Dr. John Cush RheumNow
2 years 11 months ago
Watch: Utility of AI and ChatGPT in Rheumatology
Dr. Kathryn Dao interviews Dr. Richard Stern at the 2023 ACR Convergence meeting in San Diego, CA. #ACR23
https://t.co/SH0TGAdvm8 https://t.co/RHu8bH9YOG
Eric Dein
2 years 11 months ago
TM86 #ACR23 @RheumNow
Auricular chondritis, arthritis, axonopathy, high inflamm. Initial Dx: RP
Exam: lymphadenopathy, erythema nodosum, TJC 36, SJC 4 (knees/ankles), decr sensation, asymm reflex, macular rash, nerve thicken
Skin bx: septal panniculitis wo vasc
Dx: leprosy https://t.co/P5QJArRDaA
Janet Pope
2 years 11 months ago
#Cardiovascular imaging will help to detect #cardiac abnormalities earlier@in #rheumatic #diseases. #ACR23 @RheumNow @ACRheum 14T118 https://t.co/QKCpLWtkUv
Meral K. El Ramahi, MD MeralElRamahiMD
2 years 11 months ago
🚩Adjunct therapy to treat vasculopathy of MDA5-DM
⭐️Botox heals digital ulcerations and improves Raynaud's (slide 1)
Dr. Katherine Shaw injects Botox for healing recalcitrant ulcerated Gottron's papules (example patient failed nifedipine, sildenafil, pentoxyfylline & while on… https://t.co/4XCvRrzeTL https://t.co/yxUCzS30W1
Bella Mehta bella_mehta
2 years 11 months ago
What do we know about IL1 drugs in #OA only a small few stidies prior to CANTOS .
COLCHCINE didnt seem to work
LoDoCO2 post hoc analysis may work? @RheumNow #ACR23 https://t.co/h4oVRppI5S
Aurelie Najm
2 years 11 months ago
Gene signature predicts RA trajectory during pregnancy:
Blood RNAseq *before* pregnancy
🚺 improve during preg: Strong Neutrophil signature
🚺 experience dis worsening:
Strong B cell signature
Needs replication but could have major implications!
@RheumNow #ACR23 ABST2481 https://t.co/gOHwEvOOM6
Md Yuzaiful Md Yusof
2 years 11 months ago
#ACR23 Abstr# 2487 How to reduce PBO response in #SLE trials? Try adding low dose GC as co-primary endpoint. Interim analysis of Phase 2 RCT: SRI-4 + sustained GC dose to ≤5mg/d or ≤BL from Wk16 to 28 was met more in Ianalumab (BAFF-R-i) vs PBO (44% vs 9%) @RheumNow https://t.co/JEnMWKilR6
Eric Dein
2 years 11 months ago
TM85 #ACR23 @RheumNow
IPF s/p lung transplant p/w diffuse bone pain
Exam: no synovitis, +crackles. Labs: ALP 203
CT chest: stable mycetoma
Xray: periosteal reaction
Dx: vericonazole periosititis
Positive Mucorales PCR, fluoride level 19 (ref <4)
Bone pain improved stopping voric https://t.co/Gt8mOAssvh
Aurelie Najm
2 years 11 months ago
Anti-fibrotics in RA-ILD
Retro analysis of 74 pts
AEs frequent 55% and discontinuation in 46% (more than in initial RCTs)
No diff between AF
FCV trajectory mildly improved
ABST2479 @RheumNow @Juge_P_A @PhilippeDieude #ACR23 https://t.co/GqsHxkIFgD
Meral K. El Ramahi, MD MeralElRamahiMD
2 years 11 months ago
Rashes in Rheumatology at #ACR23
Which disease entity are these palms pathognomonic for?
@RheumNow https://t.co/NmT1LTzWmm
Meral K. El Ramahi, MD MeralElRamahiMD
2 years 11 months ago
Therapeutic Ladder for Discoid Lupus:
1. Strict🌞protection, smoking avoidance
2. Antimalarials
3. Topicals/intralesional corticosteroids, topical CNI
4. Oral steroids, retinoids, MTX, MMF
5. Thalidomide, lenalidomide
6. IVIG, JAKi, Belimumab... BUT also Anifrolumab!… https://t.co/xSw0s12Uvk https://t.co/stIJ944d9A
Md Yuzaiful Md Yusof
2 years 11 months ago
#ACR23 Abstr# 2485 Belimumab therapy in RCT was associated with increased risk of psychiatric events inc suicidality vs PBO. When compared with standard immunosuppressant, real-world data using emulated trial design showed no increased risk @RheumNow https://t.co/Vqhc5yRsSA
Dr. Antoni Chan
2 years 11 months ago
A new innovative way of teaching MS ultrasound to students using teledidactic teaching with portable ultrasound devices resulted in a significant increase in knowledge comparable to the conventional course, Schäfer SV, Abst#2079 #ACR23 @RheumNow https://t.co/re0gErx5ke https://t.co/yPbS9Rj0az
David Liew drdavidliew
2 years 11 months ago
Late breaking at #ACR23:
extension of this study for dazodalibep (anti-CD40L) for Sjogren’s symptoms
Another six months with a crossover - & sustained symptomatic benefit after cessation. Fascinating, addresses a desperate clinical need, bring on the phase 3!
ABSTL10 @RheumNow https://t.co/zUfnGEZefj https://t.co/S3lLwhwl85
sheila
2 years 11 months ago
Complements & HCQ? (Prof Petri et al)
Significant ⬆️ in C3 (p=0.022) & C4 (p=0.003) levels with HCQ whole blood levels >50 ng/mL
Increasing blood levels of HCQ significantly assocd w/⬆️prob of achieving normal C4
Improving C3,C4; addtl benefit of HCQ?
#ACR23 ABST2327 @RheumNow https://t.co/5ucpXq9ngb

