Dr. John Cush RheumNow
2 years 10 months ago
JAKi Safety & Efficacy in bDMARD-IR Patients with RA: Results Through 5 Years
This poster shows 5-year outcomes from the SELECT-BEYOND study in bDMARD-IR patients with RA, including TNFi-IR subgroup outcomes. Sponsored by AbbVie US Medical Affairs https://t.co/BRsCMnOnFT . https://t.co/lxfPs12mHb
NEJM reported today that polymyalgia rheumatica (PMR) patients who fail to respond to standard doses of prednisone therapy, were significantly better when given the IL-6 inhibitor sarilumab (than placebo).
The study was undertaken as there is a subset of patients who have relapsing PMR and because there are several studies suggesting the efficacy and safety of interleukin-6 blockade in PMR and giant cell arteritis.
Dr. John Cush RheumNow
2 years 11 months ago
Best quote from last nights Tues Night Rheumatology on #PMR , comes from Dr. Stephen Paget (#HSS) who said, "steroids to a new PMR patient are like spinach to Popeye" https://t.co/r7L1cUTJeT
Annals of Internal Medicine reports that the use of 18F-fluorodeoxyglucose (FDG) PET imaging at the time of a giant cell arteritis (GCA) diagnosis may help estimate the risk for aortic aneurysm formation.
Dr. John Cush RheumNow
2 years 11 months ago
X-sectional case-cntrl study w/ UK Biobank looked @ comorbidity w #PMR (n=1036) & GCA (102) pts (98% W; age 63 yrs) - pts rated their health as poor. Comorbid Dx included-more hypothyroidism (OR 1.34), HRT use (1.26), HTN (1.21-1.86) & cataract (1.51-3.84) https://t.co/GxpzN5NWug https://t.co/8J0IRMLK5g
Dr. John Cush RheumNow
2 years 11 months ago
New download on #PMR available now!
https://t.co/C4fCUQ5j8e https://t.co/3Fm5xG8EM7
Dr. John Cush RheumNow
2 years 11 months ago
Steroid Tapering in #PMR: What's the Gold Standard?
Dr. Anisha Dua, Chicago, discusses the gold standard tapering of glucocorticoids in polymyalgia rheumatica.
https://t.co/WyojhJQkN2 https://t.co/NarFqwNxEj
Dr. John Cush RheumNow
2 years 11 months ago
Retrospective EHR study of 7,970 gout pts from Singapore finds ~28% are poorly controlled, with only 46% prescribed allopurinol (13% @doses ≥300). Poor control assoc w/ male gender (adj OR 1.66), Malay ethnicity (aOR 1.27), CHF (aOR, 1.64) https://t.co/M8dJFIbZEV https://t.co/aUnLgUmvXN
Panelists Dr. Claire Owen, Stephen Paget, Anisha Dua and Jack Cush discuss diagnosis and monitoring in PMR during this week's Tuesday Night Rheumatology.
Dr. John Cush RheumNow
2 years 11 months ago
Cardiovascular manifestations of monogenic periodic fever syndromes - includes:
- Pericarditis (most common)
- Cardiac Amyloidosis
- Myocarditis
- CV complications of inflammation and steroid
- Premature atherosclerosis
https://t.co/iLfbPq2nzn https://t.co/T7Vtx5q8Y1
Dr. John Cush RheumNow
2 years 11 months ago
October is #PMR Month
PMR has come a long way from being an occasional referral and often test question, to now being a hot area of drug development and investigation
https://t.co/voVlxuRGZA https://t.co/NwEvws8cD3
Dr. John Cush RheumNow
2 years 11 months ago
Diagnosis and Monitoring of PMR https://t.co/D3ml0ZZCpb
Claire Owen
2 years 11 months ago
Excited to join @RheumNow for Tuesday Night Rheumatology and contribute to Make Rheum for #PMR this October🤩 https://t.co/8HqAVPDLXS
