sheila
2 years 11 months ago
In this Ph2b RCT of TAK-279 (TYK2i), pts w/ PsA given 15mg & 30mg achieved an ACR20 response at wk 12 vs. PBO(53.3% and 54.2% vs 29.2%, both p = 0.002)
⬆️common TEAEs: Npharyngitis, URTI, headache & rash
#ACR23 ABSL12 @RheumNow https://t.co/T6swJgw6vE
sheila
2 years 11 months ago
Burden of flare & organ damage of SLE pts from the Asia Pacific cohort:
Prevalence of organ damage at BL - 39%
Incidence of damage accrual: ~58 per 1000PY
Pts w/ >=2 flares accrued damage
Flares independently⬆️risk of damage accrual
#ACR23 ABST2261 @RheumNow @rheumarhyme https://t.co/nW34sI9FdP
Dr. Antoni Chan
2 years 11 months ago
Auricular vagal nerve stimulation did not meaningfully improve RA disease activity. Further research of the novel intervention is required in RA, Baker MC, #ACR23 @RheumNow https://t.co/agLtRKdDTf
Leonard Calabrese LCalabreseDO
2 years 11 months ago
Kevin. Winthrop knocks it down on WHO is immunocompromised among rheumatic disease pts at Innovation Theater @CCalabreseDO #ACR23 @alhkim @AdamJBrownMD @ELittlejohnDO https://t.co/4hFtQgvaIf
Md Yuzaiful Md Yusof
2 years 11 months ago
#ACR23 Abstr#2332 We need to compliment the Complement #SLE. Post-hoc analysis of SOC + PBO from Dapirolizumab Phase 2 RCT showed reduced response in patients who flared with low complement levels vs normal or persistent activity. To consider as a stratifier @RheumNow https://t.co/BcN6ExLD0s

