diagnosis in aortitis? Dr. Kermani breaks down the autoimmune differential based on histopathology @RheumNow #ACR25 https://t.co/twcH021dxS

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Abstract 0842 💡 Urinary biomarkers as the next frontier for monitoring lupus nephritis activity 🔹 Proteinuria didn’t track w/ histologic activity 🔹 IL-16 & sCD163 correlated at baseline only 🔹 Urinary Tenascin C & BAFF correlated w/ activity at 1 yr @RheumNow #ACR25

2 year extension data from SELECT-GCA: Patients in remission who remained on upadacitinib 15mg daily after 1 year had 90% reduced risk of flare compared to those who switched to placebo Higher rates zoster, CK elevation in UPA group #ACR25 @RheumNow #ACRBest https://t.co/jf8Dh2wCBj

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The differential diagnosis for CNS vasculitis is BROAD. Keep in mind it’s mimics @RheumNow #ACR2025 https://t.co/ASWr6zm5eQ

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Social media based outreach to pts for research Out of 617,207 users engaged, 6 filled the contact form Based on this social media (knowing also promotion costs) might not be the best strategy to recruit for clinical trials @RheumNow #ACR25 https://t.co/qCH9WXyTD7

• https://twitter.com/drdavidliew/status/1982541142316253359

💊 SGLT2i vs GLP-1 in Lupus Nephritis TriNetX evaluating the impact of GLP-1 agonists vs SGLT-2 inhibitors on outcomes of lupus nephritis 📊 GLP-1 use linked to better renal & CV outcomes in LN including: ⬇️ CKD progression ⬇️ Mortality ⬇️ Acute MI @RheumNow #ACR25 https://t.co/v4LgKFDt68

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Could a sputum test predict risk for RA conversion in at-risk patients? 98 at risk pts, Converters had higher -BL sputum CCP levels -BL Sputum nucleosome and cit-nucleosome levels !although not asso after adjusting for sputum anti-CCP-IgA level In converters, correlation of https://t.co/bqmQqS1Jz5

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Where do patients find informations about their RMD? Study of 705pts -80% search engines via smartphone 80.3% Different pattern within 2 yrs of diagnosis vs. later stage: -more frequent 19% vs 8% Most users find online content -understandable 80% -apply it in daily life 68% https://t.co/9IMvpt2ffr

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More biomarkers predictive of conversion to clinical RA in at-risk pts Serum PAD4 & PAD 4 levels measured in CCP+ at-risk individuals -PAD4 (not PAD2) increased in RA Converters vs. non converters and HC -PAD4 levels Pre-RA = RA Within high CCP+ at risk individuals, higher https://t.co/LU5zUzui1G

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Trying to reach RA, PsA patients on social media, to participate in studies? Simple, informational messages work for recruitment Message framing affects engagement but not recruitment The more we understand, the better we can reach the right people #ACR25 ABST0187 @RheumNow https://t.co/JoAthXhXvi

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A simple flow cytometry analysis of peripheral blood monocytes to predicts progression to clinical RA or PsA in at-risk patients? Too good to be true! 284 RA 56 PsA 57 HC -HLA-DR higher in PsA -CD11c lower in RA But no clear difference between Converters and non Converters https://t.co/f3Sett4eXd

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Rheumatologists love AI scribes in clinic. The way we interact is potentially well suited, and accuracy and synthesis quality is bound to improve. Is it inevitable that it will universally be standard practice for us soon? UCSF clinics #ACR25 @JYazdanyMD ABST0189 @RheumNow https://t.co/kOzfpLlvgD

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CMV is a worry with high-dose steroids, especially in certain settings. The risk is far from universal, though: in this Korean cohort treated with high dose pred, almost no-one without risk factors got it. Meds are rarely the only infection risk factor #ACR25 ABST203 @RheumNow https://t.co/zLYhLVKgYL

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