Flavinoids (herbs, cherries, berries) have clinical efficacy in #Gout. Review of the mechanisms of flavonoids in gout includes: - Cox-2 inhibition - Lowers xanthine oxidase activity (mediated thru inflammasome, NOD/TLR4, NFKB, OAT1 & OAT3 transporters https://t.co/UC55GGZBCJ https://t.co/L6nE3BMIj1

Molecular Profile for Cardiovascular Risk in Rheumatoid Arthritis A new study led has managed to establish, for the first time, the molecular profile of those patients with rheumatoid arthritis who have a higher risk of suffering cardiovascular events. https://t.co/VVKR2G91VQ https://t.co/ZZNLJpoyNA

Cannabis Use is Common, But is it Safe? Two current JAMA reports suggest that cannabis use is not only common, but that if heavily used may increase mortality rates. https://t.co/ue9IRcbkCm https://t.co/IiG1RsIJiS

Is there an Increasing Risk for Tick-Borne Disease ? JAMA article purports this to be so..... I think not - not unless you live in endemic areas. Other wise these still are rare, rare or misdiagnosis based on serologic inaccuracies - just my opinion.https://t.co/zkMPYPCW3r https://t.co/ZfnWgV6aMY

2023 EULAR classification criteria for hand osteoarthritis A EULAR consensus group has established classification criteria for overall hand osteoarthritis (OA) and its subtypes (interphalangeal OA and thumb base OA). https://t.co/wIgjYB2rXF https://t.co/TjSILyC4IT https://t.co/3x6YtXW81u

Israeli study shows the prevalence of Psoriatic arthritis has tripled since 2006 - 2006: 0.073% - 2016: 0.165% - 2022: 0.221% ~2 fold higher rate if Jewish, High SES, Obese https://t.co/RMWcIZvfjb https://t.co/9H6sauSEZK https://t.co/Fhj64pADdJ

Ankylosing spondylitis Tx w/ Tofa- How quick do they respond? Post hoc analysis 269 pts: - 4 wks for Pain >30% - 4 wks for ASDAS improved ≥ 1.1 points - 8-24 wks for ≥ 50% improved pain, enthesitis, AM stiffness, BASDAI & fatigue https://t.co/YOZgRLfPNc https://t.co/egkG76gz2E https://t.co/ZknXhKE0N4

FDA has approved upadacitinib (Rinvoq), for use in pediatric patients (age >2 years) w/ active polyarticular juvenile idiopathic arthritis (pJIA) & psoriatic arthritis (PsA), after inadequate resp/intolerance to TNFi. Also available as oral solution. https://t.co/dZ21V2cKwR https://t.co/QADVP2w3Tz

Review of the Scleroderma spectrum disorders (full-read) https://t.co/Z7cUrVeGRR https://t.co/VkYag0uZnX https://t.co/QK6bfcYBoF

Full read review on Psoriasis Flares; risks: - mechanical stress - infections -dysbiosis -drugs (Lithium, B-blockers, HCQ, tetracyclines, ACEi, IFN) - environment(smoking, obesity) -lifestyle - stress - hormonal/metabolic https://t.co/WfCzcG9XNM https://t.co/ZNeKxjtHSA https://t.co/sJDoSfFOL4

NEJM Images - Polyarteritis Nodosa. 62 yoM with myalgias, wt loss, numbness, negative ANCA & HBV. Abdominal angiography shows multiple aneurysms. https://t.co/ONiQ82HWtj https://t.co/WIgOEywqAS https://t.co/ftjobeQDcL

Is there an Increasing Risk for Tick-Borne Disease ? JAMA article purports this to be so..... I think not - not unless you live in endemic areas. Other wise these still are rare, rare or misdiagnosis based on serologic inaccuracies - just my opinion.https://t.co/Sfu2UlLlwH https://t.co/z5TpNrDCWD