Congrats to 2024 recipients of the Lupus Research Alliance Diversity in Lupus Research Awards: - Carlos Castrillon PhD, Emory - Paul Hoover MD, PhD, Brigham - Renita Horton PhD, U Houston - Rodrigo Cervantes-Díaz PhD, Boston Childrens - Jonathan Lagos Orellana MD PhD, Seattle… https://t.co/gtvT4kt7Lt https://t.co/MOdxH2cPM1

2612 BSRBR-RA Registry pts on tocilizumab - increasing Body weight was associated with reduced DAS28 response to SC tocilizumab. But the DAS28 difference was small, and did not change drug persistence https://t.co/eR7kmjRaEE https://t.co/vFKYC1I3pV

• Association between body weight and tocilizumab effectiveness in rheumatoid art…

Chinese study of 62 Systemic JIA pts Rx w/ IV Tocilizumab (34 12 mg/kg; 28 8 mg/kg). Wk12 87% responded (JIA ACR 30w/ no fever); Week 52 results were similar. No deaths or macrophage activation syndrome occurred. https://t.co/qGgMCt597x https://t.co/lFDxAgDHfW

• Disease activity score for still’s disease

Swedish population/registry study of incidence of Psoriatic arthritis was estimated at 21.8/100 000 person-years (15.78-28.83/100 000 PY); slightly higher in females, lower w/ higher education, peaks 50-59y. 71% were on DMARD w/in 2 yrs (22% b/ts DMARDs) https://t.co/YTNBHczZ7X https://t.co/KNscF08fKG

• Incidence of clinically diagnosed psoriatic arthritis in Sweden

Retrospective Taiwan's Health claims: studied 6408 RA pts, half HCQ users vs non-users. No higher risk of osteoporosis in HCQ users vs non-users (aHR=0.99; 95% CI: 0.82–1.196). Why study this? HCQ may suppress both bone formation/resorption https://t.co/xShLXMElnH https://t.co/lkvihaYuAd

• Hydroxychloroquine and risk of osteoporosis in patients with rheumatoid arthrit…

Different Autoantibody Phenotypes in Juvenile and Adult Myositis A Kyoto University study compared juvenile-idiopathic inflammatory myopathy (IIM) and adult-IIM patients, demonstrating different autoantibody profiles and a more favorable outcome for n juvenile-IIM patients.… https://t.co/fHL14rXAQ6 https://t.co/ZagRU62joJ

Systemic Sclerosis Insights (9.13.2024) https://t.co/fRbKdSAqxG https://t.co/PMbYDXPHMd

• Systemic Sclerosis Insights (9.13.2024) | RheumNow

Congratulations to UCF Associate Professor Justine Tigno-Aranjuez for receiving prestigious U.S. National Science Foundation CAREER Award on her research into NOD2 receptor signaling of lipid mediators contributing to inflammation https://t.co/AkUZbdTSqF https://t.co/usTe2bzyXE

• Med school scientist receives prestigious NSF award for inflammation research

24 wk RCT of 683 chronic neck pain pts -acupuncture was more effective in reducing neck pain than sham or waiting (observation), but the magnitude of benefit was below the minimal clinically important change. https://t.co/sqNV8XFYRl https://t.co/hI5Y3z6JiK

• Long-Term Effects of Individualized Acupuncture for Chronic Neck Pain: A Random…

“Big doors swing on little hinges.” - W. Clement Stone https://t.co/wLfKpwUxzc

1,717 Chinese rheumatologists (92% response) surveyed on Steroid use in RA. 60% admit to infrequent use of GC cotherapy. Bridging GC use was supported (35%), opposed (27%), but 38% were inconclusive & 67% said long-term low-dose GC use depends on the pt https://t.co/7qe1aRsZx8 https://t.co/D0RoYxPohY

• Current practice, trends and attitudes of rheumatologists towards glucocorticoi…

Animal model shows Aggregatibacter actinomycetemcomitans periodontitis can trigger macrophage/caspase-11/inflammasome activation leading to paw swelling in mice anti-collagen antibody-induced arthritis (CAIA) model https://t.co/f41r28g5yr https://t.co/61NeXgfzmB

• Caspase-11 mediated inflammasome activation in macrophages by systemic infectio…