Cardiology is on! Dr. Olin discusses Fibromuscular Dysplasia findings on imaging Definite: string of beads and/or focal narrowing in right setting / location Possible but nonspecific: dissection, ecstasia, aneurysm, and tortuously @RheumNow #ACR24 https://t.co/Dr81KQfLSf

Why is there female predominance in #SLE - the extra X chromosome in females (XX) may not be inactivated properly- usually maintained by the long non-coding RNA #Xist #ACR24 abst#2599 @RheumNow https://t.co/C9Qj5zSnpN

Updated ACR guidelines on management of lupus nephritis (LN). Consider early biopsy. Focus on triple therapy in LN. From the panel discussion, Tacrolimus can be an alternative to CNI (Voclosporin) where there is no access to this. Manage comorbidities such as CV risk, bone… https://t.co/4R02YnRXDP https://t.co/3J7YcF5ucQ

Galloway et al. 117,050 individuals. VTE risk in RA consistently increased, irrespective of age, sex, BMI. Risk VTE 46% higher in RA! @RheumNow #ACR24 Abstr#1901 https://t.co/SQPcPiBeF2 https://t.co/BQkERUsGlL

Do pts w autoimmune disease (AID) respond differently to immune checkpoint inhibitors (ICI) & have different mortality or iRAE risk vs pts without AID? Study of pts on ICI showed no significant difference in mortality in pts w & without pre-existing AID Ab2532 #ACR24 @RheumNow https://t.co/suywDdGIB1

Applying the guidelines to Cases- Dr M Dall’Era for a pt wit extrarenal lupus and active LN. #ACR24 @rheumnow https://t.co/lvOUWjEdEz

Non-pharm tx in TAK - not something we always think about but… Impressive effect of resistance exercise!! Not just in symptoms but also inflammatory markers Per Dr. Springer - even a stress ball could be enough for UE vascular health in these pt @RheumNow #ACR24 https://t.co/3O46gobbMX

The updated 2024 ACR Guideline for Dx and Tx of #lupus nephritis is here! Dr. Lisa Samaritano discusses the key recommendations 👇 For all pts: screen for LN, give HCQ and RAAS for pts with ⬆️ proteinuria GCs in pts w/ LN class III/IV &/or V. @Rheumnow #ACR24 @rheumarhyme https://t.co/wLVRGktR59

The overview for #lupus nephritis tx. Triple therapy is preferred as first line due to: 1. RCTs (BLISS-LN & AURORA 1) showing improved outcomes w/ triple txs 2. Nephron loss happens with ongoing LN - time is kidney! @RheumNow #ACR24 https://t.co/IQo3q3O1pt

Recommend "Triple Therapy" = Glucocorticoids + two other agents Practically, that means MMF + belimumumab OR CNI for most pts For the CYC afficionados, the lower-dose EUROLUPUS protocol is preferred #ACR24 @RheumNow https://t.co/0gRISXSw0c