Tweets
Using #MachineLearning for predicting flares in axSpA @DiegoBenavent et al, data from METEOR-SpA registry showed the ff predictors of flares thru the reduced logistic regression model:
🔅lower ASDAS
🔅enthesitis
🔅prior flares
🔅longer treatment duration
@RheumNow #ACR24 abs559 https://t.co/wyIo9gnKVJ
sheila @RHEUMarampa ( View Tweet )
1 year 2 months ago
📈 Data from @UIowa_Rheum on how rurality impacts delay to diagnosis in #GCA
📍 0747
👉🏼 People living in more rural areas have an increased time to diagnosis & treatment- further prospective studies needed to delineate effects of rurality further
@RheumNow #ACR24
@LemonReneeNi https://t.co/3YMcI9ha3T
Mrinalini Dey @DrMiniDey ( View Tweet )
1 year 2 months ago
Harkins @DrTrishHarkins et al. People with PMR exhibit an accelerated physical aging phenotype at baseline. High rates of frailty (41%), pre-frailty (28%), cognitive impairment (74%!), sarcopenia (23%), osteoporosis (21%) @RheumNow #ACR24 Abstr#0740 https://t.co/4ZT8VtGi1W https://t.co/xBQ5CLlb5A
Links:
Richard Conway @RichardPAConway ( View Tweet )
1 year 2 months ago
Does apremilast have cardiometabolic benefits?
Abstract 0598: In PsA patients, 1-year treatment with apremilast associated w/ ↓ body fat mass, including android fat, and was linked w/ improved disease activity (DAS28-CRP). #ACR24 @RheumNow https://t.co/11n4gQN7Xo
Akhil Sood MD @AkhilSoodMD ( View Tweet )
1 year 2 months ago
Characteristics of difficult-to-treat AS accdg to a retrospective study by @DaoudAnsaam @mmagrey1 et al
⬆️ BMI
+ comorbidities: HTN, CKD, depression
+ EAMs: IBD, Pso, iridocyclitis
+ HLA-B27
Interesting real world data.
@RheumNow #ACR24 abs573 https://t.co/GlE4tFpsSz
sheila @RHEUMarampa ( View Tweet )
1 year 2 months ago
FDA has given FDA Breakthrough Therapy designation to Nipocalimab for treatment of adults w/ moderate-to-severe Sjögren’s disease. NIPO is an Ab to neonatal Fc receptor (FcRn), & was tested and shown effective in Sjog in the Phase 2 DAHLIAS study - a plenary presentation at… https://t.co/aQDp7iPKXD https://t.co/hJ8fe6JwxC
Dr. John Cush @RheumNow ( View Tweet )
1 year 2 months ago
#0588
🔬 Sex Differences in PsA
➡️n=1405, pooled RCT data
♀️49%: Milder PsO (PASI 7.8 v 11.5), higher BMI, longer PsA duration,⬆️ fatigue/pain vs ♂️
♀️worse QoL/functional impairment
♂️More dactylitis (45% v 37%)
🩺 Sex-specific factors matter in PsA
#ACR24 @RheumNow
Caoilfhionn Connolly @CaoilfhionnMD ( View Tweet )
1 year 2 months ago
Puechal et al. Serial ANCA testing may predict relapse in a large group of AAV patients but is NOT useful for individual patients. @RheumNow #ACR24 Abstr#0721 https://t.co/ClvTk2Tlar https://t.co/k4vc7l9jzK
Links:
Richard Conway @RichardPAConway ( View Tweet )
1 year 2 months ago
#0589
🔬Time to Response in PsA Domains: Secukinumab
➡️Post-hoc analyses, n=1366
🔑Median time (wks) to MCID 👇
🔴Systemic inflammation <2
🔴MSK: ~4 wks (enthesitis~12)
🔴Fatigue~7–8
🔴PASI75~8–12; nails ~24
🩺 Rapid MSK & QoL benefits precede skin/nail
#ACR24 @RheumNow https://t.co/WfqkryA1CC
Caoilfhionn Connolly @CaoilfhionnMD ( View Tweet )
1 year 2 months ago
Data from the study by Dr. Aguilar et al showed that high dose NSAID use was not assoc'd with incident HTN in their cohort of early axSpA patients.
Shows important role of NSAIDs in #axSpA but still should be used judiciously
@RheumNow #ACR24 abs540
@rheum_cat @rheumarhyme https://t.co/LK5yFZynu4
sheila @RHEUMarampa ( View Tweet )
1 year 2 months ago
Switching vs cycling - which is better? In PsA & axSpA, a real-world analysis shows that switching to IL-17Ai after TNFi discontinuation may lead to similar or better outcomes compared to cycling to another TNFi. Data from the CorEvitas PsA/SpA Registry. Abstr#0585.… https://t.co/AJP4NBjmzr
Antoni Chan MD (Prof) @synovialjoints ( View Tweet )
1 year 2 months ago
De Lorenzis et al. MMF in LcSSc. Target Trial Emulation. 1435 patients. Incidence vasodilator treatment escalation over 41 months, 1/100py in MMF vs 7.3/100py in controls. @RheumNow #ACR24 Abstr#0688 https://t.co/D3qTUHyIIc https://t.co/6azvaS0ElL
Links:
Richard Conway @RichardPAConway ( View Tweet )
1 year 2 months ago


