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In case you needed any more reasons why @philseo is the best @rheum_cat , this is his first slide @RheumNow #RNL2024 ht

Richard Conway RichardPAConway

2 years 8 months ago
In case you needed any more reasons why @philseo is the best @rheum_cat , this is his first slide @RheumNow #RNL2024 https://t.co/Ar0v7sQuuX
Dr @anisha_dua's takehome points for treating GPA in 2024
*RTX and CYC are both effective followed by RTX at least 500mg

Dr. Rachel Tate uptoTate

2 years 8 months ago
Dr @anisha_dua's takehome points for treating GPA in 2024 *RTX and CYC are both effective followed by RTX at least 500mg q 6 mo for at least 2 years *PLEX not generally used, but may be effective in preventing ESKD *Rapid GC tapering may not be suitable for all pts *Avacopan is… https://t.co/haI19Sgpmu https://t.co/jhjXLwd0Uw
PJP prophylaxis in GPA. Always a trade off but these things are not created equal. PJP or sepsis are much worse on avera

Richard Conway RichardPAConway

2 years 8 months ago
PJP prophylaxis in GPA. Always a trade off but these things are not created equal. PJP or sepsis are much worse on average than the AEs @anisha_dua @RheumNow #RNL2024 https://t.co/9sECd7fSRk
Remission maintenance in AAV. First 2 years is clear - fixed dose RTX is superior. After that it is clear that following

Richard Conway RichardPAConway

2 years 8 months ago
Remission maintenance in AAV. First 2 years is clear - fixed dose RTX is superior. After that it is clear that following ANCA is suboptimal, could consider either B-cell return dosing or ongoing fixed dosing @anisha_dua @RheumNow #RNL2024 https://t.co/0Elir88L9U
Maintenance issues in GPA. Clear messages. 1. RTX is best 2. Fixed 6-monthly RTX best for 1st 2 years. 3. Don't stop RTX

Richard Conway RichardPAConway

2 years 8 months ago
Maintenance issues in GPA. Clear messages. 1. RTX is best 2. Fixed 6-monthly RTX best for 1st 2 years. 3. Don't stop RTX at 2 years! @anisha_dua @RheumNow #RNL2024 https://t.co/jS3jWm0CcS
The answer to "always" is "always" no, correct? PEXIVAS low dose is a great baseline plan, but always adjust in light of

Richard Conway RichardPAConway

2 years 8 months ago
The answer to "always" is "always" no, correct? PEXIVAS low dose is a great baseline plan, but always adjust in light of the individual patient both upfront and especially if things aren't working out @anisha_dua @RheumNow #RNL2024 https://t.co/RPnpAdB1eG
Rapid GC taper in ANCA vasculitis
#RNL2024 @RheumNow
@anisha_dua
PEXIVAS - reduced GC is safe, decreased ifns
Retrospe

Eric Dein ericdeinmd

2 years 8 months ago
Rapid GC taper in ANCA vasculitis #RNL2024 @RheumNow @anisha_dua PEXIVAS - reduced GC is safe, decreased ifns Retrospective real world - 234 pts. Reduced dose GC+RTX increased death/ESKD HR 2.42. No difference in infections https://t.co/SWIUSyVbWb
Great talk @anisha_dua re:AAV, solid updates on mgmt decisions

Looking forward to debating this study with @lastwalsh w

Mike Putman EBRheum

2 years 8 months ago
Great talk @anisha_dua re:AAV, solid updates on mgmt decisions Looking forward to debating this study with @lastwalsh w/@MatsJunek moderating... @TerrierBen any updates on when your RWD study will be published? @RheumNow https://t.co/ywVaOIp2WJ
"Real world studies: When people stop being polite and start getting real." Dr @anisha_dua #RNL2024
Comparing Walsh to

Dr. Rachel Tate uptoTate

2 years 8 months ago
"Real world studies: When people stop being polite and start getting real." Dr @anisha_dua #RNL2024 Comparing Walsh to Nagle in terms of primary outcomes, regimens, pt populations, and plasma exchange. @RheumNow https://t.co/io8OGnWxdS
Is there data for PLEX in GPA?
@anisha_dua #RNL2024 @RheumNow
PEXIVAS negative study
But subgroups show decreased dialy

Eric Dein ericdeinmd

2 years 8 months ago
Is there data for PLEX in GPA? @anisha_dua #RNL2024 @RheumNow PEXIVAS negative study But subgroups show decreased dialysis... But, no improvement in mortality and increased infection risk https://t.co/K9VbcNNsge
#RNL2024 @RheumNow
@anisha_dua
Throwing the kitchen sink in severe GPA
CYC + RTX combo - sick population (median GFR

Eric Dein ericdeinmd

2 years 8 months ago
#RNL2024 @RheumNow @anisha_dua Throwing the kitchen sink in severe GPA CYC + RTX combo - sick population (median GFR 9, 47% on HD, 52% DAH, all received PLEX too) - 85% survival, 69% not ESKD, low rates of relapse (13% at 36 mos) But, prolonged B cell depletion, aggressive Rx https://t.co/9AZFMQ3o9P
#RNL2024 is up and at ‘em this Sunday morning! ⁦@RheumNow⁩ ⁦@KDAO2011⁩ ⁦@RichardPAConway⁩ ⁦@ericdeinmd?

Dr. Rachel Tate uptoTate

2 years 8 months ago
#RNL2024 is up and at ‘em this Sunday morning! ⁦@RheumNow⁩ ⁦@KDAO2011⁩ ⁦@RichardPAConway⁩ ⁦@ericdeinmd⁩ https://t.co/AtL9QiRnW4
@anisha_dua reviews GPA management in 2024. Here are your ACR/VF 2021 and EULAR 2022 guideline updates. Review these reg

Dr. Rachel Tate uptoTate

2 years 8 months ago
@anisha_dua reviews GPA management in 2024. Here are your ACR/VF 2021 and EULAR 2022 guideline updates. Review these regimen options for your patients. #RNL2024 @RheumNow https://t.co/SvQoe0YKKV
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