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174 Active RA pts not responding to MTX were started on TCZ. High GM-CSF (> 5 ng/ml and > 10 ng/ml) at baseline were the independent predictors of poor response to TCZ at Wk24. high GM-CSF had signif higher DAS28-ESR & cytokine levels at baseline https://t.co/AreLBseJDq https://t.co/OyIOkiUOT1
Dr. John Cush @RheumNow ( View Tweet )
1 year 6 months ago
268/279 SLE pts w/ kidney biopsy for proteinuria were Dx w/ lupus nephritis. Proliferative LN (III/IV+V) had higher levels of C1q, chromatin, dsDNA, ribosomal P Abs. C1q & dsDNA independently assoc w/ proliferative LN. AutoAbs decreased in proliferative LN https://t.co/oq3JhrFlz8 https://t.co/nxQBZvoOzP
Dr. John Cush @RheumNow ( View Tweet )
1 year 6 months ago
Full read overview of myositis associated - ILD (and treatments), including: - Case examples - Antisynthetase Syndrome - Anti-MDA5 Amyopathic DM - Interstitial Lung Disease in Myositis https://t.co/PhfuuBHOYf https://t.co/OC1GmWkYyO
Dr. John Cush @RheumNow ( View Tweet )
1 year 6 months ago
Problems With Laboratory Tests in the Management of RA https://t.co/kUYivP7SHW https://t.co/nFtB75N0jQ
Dr. John Cush @RheumNow ( View Tweet )
1 year 6 months ago
Enhance your clinical practice with insights from the EULAR 2024 Poster Hall Presentations, now on https://t.co/V10S4oVFsv. This year's conference showcases pivotal research in rheumatology. Visit https://t.co/gL38TVZRkM to stay at the forefront of medical innovation. https://t.co/cZontmAPTq
Dr. John Cush @RheumNow ( View Tweet )
1 year 6 months ago
ICYMI: Metrics Used by Rheumatologists in RA https://t.co/7Qr4cYvqp1 https://t.co/1FnyNpfhqi
Dr. John Cush @RheumNow ( View Tweet )
1 year 6 months ago
Pain in RA: Different Drugs for Different Mechanisms https://t.co/pOETFkTIkS https://t.co/Vn5zgrYsKR
Dr. John Cush @RheumNow ( View Tweet )
1 year 6 months ago
Top 20 Best Rheumatology Hospitals - 2024 Johns Hopkins Hospital in Baltimore has been named the top hospital for rheumatology by U.S. News & World Report. This is the 7th year in a row they have held this spot. https://t.co/ZHogsqVR5H https://t.co/45qm4Li4ii
Dr. John Cush @RheumNow ( View Tweet )
1 year 6 months ago
Study of 478 CA pts Rx w. anti-PD-(L)1 Ab or anti-CTLA4 Ab - 28 (6%) had pre-existing Autoimmune Dz (AI). irAE (w/ checkpoint inhib) were higher w/ preexisting AI (57% vs 35%), but activity of AI was not related to irAEs occurrence. https://t.co/CHIdaH91qR https://t.co/XuaLk4D205
Dr. John Cush @RheumNow ( View Tweet )
1 year 6 months ago
Prospective cohort study from 474 055 participants in UK Biobank, finds long-term exposure to air pollutants, NO2 etc, assoc w/ a 19% to 47% increased risk incident psoriasis. Air pollution and genetic predisposition also significantly incr incident PsO https://t.co/ogX81ybU3l https://t.co/Mvd6tAj2j6
Dr. John Cush @RheumNow ( View Tweet )
1 year 6 months ago
IL-17 inhibitor Brodalumab is not often talked about, but its approved for PsO & PsA. German study of 227 PsO w/ 37 PsA pts Rx w/ BRO - good, rapid response by 3 mos. 1 year drug survival rate was 76.2%, (mean discontinuation=8.3 mos. https://t.co/4byFoc96Zs https://t.co/sPomX0s8aa
Dr. John Cush @RheumNow ( View Tweet )
1 year 6 months ago
192 RA pts on MTX: GI Sxs studied w/ MISS (MTX intolerance severity score). GI intolerance seen in 56%, Nausea & pain post-MTX most common. More in afro-descendants, w/ FM, Steroids, or JAKi. MISS results unrelated to Route, Gi Dz, age, MTX dose https://t.co/EROmZQo1Zs https://t.co/SOMzzXXj0b
Dr. John Cush @RheumNow ( View Tweet )
1 year 6 months ago
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