Dr. John Cush RheumNow
2 years 8 months ago
Study compared 491 SLE pts tested for ANCA Abs w/ 171 ANCA-associated vasculitis (AAV) pts. 46 SLE pts were ANCA+. ANCA-positive LN have worse baseline renal function and lower protein remission rates . https://t.co/fQCkBXJpO4
Dr. John Cush RheumNow
2 years 8 months ago
200 Biologic naive #RA pts in remission under csDMARD tapering and withdrawal while given either placebo or oral curcumin (1 g bid). Flare-free survival at 52 wks was similar between groups (60% vs 64%; p = 0.76). Time to flare was similar (219d vs 214d) https://t.co/m3j8HmjTT3 https://t.co/jDoAYN0eKQ
Dr. John Cush RheumNow
2 years 8 months ago
SGLT2 Inhibitors as Gout Treatment. Patients with gout and type 2 diabetes treated with SGLT2 inhibitors not only had reduced numbers of gout flares, but also lived longer compared with other such patients receiving other medications, researchers said. https://t.co/zJVJuvCoIm https://t.co/kDLJynYczc
Dr. John Cush RheumNow
2 years 8 months ago
QD Clinic - Great Rheum Meetings
What makes for a great Rheumatology CME meeting?
https://t.co/tdb2crz8XP https://t.co/ZnMIhZpejO
Dr. John Cush RheumNow
2 years 8 months ago
RHEUMATOLOGIST SURVEY QUESTION - Is TYK2 part of the Janus Kinase family?
Click here to answer >> https://t.co/szffvXtwaS
Dr. John Cush RheumNow
2 years 8 months ago
Best of 2023: Time to Risk Stratify Methotrexate Lab Monitoring?
A longitudinal cohort analysis has developed a prognostic model that informs a risk stratified approach to monitoring blood tests during long term methotrexate (MTX) therapy.
https://t.co/WZcJugj3Bg https://t.co/HQ3Xg9h0md
NIH researchers have have described a novel autoinflammatory disorder called "Lyn kinase-associated vasculopathy and liver fibrosis" (LAVLI), based on a mutation in the LYN gene (that encodes the Lyn kinase protein). They discovered that increased Lyn kinase activity promotes systemic inflammation, by altering microvascular permeability and neutrophil recruitment, while at the same time promoting hepatic fibrosis.
The Cleveland Clinic Journal has published a full-read review of postural orthostatic tachycardia syndrome (POTS), a condition often seen in clinic with symptoms like fibromyalgia, but is clinically diagnosed with finding sustained tachycardia upon standing without orthostatic hypotension.
Dr. John Cush RheumNow
2 years 8 months ago
Best of 2023: 25 Great Women in Rheumatology
https://t.co/9WgGbpILGb https://t.co/YN8QAHtyab
Dr. John Cush RheumNow
2 years 8 months ago
NEJM - Clinical Images. Sleeve Sign and Inverse Gottron’s Papules in Anti-MDA5 Dermatomyositis. Erythematous plaques/patches on lateral aspects upper arms &; red patches, papules, pustules on ventral palms https://t.co/UHKGePi6TK
Dr. John Cush RheumNow
2 years 8 months ago
Livedo reticularis is a painless, cyanotic cutaneous mottling in a fishnet pattern, often on extremities > trunk & exaggerated by cold. NOT specific but may be assoc w/ fibromyalgia, Raynauds, atheromatous or autoimmune Dz, hyperviscosity, thrombotic Dz https://t.co/8tGz1hIDiA https://t.co/3mw2RwTEeL
Dr. John Cush RheumNow
2 years 8 months ago
- High mortality risk predictors in patients with anti-MDA5 dermatomyositis include:
- rapidly progressive interstitial lung disease
- anti-Ro52 antibody
- age > 57 years
(based on study of 126 MDA-5+ DM pts)
https://t.co/8bw1zpEOIh https://t.co/LKXMYtr7hU
Dr. John Cush RheumNow
2 years 8 months ago
DA Approves Canakinumab for Gout Flares The US FDA has approved canakinumab \ Ilaris\ for the treatment of gout flares in adults who cannot be treated with NSAIDs, colchicine, or repeated courses of corticosteroids. https://t.co/OX3wIajQtm https://t.co/tMDMc8ZKE8
Dr. John Cush RheumNow
2 years 8 months ago
Great content. Dr Andrea Fava will present this data and other research on lupus biomarkers at https://t.co/2dcFVgu8z6 on Jan 27, 2024. Can't wait! https://t.co/IOJIyDAmeG
