Tweets
Understudied neurological involvement 🧠in RA
in pts > 65 vs. matched HC
-larger lateral cerebral ventricles
-brain atrophy
-shrinkage of thalamus + frontal cortical regions
-association w/ clinical depression
@RheumNow POS0148 #EULAR2024 https://t.co/2mV4qGyBtW
Aurelie Najm @AurelieRheumo ( View Tweet )
1 year 10 months ago
BARI reduces nociplastic pain, small cohort RA n=13
-wk 12 ACR FM score 14 vs 10.5 p=0.03
-fMRI data: reduction connectivity between DMN and posterior insula & between IPL & anterior/middle insular regions
Directs mechanims yet to be investigated
@RheumNow POS0310 #EULAR2024 https://t.co/jGgvS5qqV6
Aurelie Najm @AurelieRheumo ( View Tweet )
1 year 10 months ago
Is RA always preceded by clinically suspect arthralgia? Cohort 650+ pts CSA = 83 pts no CSA = 616 pts
Pts w/ no CSA: -older -more frequent acute onset of symptoms -higher SJC -increased CRP -less ACPA+ No sure how accounted for memory bias
#EULAR2024 @RheumNow POS1030 https://t.co/dJeN41ax5P
Aurelie Najm @AurelieRheumo ( View Tweet )
1 year 10 months ago
9 new MOAs in SLE to review - anti-cd38, cd40, ubiquitin ligase, tyk2, toll 7/8, baff-r, blyss/april, CAR-T, glycosylated cd20 @rheumnow #EULAR2024
Peter Nash @drpnash ( View Tweet )
1 year 10 months ago
EFFICACY AND SAFETY OUTCOMES OF TAK-279, A SELECTIVE ORAL TYROSINE KINASE 2 (TYK2) INHIBITOR, FROM A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED PHASE 2B TRIAL IN PATIENTS WITH ACTIVE PSORIATIC ARTHRITIS - smells tastes & looks like a Tyk2 - acne signal? @rheumnow #EULAR2024
Peter Nash @drpnash ( View Tweet )
1 year 10 months ago
EFFECTIVENESS & COST-EFFECTIVENESS OF PATIENT-INITIATED FOLLOW-UP SUPPORTED BY ASYNCHRONOUS TELEMONITORING IN SPA (TeleSpA-STUDY): PRAGMATIC MULTICENTRE RVT cost effective but no one will ever be examined again especially for pathology outside joints! @rheumnow #EULAR2024
Peter Nash @drpnash ( View Tweet )
1 year 10 months ago
FAPI PET/CT entheseal & synovial fibroblast activation predicts PsA in high risk PsO better than MUS @RheumNow #EULAR2024 https://t.co/uqmEvMg9WN
Peter Nash @drpnash ( View Tweet )
1 year 10 months ago
more evidence in PsA - switch MOA rather than cycle within class failed first TNF @RheumNow #EULAR2024 https://t.co/hf2UB5MXEy
Peter Nash @drpnash ( View Tweet )
1 year 10 months ago
opposing point of view especially in males at 3 years !@RheumNow #EULAR2024 https://t.co/CXxIScQbFD
Peter Nash @drpnash ( View Tweet )
1 year 10 months ago
#wasup in #GCA?
#upadacitinib +RCT in #temporal #arteritis LBA0001
Residual #inflammation in 1/3 of pts at 6 mo #Rx w #TCZ on repeat TA Bx
OP0621
#PMR cases
#Leflunomide beats #MTX for
#pred sparing
⬇️relapses
But MTX dose was low
POS0280
#EULAR2024 @RheumNow @eular_org
Janet Pope @Janetbirdope ( View Tweet )
1 year 10 months ago
New #JAKi #disease #results
#Baricitinib in #alopecia #areata esp 4mg/d
#Upadacitinib in Crohn’s
#Upa in #polyarticular #JIA & kid #PsA
+RCT of UPA in #GCA
Awaiting results of #SLE
With #deucravicitinib & UPA #RCTs
#EULAR2024 @eular_org @RheumNow
Janet Pope @Janetbirdope ( View Tweet )
1 year 10 months ago
#Behcet’s #syndrome is increasing in the UK
? ⬆️ Detection
? Changing population demographics
? Other reasons
Poster discussion POS0258
#EULAR2024 @RheumNow @eular_org
@Pr1yankaC https://t.co/SEzmJnFMhM
Links:
Janet Pope @Janetbirdope ( View Tweet )
1 year 10 months ago
