Harkins @DrTrishHarkins et al. Serum disease activity markers in PMR. ROC analysis for active vs remission - fibrinogen (1.000), ESR (0.986), Haptoglobin (0.976), CRP (0.986), ALP (0.854). @RheumNow #ACR24 Abstr#0741 https://t.co/f8cX68Ov9Y https://t.co/zp5c7aQwxr

• Serum Markers of Disease Activity in Polymyalgia Rheumatica - ACR Meeting Abstr…
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#0066 🧬Epigenetics, Gut Microbiota & RA 🔬 110 RA patients v 110 controls 🦠 Collinsella abundance a/w DNA methylation changes (PRHOXNB, TBC1D22A) in RA, correlating with disease activity. 💡❔Role of gut microbiota & epigenetic markers as RA biomarkers #ACR24 @RheumNow https://t.co/yZn0KkRpE6

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Is biologic response different in men vs women with axSpA? A Meta-analysis of 11 studies including 11,199 axSpA pts evaluated sex-related response to bDMARDs -Male pts more likely to achieve BASDAI 50 and ASDAS low disease activity responses compared to females. #Abst0599… https://t.co/FopBLS4bF6 https://t.co/PpoZB9HwZN

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Dunn et al. Are the medications recommended for RA-ILD by the ACR guidelines used in the real-world. NO! 4108 RA-ILD patients. Only 12% on one of the first line recommended therapies! @RheumNow #ACR24 Abstr#0214 https://t.co/OzW90OA1Vd https://t.co/S1MKmEDrLF

• Real-World Treatment Patterns of Clinical Practice Guideline Therapies in Rheum…
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The METEOR study reveals distinct clinical features in spondyloarthritis (SpA) patients with vs. without IBD. Key features of those with IBD: - Lower male prevalence - Higher uveitis rates - Lower psoriasis rates - More structural damage in SI joints Mirroring gut… https://t.co/EyBZQ91DDn

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Another abstract #0650 highlighting the impact of tubulointerstitial inflammation predicting risk of CKD/ESRD in lupus nephritis @RheumNow #ACR24 https://t.co/XYwO0xnWNR

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RheumNow’s expanded coverage of the #ACR24 Annual meeting is sponsored in part by Bristol Myers Squibb and UCB. All content is chosen by RheumNow & its faculty.

IV or inhaled THC: Works quickly with high peak, feel euphoric but not sustained response Oral is much better for medicinal usage @RheumNow #ACR24 https://t.co/3PatgEFjZh https://t.co/wrrLMpfL5D

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Cool data from the JAK-POT study Have heard JAKs faster than TNF; perhaps not the case! If anything, TNFs outperformed the others in this study Trying not to over-read this, but supports my re-emerging preference for TNF #ACR24 @rheumnow Abstr#0501 https://t.co/NDyPwju3ds

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How to take cannabis? Do NOT rec inhaled - makes drug level go up high/fast, benefit for rec use but not for medicinal - bronchitis, ?oral cancer Other risks: psychosis - risk in youth, memory loss (poor studies), dependence, respiratory if inhaled Clauw 16S18 #ACR24 @RheumNow https://t.co/coYNl7VOT3

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#0513 🔬 Rituximab in RA: IgG levels & infection ➡️ 164 patients (mean age 59, IgG 14g/L, dx duration 13yrs) 🧬 IgG levels ⬇️over time (6 years/25 infusions) ⚠️ Infection-related hospitalizations peaked year 1 ⬆️risk w/ concurrent steroid(HR 2.1,p=0.002) #ACR24 @RheumNow

Older adults with RA receive less DMARDs, the standard of care. Dr. Bruno Fautrel shows TOC tolerance in older adults is comparable to younger patients. Let's treat the patient, not their age! #ACR24 @RheumNow ABST#0516 https://t.co/054RWGh3a7

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Discrimination in #SLE is a chronic stressor - Asians had substantial levels along with association of worse mental health and SLE activity Data from the California Lupus Epidemiology Study (CLUES) using the Everyday Discrimination Scale (EDS) @JYazdany @RheumNow #ACR24 abst#0171

Clauw: think of THC and CBD as “completely different” Cannabidiol - safe, not psychoactive, “can use liberally” THC - psychoactive with effects on CB1 and CB2 receptors. CB1 affects the brain where CB2 is more in inflammation #ACR24 @RheumNow https://t.co/A0TgSpAO64

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