sheila
2 years 9 months ago
Year in review: Long-term outcome of pts in the MAINRITSAN trials
Better outcome in pts who received RTX every 6 months for 18 months.
Implications? May consider shorter duration of maintenance tx (<36mos)?
#ACR23 @RheumNow #vasculitis https://t.co/18cXBlfxSG
Dr. Rachel Tate
2 years 9 months ago
Great Dr. Seo presents a great quote from Prof Seza Ozen during #ACR23 YiR "What you think of as a rare manifestation of a common disease is probably a common presentation of a disease you are not aware of (yet.)" A call to arms to continue to be curious! @RheumNow https://t.co/zVcIpHZznt
Mike Putman EBRheum
2 years 9 months ago
RTX-induction subgroup, ADVOCATE
Encouraging results (remission 71% vs 56% plbo wk 52), but never forget RTX was NOT redosed at month 6, so pts randomized to prednisone had NO TREATMENT from wk 20 - wk 52
Take results w/grain of salt
@RheumNow #ACR23 #ACRBest @anisha_dua https://t.co/zVhRX3IbiL
Mike Putman EBRheum
2 years 9 months ago
Regarding monitoring of ILD: "TLC takes a lot of time and is not necessary for follow up PFTs" @sclerodermaUM
Very nice pearl; I have been including TLC in subsequent PFTs, probably not necessary
Will change my practice immediately & save patients time
@RheumNow #ACR23
The window of opportunity concept in RA shifted our focus to trying to treat disease earlier and more aggressively to improve long term outcomes. A natural development of this was to reconsider the possibility of therapeutic interventions aimed at the prevention of rheumatoid arthritis.
Of the many exciting advancements for patients with psoriatic arthritis at ACR Convergence, one upcoming therapy stood out: the dual IL-17A/F inhibitor bimekizumab. Nearly two dozen bimekizumab abstracts will be featured at this year’s meeting and it recently received authorization in Europe and the U.S. for psoriasis. That makes this the year I plan to figure out where this drug will be useful for my patients with PsA.
TheDaoIndex KDAO2011
2 years 9 months ago
The gut matters and take care of your dental health! #Yearinreview Microbiomes and RA:
1. Changing gut micro biome in mice immediately triggers inflammatory arthritis
2. Mucosal breaks allow bacteria in and trigger citrullination. #ACR23 @RheumNow https://t.co/Iini9yE8dJ
Md Yuzaiful Md Yusof
2 years 9 months ago
#ACR23 Year in Review. Dr Seo did a great job in highlighting key papers.
#SLE #Tyk2 Phase 2 RCT of Deucravacitinib recruited pts of diverse ancestry. More pts on DEUC met SRI-4 response vs PBO. Question remains about the inverse/flat dose response. Going to Phase 3 @RheumNow https://t.co/68rYjEnWyN
Aurelie Najm
2 years 9 months ago
More studies emphasizing the role of microbiome in RA
1- Directly arthritogenic microbe strain confirmed in mice model
2- Gingivitis and oral microbiome can trigger citrullination and ACPA production
Dr Tomas Mustelin #yearinreview
@RheumNow #ACR23 https://t.co/uBd1UEgLRz
sheila
2 years 9 months ago
Vitamin D and bone health 🦴
Dr. Connie Weaver discusses the effect of Vit D on bone as well as dietary recomms fr diff groups.
Are your pts at risk of Vit d deficiency?👇
#ACR23 @RheumNow @rheumarhyme https://t.co/XcopyBHAoj
Meral K. El Ramahi, MD MeralElRamahiMD
2 years 9 months ago
Delighted to be joining my colleagues below to reporting on #ACR23 for @Rheumnow.
Tune-in for coverage and follow my colleagues below as well! https://t.co/rdLZbPGj3O https://t.co/hhwYf4YyLv
In clinical practice, pulmonary manifestations of rheumatic medical diseases such as rheumatoid arthritis (RA), psoriatic arthritis (PsA), and peripheral spondyloarthritis (pSpA) are typically not screened for upon diagnosis of a rheumatic disease in patients without any signs or symptoms suggestive of pulmonary involvement.
For over 70 years, glucocorticoids, (GC) have been a part of standard therapy in SLE. They are classically used to not only induce remission or treat an acute flare, but also as maintenance therapy. They are a valuable 'friend' if used wisely, and can become a 'foe' if used excessively.
Dr. Rachel Tate
2 years 9 months ago
Where does CAR-T fit in the future landscape? Dr. Seo reviews two case studies that question additional questions regarding efficacy, longevity of efficacy, and additional questions necessary to answer for our patients. #ACR23 @RheumNow https://t.co/mi4Z1tuJIV
TheDaoIndex KDAO2011
2 years 9 months ago
Half a pizza > once a week might help RA! Type of pizza matters as it is the ingredients- fresh mozzarella, olive oil are main ingredients #NotDominoes #YearinReview @RheumNow #acr23 https://t.co/i86JtUhXwW

