Calif Cohort of 19340 rheumatic pts, finds Cardiovascular events (CVE) in 1.4% & antiphospholipid syndr in 5.5%. CVE increased risk of adverse pregnancy outcomes (>50%), including Sm for Gestational age (aRRs 1.2-1.5), Premature birth (aRR 1.6) https://t.co/9lxzrOVEks https://t.co/Jcm7tH61cv

Lit review of ILD in anti-synthetase syndrome finds no conclusive evidence of effective treatment. 10 studies, 514 pts (68% female); Hi Res CT positive in 87% w/ 49% having NSIP pattern. 48% Jo-1+, 28% Ro52+. Low improvements w/ RTX (12%), CYC (17%). https://t.co/oJ0EMAE7d0 https://t.co/bDiA1h9hO7

Systematic review: RX of macrophage activation syndr (MAS), included 57 reports, 1148 MAS pts (889 sJIA, 137 SLE). Most effective was high-dose GCs, IL-1 (83%) & IFNγ (93%) inhibitors, especially in sJIA-MAS. Also Ciclosporin, etoposide, Ruxolitinib https://t.co/4EnMOnlcYl https://t.co/PQnAZLvVwq

Full Read Overview of the safety of bDMARDs/tsDMARDS - contraindications, precautions, & boxed warnings for treatment of RA, PsA, SpA, JIA - safety checklist for a class of drugs you use and diseases you treat https://t.co/TIdCtJjF21 https://t.co/UE0nGbESDB

Study of 136 referred LBP pts (71 w/ DDD, 38 DISH, 27 axSpA) found significant overlap of imaging features in all 3. SpA-like spine CR features were found in 1/4 of patients with DISH, and MRI BM edema found in 1/3 of those patients. https://t.co/dKIcuE3IGZ https://t.co/OITtOKEuNC

Decline in Physician Trust During the COVID-19 Pandemic AMA reports that following the COVID-19 pandemic US adults trust in physicians and hospitals decreased, and was associated with lower odds of COVID vaccination. https://t.co/3XcMYcnzD3 https://t.co/yiIvOp1o5a

Frequency and Features of CPPD An international cohort study of patients with CPPD disease identifies both acute and chronic inflammatory phenotypes, each with distinctive clinical and imaging diagnostic features. https://t.co/3ox3YjVh5w https://t.co/1pB9f42a9M

Ischemic Forearm Exercise Testing is used to Dx McArdles disease & the absence of elevated blood lactate levels during exercise in pts w/ myophosphorylase deficiency (McArdle disease) https://t.co/pNxl6qnnIR https://t.co/kOyk45Necd

NEJM Case: A 29-year-old woman with SLE presented to the dermatology clinic with 2-weeks of itchy, painful rash on her nose and hands that came on with cold weather. What do you think? https://t.co/jm0Zzu1gfj https://t.co/sAgZipPmaC

Study of 201 pts w/ chronic pain, prevalence of anxiety was 19%; higher in women (OR 7.94) longer pain (OR:1.3) & severe pain(OR:18.7) https://t.co/LD6pjH25qv https://t.co/mrlEo0UkEw

2024 EULAR Points to consider when treating patients with cancer https://t.co/oXO8m8mrfJ https://t.co/v69zPteDr0

Pain Reduction with Methotrexate in Knee Osteoarthritis The Annals of Internal Medicine reports that oral, low dose, weekly methotrexate significantly reduced knee osteoarthritis (KOA) pain, stiffness, and function in a randomized controlled trial. https://t.co/ayMD1V67fH https://t.co/Es3oPYM8Y3