❔Can rheum drugs have beneficial effects on cognition? 💊Possible benefits with MTX and TNFis but certainly an active area of research and more studies needed #ACR24 @RheumNow https://t.co/lCnIRLwNjK

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#ACR24 abst#0430 - Analyzed 61 SLE pregnancies - Higher early gestational Mean Arterial Pressure before 20 Weeks linked to increased preeclampsia risk - MAP trends at 8-10 and 17-19 weeks showed highest predictive accuracy for risk prediction @RheumNow https://t.co/37mg0WX43v

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Ab#474 #ACR24 Hsieh and @NamrataRheum Cancer Survival in RA Unable to do meta-analysis due to lack of data HR for lung cancer in RA 1.04 No clear evid of increased risk, but more data and studies needed Great research project by a high school student (!!) @RheumNow https://t.co/Sfrf2v2UO4

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Global meta-analysis of 61 studies shows TB Preventive treatment (TPT) - Reduces active TB risk in rheumatic disease patients by 29% (RR: 0.71, CI: 0.57–0.87) - Best outcomes in high TB-burden countries (RR: 0.51) and with isoniazid for >9 months (RR: 0.52). - Dual screening… https://t.co/4P1982ngvL

• https://x.com/i/web/status/1857846093033386184

Gender based response in Axial SpA. A hot topic at ACR @ACRheum @RheumNow @hac28 @SPARTAN_Updates https://t.co/zbnE6kjQhL

• https://twitter.com/adelacastro222/status/1857815900935635319

Ab#0458 #ACR24 10 year outcomes of 176 patients with seroneg RA 32 pts (18%) had change in dx - SpA (11), seropos RA (6), OA (5), crystal (3), CTD (3), Ifn-related/paraneopl/RS3PE, sarcoid (1) 40 (23%) had drug-free remission 30 (17%) started b/tsDMARD @RheumNow

FDA recently approved - fms-like tyrosine kinase 1 (s-Flt1) / placental growth factor (PlGF), for diagnosing preeclampsia. sFlt1:PlGF≤38 rules out preeclampsia in SLE sFlt1:PlGF>85 modestly predicts preeclampsia Proteinuria impacts prediction accuracy #ACR24 abst#0809 @RheumNow

Langford et al. Abatacept NOT effective in GPA in ABROGATE RCT. 65 patients. Relapse/worsening in 62% vs 68%. No difference in any secondary end-point. @RheumNow #ACR24 Abstr#0823 https://t.co/yRFZ2diJFF https://t.co/LgXkPnDArE

• A Randomized, Double-Blind, Placebo-Controlled Trial of Abatacept for the Treat…
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Gender differences in axSpA extend to dse activity assessment tools. PREDICT-SpA: 🔶️BASDAI score performed better in women. 🔶️ ASDAS-CRP homogenous performance on both genders. Consider BASDAI for assessing dse activity in women? @RheumNow #ACR24 abs571 @rheumarhyme https://t.co/rKJXn2EPXa

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👴🏼 Ageing & RMDs at #ACR24 🧠 14 factors associated with dementia ❗️Justin Levenson tells us that if we could address all of these, we could reduce dementia risk by 45%! @RheumNow https://t.co/SgC5KMohXy

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Nationwide US study -Prevalence of HLH in SLE: 0.13% -Higher risk in younger, female, and racial minority patients - Strong association with high mortality #ACR24 abst#0619 @RheumNow

Study on #AI-augmented remote care for SLE: - Combined biometric, self-reported, and NLP-extracted data - Moderate to strong correlations with physician global assessment - Potential to improve remote disease management - but now very accurate for now #ACR24 abst#0635 @RheumNow

Interim analysis of a Phase 4 study of ARD (RA 25%, SLE 25%) patients shows recombinant herpes zoster vaccine(RZV) good safety profile, with no impact on disease activity (flare rates: 13.6% vs. 12.4%). Immunogenicity: 93% response in ARDs vs. 99% in controls. Rituximab & MMF… https://t.co/U3s48fLduX https://t.co/WTvD5shtXB

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Study on socioeconomic factors in SLE hospitalizations - US wide data - No insurance & non-metro areas linked to shorter LOS, lower costs, higher mortality - Higher income & age increase charges - Targeted interventions needed to improve outcomes #ACR24 abst#0615 @RheumNow