Tweets
Maintenance of remission in GPA/MPA.
RTX for 48 months sounds good to me.
#EULAR2024 https://t.co/5YGwOHhCuX
Nouf Al hemmadi @NoufAhmedAlham2 ( View Tweet )
1 year 7 months ago
Potential efficacy of JAK inhibitors in VEXAS syndrome
#EULAR2024
NZ https://t.co/HziLUgo1gA
Annals of the Rheumatic Diseases @ARD_BMJ ( View Tweet )
1 year 7 months ago
500+ pts AxSPA
No difference in drug discontinuation between IL-17i, TNFi, IL23i over time
Adjusted for CRP, co-medication w/ MTX + classic covariates
IL-17i and IL-23i had experienced a higher number bDMARD failures
#EULAR2024 POS0259 @RheumNow https://t.co/F3B6uXyAca
Aurelie Najm @AurelieRheumo ( View Tweet )
1 year 7 months ago
Cohort from Netherlands 400+ PsA pts IR first bioDMARD
300+ switched TNFi->IL-17i, 99 cycled TNFi->TNFi
3year retention rates
12 mo 75% cyclers 80% swappers
24mo 60% cyclers 56% swappers
No difference in treatment failure or DAS28 CRP
#EULAR2024 @RheumNow POS0278 https://t.co/J8ONjVAFqG
Aurelie Najm @AurelieRheumo ( View Tweet )
1 year 7 months ago
What is the meaning of mechanical stress-induced sacroiliac BMO MRI after childbirth in healthy women?
5yrs follow up MRI study shows:
-decrease in BMO
-1/3 BMO @ 5-year follow-up
-15% ASAS definition of sacroiliitis
-No correlation w/ symptoms
@RheumNow #EULAR24 OP0222
Aurelie Najm @AurelieRheumo ( View Tweet )
1 year 7 months ago
Understudied neurological involvement 🧠in RA
in pts > 65 vs. matched HC
-larger lateral cerebral ventricles
-brain atrophy
-shrinkage of thalamus + frontal cortical regions
-association w/ clinical depression
@RheumNow POS0148 #EULAR2024 https://t.co/2mV4qGyBtW
Aurelie Najm @AurelieRheumo ( View Tweet )
1 year 7 months ago
BARI reduces nociplastic pain, small cohort RA n=13
-wk 12 ACR FM score 14 vs 10.5 p=0.03
-fMRI data: reduction connectivity between DMN and posterior insula & between IPL & anterior/middle insular regions
Directs mechanims yet to be investigated
@RheumNow POS0310 #EULAR2024 https://t.co/jGgvS5qqV6
Aurelie Najm @AurelieRheumo ( View Tweet )
1 year 7 months ago
Is RA always preceded by clinically suspect arthralgia? Cohort 650+ pts CSA = 83 pts no CSA = 616 pts
Pts w/ no CSA: -older -more frequent acute onset of symptoms -higher SJC -increased CRP -less ACPA+ No sure how accounted for memory bias
#EULAR2024 @RheumNow POS1030 https://t.co/dJeN41ax5P
Aurelie Najm @AurelieRheumo ( View Tweet )
1 year 7 months ago
9 new MOAs in SLE to review - anti-cd38, cd40, ubiquitin ligase, tyk2, toll 7/8, baff-r, blyss/april, CAR-T, glycosylated cd20 @rheumnow #EULAR2024
Peter Nash @drpnash ( View Tweet )
1 year 7 months ago
EFFICACY AND SAFETY OUTCOMES OF TAK-279, A SELECTIVE ORAL TYROSINE KINASE 2 (TYK2) INHIBITOR, FROM A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED PHASE 2B TRIAL IN PATIENTS WITH ACTIVE PSORIATIC ARTHRITIS - smells tastes & looks like a Tyk2 - acne signal? @rheumnow #EULAR2024
Peter Nash @drpnash ( View Tweet )
1 year 7 months ago
EFFECTIVENESS & COST-EFFECTIVENESS OF PATIENT-INITIATED FOLLOW-UP SUPPORTED BY ASYNCHRONOUS TELEMONITORING IN SPA (TeleSpA-STUDY): PRAGMATIC MULTICENTRE RVT cost effective but no one will ever be examined again especially for pathology outside joints! @rheumnow #EULAR2024
Peter Nash @drpnash ( View Tweet )
1 year 7 months ago
FAPI PET/CT entheseal & synovial fibroblast activation predicts PsA in high risk PsO better than MUS @RheumNow #EULAR2024 https://t.co/uqmEvMg9WN
Peter Nash @drpnash ( View Tweet )
1 year 7 months ago
