Dr. John Cush RheumNow
3 years 7 months ago
#RNL2023: Kevin Deane: Anti-CCP positive leads to a 20-30% risk for articular clinical RA within 3-5 years
@RheumNow https://t.co/vPflDm22b2 https://t.co/7Al9I3Eidu
Dr. John Cush RheumNow
3 years 7 months ago
Retrospective study of Apremilast survival in 281 #psoriasis pts(22% w/ PsA) showed 1 yr drug survival=54%, less at 2 yrs (41%), 3 yrs (32%), and 4 yrs (30%). Half 1+ adverse events; D/C mostly for lack of efficacy (27%), adverse events (12%) https://t.co/2dm6H6cYNX https://t.co/F2YtzzWMdT
IgA nephropathy (IgAN) is a kidney disorder characterized by the buildup of immunoglobin A (IgA) in the glomeruli, which are bundles of capillaries that filter blood in the kidney. In advanced stages of the disease, the buildup of IgA in the glomeruli disrupts kidney functioning and, in approximately 30% to 40% of cases, leads to kidney failure.
Tofacitinib (Xeljanz) in patients with rheumatoid arthritis (RA) stood out among several other biologic and targeted synthetic disease-modifying antirheumatic drugs (sDMARDs) when it came to the incidence of interstitial lung disease (ILD), a retrospective cohort study showed.
Dr. John Cush RheumNow
3 years 7 months ago
Phase 3 trial of IV 200 mg qd hydrocortisone in 800 pts admitted to ICU for severe community-acquired pneumonia. Day 28 strongly favored IV Hydrocort vs PBO for mortality (6% v 12%; P=0.006), Mech ventilation (18% vs 29.5%), vasopressors (15% v 25%) https://t.co/TqxorRAuvc https://t.co/0R7kNaKgj5
Dr. John Cush RheumNow
3 years 7 months ago
#RNL2023:Kevin Deane: Anti-CCP positive leads to a 20-30% risk for articular clinical RA within 3-5 years https://t.co/MZJfg2lM70 https://t.co/eOkcwd4xMz
Dr. John Cush RheumNow
3 years 7 months ago
The Biosimilar "Buy In"
Dr. Rachel Tate, @uptotate , shared insights into these key discussions during RheumNow Live.
https://t.co/dD3uZCNQEo https://t.co/MuN91Oqbvo
Dr. John Cush RheumNow
3 years 7 months ago
Metformin Reduces Osteoarthritis Risk
Metformin may help cut the risk of osteoarthritis (OA) in those with type 2 diabetes, researchers reported.
https://t.co/dmyKssbWjO https://t.co/p7lPdjYfbU
Dr. John Cush RheumNow
3 years 7 months ago
Spondyloarthritis Innovations
The second day of RheumNow Live 2023 ended with a focus on axial spondyloarthritis, especially on the evaluation of the definition of the disease, the inheritance of it, and of course the treatment of it.
https://t.co/3JeNeE0EO6 https://t.co/fA1B2TA2xF
AAV is a multi-organ disease, which can be complex and may vary from person to person. Types of AAV include granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), and eosinophilic granulomatosis with polyangiitis (EGPA). This variety can make management challenging.
Dr. John Cush RheumNow
3 years 7 months ago
Have a Rheumatology question or case for Jack Cush? Record it here and we may feature it on an upcoming podcast. Tell us your name and where you practice rheumatology.
https://t.co/MMHvtkbz9l https://t.co/3aNijNJWkW
After an action packed weekend, RheumNow Live 2023 concluded on Sunday with a half-day session on systemic lupus erythematous and ankylosing spondylitis discussing many new medications that are revolutionizing rheumatology. Dr. Laurent Arnaud, a professor at Strasbourg University in France, however, took the time to review one of our oldest therapies: hydroxychloroquine.
Metformin may help cut the risk of osteoarthritis (OA) in those with type 2 diabetes, researchers reported.
Dr. John Cush RheumNow
3 years 7 months ago
FDA Approves Citrate-Free Formulation of Hyrimoz, a Biosimilar to Humira - but adalimumab-adaz HCF wont be available in USA until July 1, 2023 https://t.co/RRjxPW5I4O https://t.co/hf6NlkGG7W
Dr. John Cush RheumNow
3 years 7 months ago
Polypharmacy Increased in Psoriatic Arthritis
Psoriatic arthritis (PsA) is plagued by obesity, depression and increased comorbidities; now it appears that polypharmacy adds to the burden of managing PsA.
https://t.co/vispc9ei51 https://t.co/s45Nmpf46P
