Systemic sclerosis sine scleroderma in children is more aggressive than in adults. 18 juvenile vs 38 adults - ssJSSc more female (39% vs 89%), more digital pitting scars/ulcers (35 vs 10.5%), Pulm (50 vs 24) & CV (50 vs 3%); w/ more deaths https://t.co/l4f5bH1IX1 https://t.co/viQcD3tN9V

Australian study of informal caregivers (not iworking) of arthritis pts shows excess cose of $388 million (in 2015), expected to increase to $576.9 million by 2030. Informal caregivers less likely to work, due to the demands & duties of their caregiving https://t.co/Gw1eIBN6WW https://t.co/h1TY0BtaSE

Disjointed incomplete arthritis care! 82 arthritis pts w/ new complaints surveyed; 29% went to the ED (1/3 repeat visit) for arthritis flare. Only 26% referred to a rheumatologist of which 38% were unable to do so in the time frame suggested. https://t.co/f3RbhdKL8u https://t.co/C1iRsQoiAJ

Canadian study of 44,438 older adults (age 76) w/ gout found only 52% reached serum uric acid (SUA) target w/in 12-mos, improving from 45% (2010) to 61% (2019). ULT adherence was 55%, also improved annually. Only 3.5% Rx by Rheumatologist! https://t.co/vAc8myxiRm https://t.co/gcMz379iPH

Review of 31 FDA Rheum drug approvals betw 1995-2021 showed patient-reported outcomes seldom reported or published. Despite meeting MCID (57%) & significance (85%), 1/3 PROs not reported & 10% remained unpublished (4yrs later) https://t.co/pvGhTxlP03 https://t.co/t3VEHw7FJv

FDA has approved upadacitinib (Rinvoq), for use in pediatric patients (age >2 years) w/ active polyarticular juvenile idiopathic arthritis (pJIA) & psoriatic arthritis (PsA), after inadequate resp/intolerance to TNFi. Also available as oral solution. https://t.co/lGvIHb8wfZ https://t.co/8BiTnTNJzO

Review of the Scleroderma spectrum disorders (full-read) https://t.co/xaIxf8q0Tj https://t.co/kxFiQTqKqV

Boxed Warnings in Derm: - Topical Calcineurin inhib (atopic dermatitis): rare risk of cancer - IL-17 Inhibitors (PSO, PsA): exacerbation of IBD (38 RCTs: only 12/16,690 new IBD case - Psoriasis and suicidality: suicide risk same w/ or without treatments https://t.co/HsjO78NtjP https://t.co/v9Pys8RwcH

Cohort study of 25 315 women followed 25 years shows adherence to the Mediterranean diet associated with a 23% reduced all-cause mortality - explained by lipids, inflammation markers and BMI; more than cholesterol or glycemic measures https://t.co/kgj18lG12G https://t.co/NN2FlPSngW

TriNetX US claims study of 7580 RA pts Rx w/ tofacitinib or adalimumab found Tofa signif. more likely to cause dyslipidemia (HR 1.250), but no difference betw TOFA & ADA in MACE (HR 0.995; 0.76–1.3) or all-cause mortality (HR 1.4; 0.89–2.2) https://t.co/83CGng2R9e https://t.co/QfD4ePuTER

ACR’s Run at Goliath (PCPs) (5.31.2024) The ACR (and Cush) address their new website designed to educate PCPs and APPs - what do you think? https://t.co/DQOkhowU0b https://t.co/MK9aVe7Yaf

We are covering #EULAR24! We'll be sharing recaps, videos, and more. https://t.co/7ehREq5gnl https://t.co/ao2LzcFxrt