A high ANA titer (≥1:640) in individuals without an autoimmune disease was found to be strongly associated with liver-related disorders, including nonalcoholic and alcoholic liver disease Arthritis Care & Research https://t.co/tkMpPFPnhc https://t.co/Bk9JXWTsOU

JAMA Pediatrics study of 1,473 young US adult, finds 1/4 use cannabis or alcohol for sleep (18% cannabis; 7% EtOH), even though these may interfere with quality or ability to stay asleep. In those using cannabis in the last yr, 41 reported using cannabis to sleep. https://t.co/fdW6bdDM3I

Arthritis Pain and Education Gaps Linked Save New research from The University of Texas at Arlington shows that differences in state welfare policies are linked to rising arthritis-related joint pain across much of the U.S. https://t.co/cGRH9X6pMZ https://t.co/J1SDeKrytn

Failure of IL-17 inhibition in Lupus nephritis. 31 LN pts enrolled in phase 2 DBRPCT of secukinumab 300 mg IV, but was terminated early for futility (complete renal response at week 52 was lower with secukinumab (24.2%) than with placebo (36.3%). https://t.co/471TolqtFk https://t.co/gKi2Z2MZHS

Muscle mass & JAKi? 15 active RA pts (+ sarcopenia risk) Rx w/ tofacitinib - signif. improved @1 mo. @6 mos muscle mass signif improved (+242 cm3, +4%, p=0·017) {less w/ NSAIDs); w/ signif creatinine incr (0.06 mg/dl) & decr in serum IL-6, IL-1 & TNF. No change in CK, myoglobin, https://t.co/taY7DisMOS

Why Brittle Bones Aren't Just a Woman's Problem Osteoporosis is more common in women, prompting routine screenings for them at age 65. As a result, men might overlook getting a scan, which may not be suggested by an orthopedic specialist. However, about 20% of men over 50 will https://t.co/ggyse5ZDPV

Pregnancy Management in Inflammatory Bowel Disease: A Global Consensus Consensus guidance on the management of pregnancy in patients with inflammatory bowel disease (IBD) was simultaneously published in six international journals, including The American Journal of https://t.co/F6er2mpUoV

BMJ Systematic review of 217 RCTs w/ 15 684 pts shows most beneficial exercises for Knee Osteoarthritis are aerobic activities such as walking, cycling, or swimming significantly mitigated pain during both short and mid-term follow-up periods https://t.co/WmQBFNis6t https://t.co/KXv2mogvZx

Osteonecrosis: suspect with trauma, high-dose steroids, alcoholism, renal failure, transplantation, SLE, thrombotic states (e.g., sickle cell anemia, hemoglobinopathies), radiation injury, pancreatitis, gout, pregnancy, hyperlipidemia, & caisson disease (decompression sickness) https://t.co/y6iYd5fWZ2

Review of IL-1 family cytokines in inflammation and immunity - including, IL-1, IL-18, IL-33, IL-36, IL-37, IL-38, IL-1Ra, etc. Full read -- Good Reference!! https://t.co/01o05qYPjU https://t.co/HLcfPM2cPw

Scientific American takes a look at the beneficial effects of: Omega-3 Fatty Acids Vitamin D Curcumin (basic overview for all) https://t.co/jv5FrGQQLJ https://t.co/vP26OPaTiS

A cohort study of 1 548 538 mother-child pairs with antenatal exposure to steroids (ACS) found a significantly increased risk of res v nonrespiratory infections in preterm & full-term children up to 21 years. (incidence rate, 65 vs 40 & 30 vs 18 per 1000 person-Yrs, https://t.co/Vh4TNYMXgo