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Humira biosimilars became available in EU 10/18; and will soon be available in the USA w/ Amjevita (Amgen) available Jan

Dr. John Cush RheumNow

3 years 8 months ago
Humira biosimilars became available in EU 10/18; and will soon be available in the USA w/ Amjevita (Amgen) available Jan 2023 & 6 others (Pfizer, BI, Samsung, Coherus, Sandoz, Biocon) after July 2023. https://t.co/m8cdJgM7UC
Retrospective Claims analysis 1663 #SLE pts shows pts w/ lupus nephritis (LN, 2916) had higher Charlson Comorbidity scor

Dr. John Cush RheumNow

3 years 8 months ago
Retrospective Claims analysis 1663 #SLE pts shows pts w/ lupus nephritis (LN, 2916) had higher Charlson Comorbidity scores ≥4 (72 vs 14%) & inpatient (41 vs 17%). LUPUS FLARES were more (61 vs 54%), more severe (11 vs 5%) & twice the cost https://t.co/tXI7SSalaV https://t.co/z0SorOQilb
Medical (AKA surgical) masks are not inferior to N95 fitted masks. A study of 1009 medical workers in 4 countries carin

Dr. John Cush RheumNow

3 years 8 months ago
Medical (AKA surgical) masks are not inferior to N95 fitted masks. A study of 1009 medical workers in 4 countries caring for COVID+ infected patients shows equal rate of PCR+ COVID tests (10.5% vs 9.3% +) (HR 1.14 [95% CI, 0.77 to 1.69]) https://t.co/wTuLHcOxlO https://t.co/gjqfLOU7JW
2002-2019 Canadian study of Rheumatology care: access has improved but problems exist, esp w/ DMARD use. In 112,494 new

Dr. John Cush RheumNow

3 years 8 months ago
2002-2019 Canadian study of Rheumatology care: access has improved but problems exist, esp w/ DMARD use. In 112,494 new RA pts, 84% saw Rheum <1yrs w/ 43% increase by 2019. Suboptimal DMARD use in elderly improved 55 to 69% https://t.co/tpv514P0GP https://t.co/AIRuf7u60d
Do not take antacids or PPI with mycophenolate. Magnesium &amp; aluminium hydroxide antacids (Maalox) will lower MMF Cma

Dr. John Cush RheumNow

3 years 8 months ago
Do not take antacids or PPI with mycophenolate. Magnesium & aluminium hydroxide antacids (Maalox) will lower MMF Cmax 33% & AUC 17% if given simultaneously. PPI also lowers AUC by ~33% https://t.co/D0eQWcON2J https://t.co/rK77lCmbVv https://t.co/5X0e6DBxAh https://t.co/ZpJtc8SdcG
One-third of patients admitted with giant cell arteritis (GCA) were rehospitalized within 6 months, largely because of complications potentially related to corticosteroid therapy, researchers found in a retrospective cohort study. Among the cohort of 1,206 patients hospitalized with GCA in the U.S., 6-month readmission rates stood at 34%, according to Radjiv Goulabchand, MD, of CHU Nîmes in France, and colleagues.
COMPLETE-PsA Trial studied MTX vs MTX + leflunomide in 78 active untreated PsA pts. MTX+LEF was superior to MTX alone at

Dr. John Cush RheumNow

3 years 8 months ago
COMPLETE-PsA Trial studied MTX vs MTX + leflunomide in 78 active untreated PsA pts. MTX+LEF was superior to MTX alone at wk 16 (PASDAS 3·1 vs 3·7; p=0·025). Combo group had more N/V (44% v 28%), ^ALT (31% vs 18%). https://t.co/22DhyJUeuo
RT @jrheum: Welcome, January 2023 ❄️.

It's the 50th year of the publication @jrheum ✨🎊!

View the full issue

The Journal of Rheumatology jrheum

3 years 8 months ago
Welcome, January 2023 ❄️. It's the 50th year of the publication @jrheum ✨🎊! View the full issue online 👉 https://t.co/GsZdjMZF1T #rheumatoidarthritis #spondyloarthritis #psoriaticarthritis #lupus #vasculitis #pediatric #gout #rheumatology #50thyearofpublication #jrheum50 https://t.co/keUVRVD8vW
COMPLETE-PsA Trial studied MTX vs MTX + leflunomide in 78 active untreated PsA pts. MTX+LEF was superior to MTX alone at

Dr. John Cush RheumNow

3 years 8 months ago
COMPLETE-PsA Trial studied MTX vs MTX + leflunomide in 78 active untreated PsA pts. MTX+LEF was superior to MTX alone at wk 16 (PASDAS 3·1 vs 3·7; p=0·025). Combo group had more N/V (44% v 28%), ^ALT (31% vs 18%). https://t.co/D2GYjbR7y2 #BestOf2022
INBUILD Study of 170 pts with autoimmune related ILD showed nintedanib signifi. slowed the rate of FVC decline in FVC de

Dr. John Cush RheumNow

3 years 8 months ago
INBUILD Study of 170 pts with autoimmune related ILD showed nintedanib signifi. slowed the rate of FVC decline in FVC decline over 52 wks (NIN -75.9 mL/yr vs PBO -178.6 mL/yr). AE's (mostly diarrhea) leading to D/C was NIN 17.1% vs PBO 10.2% https://t.co/CmbF5NQMfJ #BestOf2022
608 EARLY RA pts in BARFOT study had Xrays over time. 24% did not show Erosions after 8 yrs. Pt w/ NO Erosions were youn

Dr. John Cush RheumNow

3 years 8 months ago
608 EARLY RA pts in BARFOT study had Xrays over time. 24% did not show Erosions after 8 yrs. Pt w/ NO Erosions were younger, younger, w Less ACR criteria, & seronegative at Dx. They had more TJC, less SJC, lower ESR, less DMARDs & pred Rx. https://t.co/5jYNd7bwE3 https://t.co/z3Y0TPJTwd
The American College of Physicians (ACP) has issued an update of its guideline with clinical recommendations for treatments of primary osteoporosis and low bone mass in adults. In the new guideline, ACP recommends bisphosphonates as initial pharmacologic treatment to reduce the risk of fractures in males and postmenopausal females diagnosed with primary osteoporosis.
RHEUMATOLOGISTS: have you ever ordered a Fibroscan in patients taking Methotrexate?

Dr. John Cush RheumNow

3 years 8 months ago
RHEUMATOLOGISTS: have you ever ordered a Fibroscan in patients taking Methotrexate?
RT @EBRheum: Nifty little read about dx and tx algorithms in monogenic autoinflammatory disease

I think we need to star

Mike Putman EBRheum

3 years 8 months ago
Nifty little read about dx and tx algorithms in monogenic autoinflammatory disease I think we need to start generating more diagnostic algorithms and "approach to" articles Working on a series for my fellows and have had a hard time finding material! https://t.co/DYmgSyjILi
There is considerable overlap between fibromyalgia tender points and an enthesitis score in axial spondyloarthritis pts.

Dr. John Cush RheumNow

3 years 8 months ago
There is considerable overlap between fibromyalgia tender points and an enthesitis score in axial spondyloarthritis pts. 526 pts in the Predict-SpA study (53% men, 38% FM) assessed 18 TP and 13 Entheses found ICC between both scores of 0.7 https://t.co/ESmP26plDB https://t.co/7X1XhyML0f
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