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Fantastic presentation from @MiaRodziewicz using BILAG-BR data:

⭐️NPSLE had higher damage / disease activity
⭐?

Sarah Dyball sarahdyball1

2 years 4 months ago
Fantastic presentation from @MiaRodziewicz using BILAG-BR data: ⭐️NPSLE had higher damage / disease activity ⭐️ NPSLE more likely to have APS ab ⭐️ RTX appears effective in NPSLE (no trials) https://t.co/25984cORj0
Great results presented at #EULAR24 by Greg Dresler on CD19/BCMA CAR T-cell therapy. 18 additional SLE patients with gre

Anne Troldborg TroldborgAnne

2 years 4 months ago
Great results presented at #EULAR24 by Greg Dresler on CD19/BCMA CAR T-cell therapy. 18 additional SLE patients with great response. ⁦@LUPUSDK⁩ ⁦@LupusEurope⁩ https://t.co/2C64ECzq83
Another excellent oral presentation from UPMC myositis center by Shiri Keret at #EULAR2024. She showed that many myositi

Rohit Aggarwal docrota

2 years 4 months ago
Another excellent oral presentation from UPMC myositis center by Shiri Keret at #EULAR2024. She showed that many myositis patient may have normal CK despite muscle weakness. However, CK is associated with outcomes over time even in patients with normal or near normal CK,… https://t.co/nAoUo8fcXh https://t.co/J8iZG4eESP
✅ Updated pipeline of phase 2 & 3 trials in #Lupus ⬇️ #EULAR2024
Please let me know if something is missing or

Laurent ARNAUD Lupusreference

2 years 4 months ago
✅ Updated pipeline of phase 2 & 3 trials in #Lupus ⬇️ #EULAR2024 Please let me know if something is missing or incorrect 👍 https://t.co/ruuKYmAvYj
John H Stone’s #IgG4RD lessons:
1-It is a variable-vessel vasculitis
2-more common/severe in males (2:1)
3-Has no diag

Vasco C Romao romaovc

2 years 4 months ago
John H Stone’s #IgG4RD lessons: 1-It is a variable-vessel vasculitis 2-more common/severe in males (2:1) 3-Has no diagnostic histopathology 4-IgG4 does not cause IgG4RD 5-Serum igg4 is a good biomarker 6-Rising IgG4 shouldn’t be ignored #EULAR2024 https://t.co/7p6pBqI4ue
RA specific bone signatures (markers) detected by machine learning. Abst#0125
Dkk1 increased in erosive RA #EULAR2024 @

Bella Mehta bella_mehta

2 years 4 months ago
RA specific bone signatures (markers) detected by machine learning. Abst#0125 Dkk1 increased in erosive RA #EULAR2024 @RheumNow https://t.co/0A5C9LCzle
Fibroblasts activated -> secrete chemokines which lead to granzyme K production inturn leading to damage to mitochon

Bella Mehta bella_mehta

2 years 4 months ago
Fibroblasts activated -> secrete chemokines which lead to granzyme K production inturn leading to damage to mitochondria - release of mitochondrial DNA and production of interferon type 1 which ultimately lead to infiltrates (which contribute to the worsening saliva production) https://t.co/jZkU3SBhwc
Single cell analysis with 12 groups
Those patient without lymphocytic infiltrates were different!
Mitochondria were the

Bella Mehta bella_mehta

2 years 4 months ago
Single cell analysis with 12 groups Those patient without lymphocytic infiltrates were different! Mitochondria were the differentiator in these patients. Fibroblasts and CD8+ T cells are the most actively communicating cells. - Chemokines and ECM https://t.co/Pe0WSoYdXT
🗣️Lowering glucocorticoids dose remains a key goal in #lupus management

Prof @EricFMorand at #EULAR2024

#letpush

Matteo Piga RMD_clinic

2 years 4 months ago
🗣️Lowering glucocorticoids dose remains a key goal in #lupus management Prof @EricFMorand at #EULAR2024 #letpushbelow5 mg of prednisone in #SLE https://t.co/IeiLh2zVrT
#EULAR2024

Reminder …
🔺Anti-drug antibodies cause significant variability in Therapeutic drug levels

🔺10% ha

Dr Gurdeep S Dulay gurdeep_dulay

2 years 4 months ago
#EULAR2024 Reminder … 🔺Anti-drug antibodies cause significant variability in Therapeutic drug levels 🔺10% have undetectable drug level after 3 months of Rx 🔺is therapeutic drug monitoring is beneficial? 🤔 https://t.co/ChgMnKPyFb
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