Systematic literature review of sleep Rx in Fibromyalgia - 47 RCTs, 11094 pts, found cognitive behavioral Tx (CBT) significantly benefitted insomnia, but not pain. Pregabalin & sodium oxybate had small effect, but Amitriptyline, milnacipran, & duloxetine showed no benefit for… https://t.co/ReommvC5qO https://t.co/UnSM3HnWLV

J&J announced the FDA jas granted the investigational drug, nipocalimab (FcRn recpt Ab), with Fast Track designation for its study in adult patients with moderate-to-severe Sjögren’s disease https://t.co/TB2cESMLQi https://t.co/IC7PQP2fcx

Ontario study of 11 641 older psoriasis pts & hospitalized serious infx in those on b/tsDMARDs. IL-12, IL-23, and IL-17 inhibitors were assoc w/ 35% lower rates of SIE, while MTX, other older systemic meds, TNFi were not incr/decr. But JAK inhibitors had signif 3 fold incr in… https://t.co/ffFdHjme65 https://t.co/DkTsadUNx2

Study of 26 Enthesitis-related arthritis (ERA) pts (mean Dx age 12 yrs; 77% male; 58% B27+). These were later assessed as adults (20yrs age, <35yrs). Most were in remission/LDAS, but ~20% had synovitis or enthesitis, 73% SI Dz, 15% hip & 8% spinal damage https://t.co/FFEhyA5I6A https://t.co/hE65GNcFpY

RF levels may offer critical insights when treating RA. Learn why from two renowned rheumatologists. Sponsored by UCB https://t.co/yuUhmZR5bC https://t.co/Fsbu8Vztna

Channeling Bias and Cancer Risk with Biologic or Targeted Synthetic DMARDs A retrospective US administrative claims cohort study of Rheumatoid arthritis (RA) patients on tumor necrosis factor inhibitors (TNFis), non-TNFi biologics, or Janus kinase inhibitors (JAKis) found a… https://t.co/8jqJwkEbZF https://t.co/cQ9aheU5mc

Indigenous peoples of the Pacific, particularly those of Polynesian descent, have a high prevalence of hyperuricaemia and gout. Gout in Indigenous peoples of the Pacific is severe, associated with family history and is experienced at a relatively young age.… https://t.co/phf5RRkJzE https://t.co/q4VO34Ea5z

Earlier ACL reconstruction and a lower risk of knee osteoarthritis A preclinical study by HSS investigators found that earlier ACL reconstruction led to lower immune cell activity, less inflammation and fewer joint changes associated with knee osteoarthritis compared to delayed… https://t.co/DnY5nGLah4 https://t.co/ogLTF88CVL

Glucocorticoid Toxicity Index Dr. John Stone has led the effort to develop the GTI - glucocorticoid toxicity index. In this review article he acknowledges the need and benefit of steroids, but details a novel means to identify and limit the untoward effects of glucorticoids… https://t.co/xR8D4Jpjfv https://t.co/LyfHrbneTO

Comprehensive review of the management of knee osteoarthritis - topicals, analgesics, narcotics, intraarticular, metabolic, nutraceuticals, TENS, acupuncture and biologics. https://t.co/SEyG4IQ0bh https://t.co/f6UY4hEl18

Single Center study of 112 RA pts from Morocco used machine learning (ML) logistic regression model & identified #Depression in 48% (HADS score >8) w/ 76.5% accuracy, 72.2% precision, 81.2% recall, and an area under the receiver operating characteristic curve (ROC AUC) of… https://t.co/LBvdVEzDGJ https://t.co/bYLqsFagbR

2024 Rheumatology Year in Review 2024 was a year of surprising new growth in technology, with the expansion of new therapeutic options for many patients and clinicians. https://t.co/XuEG8Hrc9e https://t.co/ja5OoZXdWo