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Mindfulness in Managing Chronic Pain

JAMA reports that outpatient resource mindfulness-based interventions (MBIs) deli

Dr. John Cush RheumNow

1 year 10 months ago
Mindfulness in Managing Chronic Pain JAMA reports that outpatient resource mindfulness-based interventions (MBIs) delivered via telehealth are effective in managing chronic pain amongst veterans. https://t.co/ytSb03h0Fd https://t.co/vWKvYW9Udb
Artificial Intelligence in Diagnosing Sacroiliac Inflammation in axSpA

A so-called deep learning artificial intelligen

Dr. John Cush RheumNow

1 year 10 months ago
Artificial Intelligence in Diagnosing Sacroiliac Inflammation in axSpA A so-called deep learning artificial intelligence (AI) algorithm for analyzing MRI scans showed "acceptable" agreement with expert human readers for detecting sacroiliac joint (SIJ) inflammation in patients… https://t.co/nKbYF603ut https://t.co/Y5IzVIG2l3
Mucosal Disruptions as Initiators of Rheumatoid Arthritis

The microbiome and mucosal disruptions are believed to play

Dr. John Cush RheumNow

1 year 10 months ago
Mucosal Disruptions as Initiators of Rheumatoid Arthritis The microbiome and mucosal disruptions are believed to play a role in autoimmunity, particularly rheumatoid arthritis (RA). This is linked to the "mucosal hypothesis" of RA. A recent review by Hollers, et al. discusses… https://t.co/79khnkajMy https://t.co/UvZWwJ3ERg
A prospective Scleroderma Cohort Study found that gastrointestinal tract (GIT) involvement was common and negatively impacted quality of life, physical function, and employment, but had no effect on mortality. 
Analgesic Prescribing in Patients with Inflammatory Arthritis

A UK cross-sectional EHR clinical practice analysis betw

Dr. John Cush RheumNow

1 year 10 months ago
Analgesic Prescribing in Patients with Inflammatory Arthritis A UK cross-sectional EHR clinical practice analysis between 2004 and 2020 shows that analgesic prescribing in inflammatory arthritis (IA) patients has declined, but still remains substantial, including opioid… https://t.co/K43YERU3rf https://t.co/DRZ4r9JDSv
JCI article on Mechanisms underlying sex differences in autoimmunity - factors include sex hormones, X chromosome genes,

Dr. John Cush RheumNow

1 year 10 months ago
JCI article on Mechanisms underlying sex differences in autoimmunity - factors include sex hormones, X chromosome genes, sex-specific epigenetic effects of estrogen & environment, and microRNA effects. Also mitochondria & autoantibodies discussed https://t.co/hTrizE8jFK https://t.co/VixAZsYBzb
Appraisal of 2023 ACR RA-ILD guidelines (based on only 3 RCTs). Conditional Recs for MMF, AZA, RTX as 1st-line RA-ILD Rx

Dr. John Cush RheumNow

1 year 10 months ago
Appraisal of 2023 ACR RA-ILD guidelines (based on only 3 RCTs). Conditional Recs for MMF, AZA, RTX as 1st-line RA-ILD Rx. W/ RA-ILD progression, options include MMF, RTX, nintedanib, TCZ, CTX, & pirfenidone are conditionally recommended https://t.co/9M3XykPQIi https://t.co/S0TMCsVd4y
French cohort study shows that epidermal necrolysis (EN) is a rare, but assoc w/ high rates of in-hospital and postdisch

Dr. John Cush RheumNow

1 year 10 months ago
French cohort study shows that epidermal necrolysis (EN) is a rare, but assoc w/ high rates of in-hospital and postdischarge mortality, esp in elderly and those w/ comorbid conditions. https://t.co/BaMZmer0Fa https://t.co/mrUO419GLP
Waiting more than 4 hours in emergency care for treatment is linked to heightened risks of death and a longer hospital stay for hip fracture patients, reveals a single centre study, published online in Emergency Medicine Journal.
JAMA reports that outpatient resource mindfulness-based interventions (MBIs) delivered via telehealth are effective in managing chronic pain amongst veterans.The challenge of mindfulness interventions is often the access, availability and dedicated space for trained instructors.
A so-called deep learning artificial intelligence (AI) algorithm for analyzing MRI scans showed "acceptable" agreement with expert human readers for detecting sacroiliac joint (SIJ) inflammation in patients with axial spondyloarthritis (axSpA), researchers said.
Stop Counting Bugs (10.4.2024)

This week’s rants include the microbiome, PsA treatment choices and fishing for P-val

Dr. John Cush RheumNow

1 year 10 months ago
Stop Counting Bugs (10.4.2024) This week’s rants include the microbiome, PsA treatment choices and fishing for P-values in research. https://t.co/KRoMltgPeM https://t.co/9uAbqV8PDK
Genomic profiling of 34 ANCA-assoc vasculitis pts w/ glomerulonephritis suggests activity by cytokine-producing CD4+ &am

Dr. John Cush RheumNow

1 year 10 months ago
Genomic profiling of 34 ANCA-assoc vasculitis pts w/ glomerulonephritis suggests activity by cytokine-producing CD4+ & CD8+ T cells & potential for ustekinumab. 4 relapsing GN pts Rx w/ UST & CTX +steroids, w/ good responses, improved GFR and BVAS scores… https://t.co/ospA8CJ6JE https://t.co/HbRpXMec0f
Many have suggested that microbiome and mucosal disruptions are contributors to autoimmunity, especially rheumatoid arthritis (RA). This is partly represented in what is known as the "mucosal hypothesis" to RA. A current review article by Hollers, et al. addresses how distinct mucosal endotypes can serve as drivers or initiators of RA.
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