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QD Clinic - ANA Positivity in RA
Dr. Jack Cush imparts his new New Year's Resolutions for 2024 and also reviews the news and journal reports from the past week on RheumNow.com.
New Year's Resolutions (1.5.2024)
QD Clinic - Rituximab Dosing in RA
An ultrasound study suggests that enthesitis is associated with both synovitis and tenosynovitis in patients with Psoriatic arthritis (PsA).
Metanalysis of CNS Lupus, 44 studies, 17 865 early- (<50y) vs 2970 late-onset SLE (>50y) pts. CNS LE in 16%, more

Dr. John Cush RheumNow

2 years 7 months ago
Metanalysis of CNS Lupus, 44 studies, 17 865 early- (<50y) vs 2970 late-onset SLE (>50y) pts. CNS LE in 16%, more common in younger LE (OR: 1.41). Early-LE had more seizures (OR: 1.68), psychosis (OR: 1.72). Older - more Peripheral neuropathy (OR: 0.64) https://t.co/XoJjIH69t6 https://t.co/sRyV7A07gA
Biomarker Predicts Survival in Autoimmune Lung Disease

One major subgroup of patients with ILD arising from polymyosit

Dr. John Cush RheumNow

2 years 7 months ago
Biomarker Predicts Survival in Autoimmune Lung Disease One major subgroup of patients with ILD arising from polymyositis/dermatomyositis (PM/DM) survived significantly longer when serum levels of interferon-λ3 were relatively low, researchers found. https://t.co/9c9DjOIeoI https://t.co/fBpvjODybd
In Norway incidence of #SLE is decreasing, esp in women 50-59 years. Population study of 1558 confirmed SLE; 797 had n

Dr. John Cush RheumNow

2 years 7 months ago
In Norway incidence of #SLE is decreasing, esp in women 50-59 years. Population study of 1558 confirmed SLE; 797 had new-onset betw 1999-2017. In older women 50-59 yrs incidence fell 3.4 to 1.1/100K (also 74% reduction in menopausal HRT https://t.co/Z1falNwLlD https://t.co/bJ3cXKueKg
Poorly documented Dz activity in SpA. AI EHR analysis of 3 Hospitals found 758 pts (328 axSpA, 365 PsA, 65 non-classifi

Dr. John Cush RheumNow

2 years 7 months ago
Poorly documented Dz activity in SpA. AI EHR analysis of 3 Hospitals found 758 pts (328 axSpA, 365 PsA, 65 non-classified SpA). Only 35% axSpA had ASDAS or BASDAI. DAPSA or DAS-28 in only 17% PsA. TJC/SJC in ~20% axSpA & ~32% of PsA https://t.co/OrLdK5k2lN https://t.co/bKjancBG4r
Wallace et al. Dose, duration, recency dependent relationship between GC and MACE. Even 5mg/day, 30 day use, and use 1 y

Dr. John Cush RheumNow

2 years 7 months ago
Wallace et al. Dose, duration, recency dependent relationship between GC and MACE. Even 5mg/day, 30 day use, and use 1 year prior associated with risk. 5mg, 7.5mg, 10mg pred for 90 days - 13%, 19%, 27% MACE increase Abstr#2430 #ACR23 #ACRbest https://t.co/zJ9583vllj https://t.co/M1oKAcnqSH
QD Clinic - A Non-Textbook Patient
Curcumin is widely used in traditional Chinese medicine to treat arthritis and is presumed to have analgesic and antiinflammatory effects that may benefit those with osteoarthritis, particularly knee osteoarthritis (KOA). A network metanalysis was performed to gauge the efficacy and safety of curcumin, both alone and in combination with other drugs (eg, NSAIDs), in the treatment of KOA. 
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