Different B cells depletion strategies in SARDs highlighted by Georg Schett From low and short lived depletion achieved w/ drugs to sustained deep tissular depletion with CAR T cells leading to potential immune reset @RheumNow #APLAR25 https://t.co/t35lrzEomF

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Juvenile Lupus: some new mechanistic data Circulating Treg population are expanded in SLE and in particular in Lupus Nephritis compared to HC Naive Treg display specific molecular features in particular over expression of FCRL3 and TLR5 showing new pathways to explore in https://t.co/RuMtWRkpYB

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PAH, when associated with ILD in CTD, worsens prognosis, and poses challenges for treatment Summary of when PAH should be assessed in patients with ILD and when to perform a right heart catheterization by Prof Kuwana @RheumNow #APLAR25 https://t.co/g4x4ENzc9k

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Dr. Alberta Hoi graphically presents the difference bet acute confusional states & chronic cognitive changes in #lupus patients presenting with NP symptoms. NPSLE continues to pose a diagnostic challenge bec pts may present with more than one syndrome complex @RheumNow #APLAR25 https://t.co/4nYTo1fzVz

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How to treat CTD ILD? A comparative slide summarizing ACR/BSR and EULAR treatment guidelines Emphasis on combination of Immunosuppressant and Antifibrotics @RheumNow #APLAR25 https://t.co/gLSht6QKh5

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“Listen to the patient, he is telling you the diagnosis”. – Sir William Osler

A framework for treatment stratified approach in CTD-ILD, by Dr Low Hsiu Ling Based on -ILD extent -Risk of progression -Biology: fibrosis/inflammation -Safety -Other manifestations @RheumNow #APLAR25 https://t.co/ma5KugzBHy

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‼️More reasons why we should avoid steroids in #lupus patients @RheumNow #APLAR25 https://t.co/a5IeutJ5mi

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Why shall we screen all patients with SSc for ILD? Focusing screening strategy on patients « at risk » misses 25% of patients with ILD ILD being the main cause of mortality in SSc @RheumNow #APLAR25 https://t.co/djzCTdZoVb

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The overall prevalence of #osteoporosis in SLE is ~33-40% and is due to several factors with GC therapy being one of them. Monitor DXA every 6-12 months (vs. 2 yrs for standard OP) ☝️Screen for GIOP ☝️Treat accordingly - once on GCs & esp w/long-term use @RheumNow #APLAR25 https://t.co/E9FJDHrBUo

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Paradigm shift in CTD PAH -Early triple therapy in patients with intermediate and high risk -Sotatercept, a blocker of activin-Smad2/3 signaling have increased survival importantly Data presented by Dr Khanna @RheumNow #APLAR25 https://t.co/Z4yA6DwtOb

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An important message from Prof. @XBaraliakos on D2M-axSpA: Re-evaluate your diagnosis & check for comorbids before labelling pts as tx-refractory or difficult-to-manage. consider other causes: FM, other causes of pain @RheumNow #APLAR25 @rheumarhyme @marklagacmd https://t.co/Lo0yShOK0P

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Drivers of costs associated with economic costs of RMDs in Asia Pacific -Traditional medicine -Loss of income much higher if worker as opposed to unpaid household labor so high impact of gender roles -Impact of out of pocket health payments due to « catastrophic spendings » in https://t.co/sptwGE7J2V

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Prof. Aletaha shares their AutoPiX project - using AI to develop quantitative biomarkers. Something to look forward to since imaging remains an important diagnostic tool in #rheumatology @RheumNow #APLAR25 @rheumarhyme https://t.co/WExT9amazz

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Update on Rheumatology workforce shortage in Asia-Pacific Date presented by Dr Ahmad Number of Rheumatologists per 100000 inhabitants across @APLAR_org countries -3 in Japan -1.3 in Australia, Hong Kong, Singapore -0.03 in Pakistan As a result: delayed diagnosis for patients! https://t.co/Hycqtp8BtY

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