Biologics in Pregnancy Patients With Autoimmune Disease A large cohort, claims data study shows that among pregnant women receiving biologic therapies for autoimmune conditions, 72% continued their biologics pregnancy, more so among inflammatory bowel disease (IBD) patients https://t.co/CH60gShlH0

Lupus Clinical Slides: Set 1 https://t.co/zFQqHfl8Ch https://t.co/kvVNAS17ec

• Lupus Clinical Slides: Set 1 | RheumNow

SLE, Antiphospholipid Antibodies, and the Placenta It is well established that women with SLE are at increased risk for adverse pregnancy outcomes, including preeclampsia, preterm birth, and pregnancy loss. However, the pathophysiologic mechanisms driving these complications https://t.co/z0BOT3xsuQ

Why DORIS or LLDAS #remission 🤔 ⬇️mortality ⬇️damage ⬆️QoL Dr Nikpour at On Rheum Assoc Shows Remission > LLDAS no pred ✅ best @RheumNow https://t.co/tFcPrkd5Vd

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• https://x.com/Janetbirdope/status/1926255397511282889/photo/1

🍋 or ‘Lyme’ - is it Lyme disease? Dr Elizabeth Stringer discusses Eastern Canada 🇨🇦 Epidemic of #Lyme #arthritis Which mimics #pauciarticular #JIA When it is #chronic Work up of all oligoarthritis in endemic areas in kids Includes Validated Lyme test @ORAexec #ORA25 https://t.co/WxU1vaOa7z

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Does ADDING an #immunesuppressive To #belimumab in #SLE give more benefit? ❎ NO #RWE from Spain suggests no added improvement adding IS to Belimumab Should you switch Rx then? 🤷‍♀️ @RheumNow #LUPUS2025 poster110 #ClinicalPearl https://t.co/C3ydArMx7x

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Treat to target 🎯 #SLE #recommendations Considerations are nuanced and Impt Lowest clinical disease activity is goal Try for remission 🎯 Get patients off #glucocorticoids If not ⬇️low dose #prednisone @RheumNow #LUPUS2025 https://t.co/HlBeh2FLxP

• https://x.com/Janetbirdope/status/1926272862970613779/photo/1
• https://x.com/Janetbirdope/status/1926272862970613779/photo/1

Lupus QD Clinic - Rhupus dsDNA+ SLE Plus CCP+ RA = Rhupus https://t.co/lyV7fgd1vp https://t.co/Ptw0dmyqCj

• Lupus QD Clinic - Rhupus | RheumNow

Lupus in an empty house The full house immunofluorescence pattern is the classic histopathologic finding of lupus and lupus nephritis. Glomerular deposits staining for IgG, IgA, IgM, C3 and C1q can help confirm a suspected diagnosis of systemic lupus erythematosus (SLE). This https://t.co/Zcywc5r9q9

Lupus Unlocked: Pregnancy & SLE 📅 May 27, 2025 6:00 PM CT | 7:00 PM ET | 4PM PT Join us for our final Lupus Unlocked webinar this month on pregnancy and SLE. In this webinar, panelists will discuss issues such as congenital heart block, lupus nephritis treatment, teratogenic https://t.co/gouTN7uzCo

Unmet needs in #lupus are many 👇 Timely #diagnosis Morbidity - CV, metabolic, OP, mental health Premature mortality - CAD, active #SLE, infection Issues w pregnancy #steroid side effects ⬇️QoL With partnerships we can ✅ Pts HCPs researchers Pharma Gov’t #LUPUS2025 @RheumNow https://t.co/9T9rIrM1hV

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IL2 low dose in #SLE seems to + alter immune regulation Multiple targets to explore in #lupus Unravelling pathophysiology in SLE CD40L TLR7,8 #rapamycin type drugs CAR-T w novel CARS Etc #LUPUS2025 @RheumNow https://t.co/jeycgg4ZhT

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>200 genes 🧬 implicated in #SLE Complex indeed! And ▶️ 7 clusters of signalling pathways So we have to have many Rx options Ab patterns vary LN flares can have v diff pathways between Pts #LUPUS2025 @RheumNow Unravelling #LUPUS2026 https://t.co/LEKN363194

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We are not (yet) in #SLE Getting 👇 Correct drug In right pt At right time At correct individual dose Even more problematic is in a renal bx - 2 glomeruli beside each other have v different cytokine expressions Unravelling #LUPUS2025 @RheumNow https://t.co/yGBvhFkPKY

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• https://x.com/Janetbirdope/status/1925963041717264457/photo/1

Here’s who flares in #SLE least to most Persistently neg antiDNA Persistently + antiDNA conversion of neg to + antiDNA So are we over ordering antibodies in 1st 2 groups 🤷‍♀️ Unravelling #LUPUS2025 @RheumNow https://t.co/1Feau7f199

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