RheumNow’s expanded coverage of the #ACR24 Annual meeting is sponsored in part by Novartis. All content is chosen by RheumNow & its faculty

In order to have a #DMOAD in knee #osteoarthritis ➡️ early detection may be v important Study of early pt Symptoms was done 2/3 had pain 1/2 #joint Swelling Need biomarkers & sensitive imaging in early #OA as symptoms are NOT uniform #ACR24 @RheumNow @ACRheum abst2111 https://t.co/K94m9rOjtP

• https://x.com/Janetbirdope/status/1858707170688159882/photo/1

Pts w #osteoarthritis and T2 DM 👇 Who Have ⬆️pain Have worse control of #diabetes Even after adjusting for #BMI Chicken or egg - which comes 1st 🤷‍♀️ #ACR24 @RheumNow @ACRheum Abst#2110 https://t.co/eN2xAw0EMG

• https://x.com/Janetbirdope/status/1858708597636513900/photo/1

Does #hand #osteoarthritis Benefit from #traction #splinting? Nope 👎 Small 2 site #RCT - not helpful I may Recommend #splinting - sometimes pts get Pain relief - in my opinion but this one didn’t help #ACR24 @RheumNow @ACRheum Abst#2108 https://t.co/K0Ud7uCb1P

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How long is a long acting #intra-articular #steroid #injection in #knee #osteoarthritis? #IA steroids can be q3monthly #RCT of IA #fluticasone #propionate Was superior to #placebo Seemed to last approx 24 weeks ➡️ sub analysis in moderate pain, BMI<30 #ACR24 @RheumNow #2106 https://t.co/QBFCqXd1Q8

• https://x.com/Janetbirdope/status/1858722471156851072/photo/1

#Scleroderma #molecular #signatures in #skin predict long term outcomes 👇worst with inflammatory signature This may have clinical and trial applicability Nice work! Abst0711 #ACR24 @RheumNow @ACRheum https://t.co/3CFxu6bACu

• https://x.com/Janetbirdope/status/1858726160173052014/photo/1

#PAH in #SSc still has a poor #prognosis 👎 Esp #ILD with PAH - a double whammy But also group 1 PAH And Some are unclassifiable ▶️also bad px Need Earlier detection More interventions ?prevention Abst#0678 #ACR24 @RheumNow @ACRheum @sclerodermaUM https://t.co/AEQsTC1pzQ

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#Positive #RCT of #Nipocalimab a FcRn receptor inhibitor in #Sjogrens #Disease 👏Phase 2 +RCT ESSSDAI and ESPRI both improved 🤷‍♀️what it means to lower #antibodoes #Ro #La Excited for Phase 3 results #ACRBest #ACR24 @RheumNow @ACRheum abst#2527 https://t.co/NeeYT7VR16

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#MDA5 #dermatomyositis assoc #ILD May do better w #tofacitinib vs #CNI in 515 pts Too bad they didn’t do a pragmatic RCT as we do t know the reasons for prescribing each #Rx But impressive survival w #tofa #ACR24 @ACRheum @RheumNow abst1736 https://t.co/HLJknSYcNJ

• https://x.com/Janetbirdope/status/1858740087636312543/photo/1

Autoantibody tests are everywhere, but how do we make sense of them? With the proper algorithms, can we go beyond interpretation to predicting autoimmunity before it develops? Check out my article: Taking the AI out of AutoImmunity https://t.co/d3ZNYWQaaQ @RheumNow #ACR24

• Taking AI Out of AutoImmunity: Predicting disease before it develops | RheumNow

Risk stratification of GCA pts: who might lose vision? Cranial MRI with vessel wall enhancement used to calculate additive score... # of vessels affected Higher scores a/w ocular GCA > non-ocular GCA > no GCA and decreased w/ tx @RheumNow #ACRbest #ACR24 https://t.co/knDVrl84Qs

• https://x.com/Dr_Brian_MD/status/1858673873157328949/photo/1
• https://x.com/Dr_Brian_MD/status/1858673873157328949/photo/1

Conversation with @RheumKay on his #ACR24 biosimilar talk for @RheumNow https://t.co/LzAIGIG4wu https://t.co/CqSYLpJYAh

• What's The State of Biosimilars?
• https://twitter.com/ericdeinmd/status/1858547083017363622

@drceowen @TheLancetRheum @RheumNow Efficacy in newly diagnosed & established PMR is not necessarily interchangeable different treatment paradigm ?different immunologically Many other diseases have different Rx for induction vs maintenance, early dx vs established. Having said that: doesn't look great for MTX. https://t.co/89lByaYdYq

• https://x.com/drdavidliew/status/1858693549333901326/photo/1

Lot said about #ACR24 ABST1697: MTX in newly diagnosed PMR, neg RCT Many have said no hope for MTX in PMR now Agree doesn't bode well However, MTX may still have role in established PMR @drceowen & I have made that call a priori @TheLancetRheum https://t.co/ywCJc0zHzC @RheumNow https://t.co/JUXk2tDNyR

• Designing studies in newly diagnosed versus established polymyalgia rheumatica
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