Smoking and Rx progression in PsA? -Prospective Canadian cohort of 1736 PsA pts. -Older age, BL SJC, dactylitis, erosions and high ESR were associated with Rx progression. 🚨Cigarette smoking did not appear to be associated with the Rx progression in PsA. Abst#1436 #ACR24… https://t.co/J2IogqOlx8 https://t.co/U6SRmbOE6o

• https://x.com/i/web/status/1858208485722255551
• https://x.com/AdelaCastro222/status/1858208485722255551/photo/1

Study on severe lymphopenia in SLE: - Assessed incidence, risk factors, and outcomes - 11.52% of SLE patients experienced severe lymphopenia - Higher infection rates during severe lymphopenia period = No opportunistic infections observed #ACR24 abst#1519 @rheumnow @HSSProfEd

Study on pregnancy outcomes in SLE with thrombocytopenia: Higher disease activity, pregnancy loss, and stillbirth rates Identified risk factors: Anti-β2GP-I positivity and higher SLEDAI score #ACR24 abst#1487 @RheumNow

Study on cardiovascular deaths in SLE: - Analyzed 1999-2020 data - Overall decline in mortality rates, but recent increase since 2014 - Higher rates in women and African Americans - Geographic disparities noted #ACR24 abst#0998 @rheumnow https://t.co/dpjsl0gI0x

• https://x.com/bella_mehta/status/1858209991041466428/photo/1
• https://x.com/bella_mehta/status/1858209991041466428/photo/1

Post hoc analysis of INVIGORATE-1 trial evaluated predictors of ASAS40 response in axSpA pts who received IV SEC ⬆️back pain, long dse duration, ⬇️BMI: assoc w/ ⬆️ clinical response BL enthesitis, older age, ⬆️dse activity: assoc w/ ⬇️ clinical response @RheumNow #ACR24 abs1482 https://t.co/528A5lXVKl

• https://x.com/RHEUMarampa/status/1858210259434897823/photo/1
• https://x.com/RHEUMarampa/status/1858210259434897823/photo/1

#Upadacitinib rises ‘ Up’ in all subgroups of #GCA Subset of overall #RCT of #rinvoq w more reduction of #steroids vs placebo+ slower #prednisone taper Consistent results best in UPA 15 mg >UPA 7.5mg/d > #placebo #ACR24 #ACRBest @RheumNow @ACRheum abst#1695 https://t.co/dA7RkNmWFd

• https://x.com/Janetbirdope/status/1858210971937841222/photo/1

RheumNow’s expanded coverage of the #ACR24 annual meeting is sponsored in part by Bristol Myers Squibb and UCB. All content is chosen by RheumNow and its faculty.

Salivary glands in #Sjogens #Disease Have persistent #IFN signature Abnormal morphology ⬇️ secretory ability In Differentiated salivary gland organoids DSGO May aid in drug screening Would drugs that ⬇️ #interferon help #Sjogren’s Abst#1406 @RheumNow @ACRheum #ACR24 https://t.co/dppp0tyFk5

• https://x.com/Janetbirdope/status/1858202665211089048/photo/1

Alright help me out here; this is pretty implausible, right? Why would be pts be 11% more adherent to UPA? What's the bio-plausibility here? UPA 10% better than other JAKs? Could do a network meta analysis; betting this doens't replicate #ACR24 @RheumNow Abstr#1362 https://t.co/vpPq3vu9Wf

• https://x.com/EBRheum/status/1858196904494186816/photo/1
• https://x.com/EBRheum/status/1858196904494186816/photo/1

#Rheumatoid #arthritis is an independent risk factor for death in nonmetastatic clear cell renal ca ! 👇N=32K, 802 w RA also Caveats immunotherapy Offered = in RA Cancer specific mortality not affected By #RA Frailty & RA affected outcomes #ACR24 @RheumNow @ACRheum #1327 https://t.co/rAQ57BPA19

• https://x.com/Janetbirdope/status/1858197735205188060/photo/1

The Joint Project is a community-based, barangay health worker-led screening program that aims to increase MSK dse awareness, timely referral & treatment or rehab. The figure below illustrates the conceptual framework for the program @RheumNow #ACR24 abs0979 https://t.co/yxXsASl2GJ

• https://x.com/RHEUMarampa/status/1858198191830700125/photo/1

This study by Dr. UGazel et al shows that cervical DISH in SpA is similar to the general population. Of note, HLAB27+ axSpA pts had more DISH while PsA pts had DISH if they were HLaB27(-) @RheumNow #ACR24 abs1447 https://t.co/GtcvxVSb8B

• https://x.com/RHEUMarampa/status/1858199028069961871/photo/1

Gonzalez Molina et al. MANHATTAN observational study. In PsA after 1st TNFi failure should we use guselkumab or 2nd TNFi? Guselkumab slightly better persistence, DAPSA, and improvements in joint counts. @RheumNow #ACR24 Abstr#1469 https://t.co/X3TMCVys6B https://t.co/vvkUYbzVDq

• Manhattan Study: Observational, Ambispective Study to Describe Persistence and …
• https://x.com/RichardPAConway/status/1858194388360282291/photo/1

Ultrasound guided injections on cadavers improve rheumatology trainees ability to do #joint #injections 17 trainees -a couple of hrs of cadaver inj ▶️ joint injection confidence improved esp uncommon / difficult areas Elbow Ankle Wrist @RheumNow #ACR24 @ACRheum abst#1310 https://t.co/ZcER4s8QcR

• https://x.com/Janetbirdope/status/1858195483681816832/photo/1

No Increase in Cardiovascular Events with JAK Inhibitors in IBD Patients UMKC researchers have compared the use of JAK inhibitors versus tumor necrosis factor (TNF) blockers in inflammatory bowel disease (IBD) patients, but failed to see an increase in major adverse… https://t.co/IOzckJIfYf https://t.co/8S6FnffVLG