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With many treatments for #PsA and #PsO, what are the prescribing trends?

Abstract 0604: TNF inhibitors remain the most

Akhil Sood MD AkhilSoodMD

1 year 9 months ago
With many treatments for #PsA and #PsO, what are the prescribing trends? Abstract 0604: TNF inhibitors remain the most common (~60%), but over the past 10 years, IL-17i use rose from 0.2% to 19%, and IL-23i from 0.1% to 39.7%! #ACR24 @RheumNow https://t.co/4TnCAkHfuY
Cannabis and Physical Function
Very small effects on meta-analysis

PO cannabis - 4% benefit (0.1-8%) of achieving at le

Eric Dein ericdeinmd

1 year 9 months ago
Cannabis and Physical Function Very small effects on meta-analysis PO cannabis - 4% benefit (0.1-8%) of achieving at least MID of SF36 function scale 16S18 @BharatKumarMD #ACR24 @RheumNow https://t.co/qQOYt1m3ub
For many years glucocorticoids were the mainstay of our treatment of granulomatosis with polyangiitis (GPA). The paradigm shifted with cyclophosphamide and then again with rituximab, and we used less steroids, but we still used lots. Avacopan teased the demise of steroids, but in the trial they, and now we, still use them. Glucocorticoids are our old trusty friend, our comfort blanket. But no more! Good riddance to the medication with the
Can multidisciplinary clinics improve quality of care for PsA?
Abstract 0596: Multidisciplinary care in PsA associated

Akhil Sood MD AkhilSoodMD

1 year 9 months ago
Can multidisciplinary clinics improve quality of care for PsA? Abstract 0596: Multidisciplinary care in PsA associated with ↓ time to first biologic, ↑ dermatology & nurse visits, and better CV risk assessment. #ACR24 @RheumNow https://t.co/2OnUR6te63
Pharmacologics:
Cannabis absorption and metabolism is variable
Inhaled absorption 10-35%
THC is 97% protein bound, lipo

Eric Dein ericdeinmd

1 year 9 months ago
Pharmacologics: Cannabis absorption and metabolism is variable Inhaled absorption 10-35% THC is 97% protein bound, lipophilic and deposits in fat and spleen Liver function is critical for THC metabolism 16S18 @BharatKumarMD #ACR24 @RheumNow
Quinn @KQuinnRheum @petercgrayson et al. FDG-PET is not particularly useful in monitoring GCA on tocilizumab. Toc reduce

Richard Conway RichardPAConway

1 year 9 months ago
Quinn @KQuinnRheum @petercgrayson et al. FDG-PET is not particularly useful in monitoring GCA on tocilizumab. Toc reduces but often not eliminate PET inflammation. PET activity does not predict relapse or vascular progression @RheumNow #ACR24 Abstr#0742 https://t.co/1qcJCGV118 https://t.co/6mBCgcbYo6
Prevalence of HLH among pts w/SLE: lower than consults would suggest!

Observational study using NIS: 139 cases out of

Mike Putman EBRheum

1 year 9 months ago
Prevalence of HLH among pts w/SLE: lower than consults would suggest! Observational study using NIS: 139 cases out of >100k pts w/SLE (0.13%); 6 fold increase in mortality Fits my priors; HLH is overdiagnosed, but bad when it happens @RheumNow #ACR24 Abstr#0619 https://t.co/iz3BlUOJb9
#Abstract0649
Acetylated albumin at K402 as a possible predictor for newly diagnosed lupus nephritis, distinguishing inc

Akhil Sood MD AkhilSoodMD

1 year 9 months ago
#Abstract0649 Acetylated albumin at K402 as a possible predictor for newly diagnosed lupus nephritis, distinguishing incident LN from SLE, treated LN & healthy controls. @RheumNow #ACR24 https://t.co/aCRzt9TtoK
Harkins @DrTrishHarkins et al. Serum disease activity markers in PMR. ROC analysis for active vs remission - fibrinogen

Richard Conway RichardPAConway

1 year 9 months ago
Harkins @DrTrishHarkins et al. Serum disease activity markers in PMR. ROC analysis for active vs remission - fibrinogen (1.000), ESR (0.986), Haptoglobin (0.976), CRP (0.986), ALP (0.854). @RheumNow #ACR24 Abstr#0741 https://t.co/f8cX68Ov9Y https://t.co/zp5c7aQwxr
#0066
🧬Epigenetics, Gut Microbiota & RA

🔬 110 RA patients v 110 controls

🦠 Collinsella abundance a/w DNA

Caoilfhionn Connolly CaoilfhionnMD

1 year 9 months ago
#0066 🧬Epigenetics, Gut Microbiota & RA 🔬 110 RA patients v 110 controls 🦠 Collinsella abundance a/w DNA methylation changes (PRHOXNB, TBC1D22A) in RA, correlating with disease activity. 💡❔Role of gut microbiota & epigenetic markers as RA biomarkers #ACR24 @RheumNow https://t.co/yZn0KkRpE6
Is biologic response different in men vs women with axSpA?

A Meta-analysis of 11 studies including 11,199 axSpA pts eva

Adela Castro AdelaCastro222

1 year 9 months ago
Is biologic response different in men vs women with axSpA? A Meta-analysis of 11 studies including 11,199 axSpA pts evaluated sex-related response to bDMARDs -Male pts more likely to achieve BASDAI 50 and ASDAS low disease activity responses compared to females. #Abst0599… https://t.co/FopBLS4bF6 https://t.co/PpoZB9HwZN
Dunn et al. Are the medications recommended for RA-ILD by the ACR guidelines used in the real-world. NO! 4108 RA-ILD pat

Richard Conway RichardPAConway

1 year 9 months ago
Dunn et al. Are the medications recommended for RA-ILD by the ACR guidelines used in the real-world. NO! 4108 RA-ILD patients. Only 12% on one of the first line recommended therapies! @RheumNow #ACR24 Abstr#0214 https://t.co/OzW90OA1Vd https://t.co/S1MKmEDrLF
The METEOR study reveals distinct clinical features in spondyloarthritis (SpA) patients with vs. without IBD.

Key feat

Antoni Chan MD (Prof) synovialjoints

1 year 9 months ago
The METEOR study reveals distinct clinical features in spondyloarthritis (SpA) patients with vs. without IBD. Key features of those with IBD: - Lower male prevalence - Higher uveitis rates - Lower psoriasis rates - More structural damage in SI joints Mirroring gut… https://t.co/EyBZQ91DDn
Another abstract #0650 highlighting the impact of tubulointerstitial inflammation predicting risk of CKD/ESRD in lupus n

Akhil Sood MD AkhilSoodMD

1 year 9 months ago
Another abstract #0650 highlighting the impact of tubulointerstitial inflammation predicting risk of CKD/ESRD in lupus nephritis @RheumNow #ACR24 https://t.co/XYwO0xnWNR
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