Imaging And Remission Axial Spondyloarthritis - Dr. Olga Petryna Save
Dr. Olga Petryna from EULAR2020 Virtual Conference
OP0079 - what MRI findings are mos
OP0314 - Drug free remission in AxSpA
Transcription
Hello, this is Olga Petrina presenting you with updates from virtual EULAR twenty twenty. Today I would like to talk about imaging in axial spondyloarthritis. Posterior OP0079 is a brief one but interesting in my opinion. It presents us with ASAS MRI group updates on radiographic lesion definition in MRI of patients with sacroiliitis in axial spondyloarthritis. So the purpose of this update was to reach consensus on what lesions are considered the most pertinent ones that have the highest predictive value of subsequent diagnosis of axial spondyloarthritis and the lesions that made a cutoff of ninety five percent specificity were the following ones: Erosions in two or more consecutive slices had sensitivity of eighty three percent as well as erosion in three or more sacroiliac joint quadrants had sensitivity of 90%.
Also fat lesion with a depth of one centimeter or more in one or more sacroiliac joint quadrants were considered a high priority candidates that have best predictive value of subsequent diagnosis of axial spondyloarthritis. Second abstract is also interesting in my opinion OP0314 is the study observational study from Desert cohort evaluating factors associated with the five year drug free remission in early onset axial spondyloarthritis. In this study it was found that only seventeen percent of the patients were able to achieve drug free remission at year five and out of them fifty percent were male patients with disease duration of one point two years. Twenty six percent of those patients had MRI findings of sacroiliitis and seventy one percent of them had positive HLA B27. It was found that patients who were able to achieve five year drug free remission were less likely to have peripheral joint involvement.
They usually had lower disease duration as well as lower disease activity score by PASDAI and ASSA CRP. It was also found that patients were less likely to use NSAIDs and the conventional DMARC had no impact on achievement of drug free remission. Interestingly enough, was found that findings of bone marrow edema had no impact on achievement of remission, although patients who were able to achieve this target tended to have lower Berlin scores on spine MRI. I find overall this fine study is interesting, give us some idea about who could be a good candidates for remission in early Axial Spondyloarthritis and of course more studies would be needed to assess how feasible this assessment is and how feasible it is for patients to stay off medications long term. Thank you for listening.
If you would like to learn more, please follow us on RheumNow. Thank you. Goodbye.
Also fat lesion with a depth of one centimeter or more in one or more sacroiliac joint quadrants were considered a high priority candidates that have best predictive value of subsequent diagnosis of axial spondyloarthritis. Second abstract is also interesting in my opinion OP0314 is the study observational study from Desert cohort evaluating factors associated with the five year drug free remission in early onset axial spondyloarthritis. In this study it was found that only seventeen percent of the patients were able to achieve drug free remission at year five and out of them fifty percent were male patients with disease duration of one point two years. Twenty six percent of those patients had MRI findings of sacroiliitis and seventy one percent of them had positive HLA B27. It was found that patients who were able to achieve five year drug free remission were less likely to have peripheral joint involvement.
They usually had lower disease duration as well as lower disease activity score by PASDAI and ASSA CRP. It was also found that patients were less likely to use NSAIDs and the conventional DMARC had no impact on achievement of drug free remission. Interestingly enough, was found that findings of bone marrow edema had no impact on achievement of remission, although patients who were able to achieve this target tended to have lower Berlin scores on spine MRI. I find overall this fine study is interesting, give us some idea about who could be a good candidates for remission in early Axial Spondyloarthritis and of course more studies would be needed to assess how feasible this assessment is and how feasible it is for patients to stay off medications long term. Thank you for listening.
If you would like to learn more, please follow us on RheumNow. Thank you. Goodbye.
If you are a health practitioner, you may Login/Register to comment.
Due to the nature of these comment forums, only health practitioners are allowed to comment at this time.