Dr. John Cush RheumNow
2 years 3 months ago
“50% of pts with lupus nephritis are asymptomatic . You have to have a degree of kidney damage before you have proteinuria. Proteinuria does not correlate with intrarenal activity.” – Dr. A Fava #RNL2024 @rheumnow https://t.co/UOC8MZDM8N
Dr. John Cush RheumNow
2 years 3 months ago
Danish registry study shows positive association between maternal autoimmune Dz & childhood cancer. AID assoc w/ all child CA (OR=1.25), ALL (1.52), Burkitts (2.69), CNS tumors (1.45). RA mothers AID had higher risk of all cancers (OR=2.1) https://t.co/EYHyHzOboc https://t.co/FNRrvySI8P
Patients with rheumatoid arthritis (RA) all have a unique and diverse set of antibodies that are involved in the development of the disease. Researchers at Utrecht University unveiled the complexity of these antibodies using powerful lab tools capable of analysing our immune system at molecular levels.
Analysis of the German RABBIT registry shows that systemic inflammation, more so than disease activity, strongly influences all-cause mortality in patients with rheumatoid arthritis and prevalent interstitial lung disease (RA-ILD).
Dr. John Cush RheumNow
2 years 3 months ago
Dr. Gabalawy: "How do you know what disease patients will develop in this preclinical autoimmunity state?"
@drdavidkarp ""it's like when weeds pop up in a garden, it's random ...if ACPA Ab pops up, you might have RA, if it's dsDNA, maybe lupus."" #RNL2024 https://t.co/kDkDaDRP8X
Dr. John Cush RheumNow
2 years 3 months ago
Low urinary IL16 levels at 12 months predicts kidney survival at 3 years better than proteinuria - @Andreafava @rheumnow #RNL2024 https://t.co/4GLmJQr46C
Dr. John Cush RheumNow
2 years 3 months ago
Rheum Chapter Notes
Dr. Jack Cush reviews this past week’s news and journal articles from https://t.co/V10S4oVFsv.
https://t.co/m6pkmYeiAl https://t.co/3cr3KwV1CP
Dr. John Cush RheumNow
2 years 3 months ago
UK Early Inflammatory Arthritis Audit of 20,060 RA pts (~12k on MTX; 5K csDMARD; ~2.5K no DMARD). Serious infections (SIE) hosp rate was 3.19/100PY, death 0.1/100PY. SIE risk incr w/ age, smoking, Hi DAS28 & HAQ. 1 unit DAS28, SI risk increased by 8% https://t.co/OrNh8oYE3y https://t.co/DqbeibNMbp
Dr. John Cush RheumNow
2 years 3 months ago
Tuesday Night Rheumatology: Mastering SLE https://t.co/lhExjSsKNA
Dr. John Cush RheumNow
2 years 3 months ago
FDA issued a drug safety warning linking thiopurine (AZA, 6MP) use in pregnancy & a rare risk of intrahepatic cholestasis of pregnancy (ICP). ICP has been reported in pts w/ CD, UC, or SLE; however thiopurines are not FDA approved for these Dx https://t.co/XKoUdy4sAR https://t.co/DSU9z0v7CZ
Dr. John Cush RheumNow
2 years 3 months ago
British Society for Rheumatology (BSR) presented (at the 2024 annual BSR meeting) new guidelines for the management of Behçet's disease - how to manage skin lesions, mouth ulcers, genital ulcers, serious eye, CNS & vascular involvement https://t.co/d0bjKuubym https://t.co/lqoTeTGqZ7
Science Advances has reported that Duke University researchers have validated a biomarkers of osteoarthritis that may be identified 2 years before the appearance of radiographic OA.
In an open-label, randomized, non-inferiority trial, rheumatoid arthritis patients in remission were subject to tapering of disease-modifying antirheumatic drugs (DMARDs), and while maintenance of remission was seen in some, many DMARD tapering patients did flare and were unable to maintain flare-free survival compared to those on stable conventional synthetic DMARDs.
Dr. John Cush RheumNow
2 years 3 months ago
Spondyloarthritis Faculty Panel Q&A
Spondyloarthritis Faculty Panel Q&A - featuring Drs. Eric Ruderman, Lihi Eder, and Lianne Gensler; moderated by Dr. Artie Kavanaugh
https://t.co/6RFkyO72e1 https://t.co/CJ174sETFv
Dr. John Cush RheumNow
2 years 3 months ago
Future Therapy of Axial Spondyloarthritis
https://t.co/wjrlkuu0ds https://t.co/jQ12eTpT2l

