Tweets
ARCTIC Rewind: Can You Taper DMARDs with Remission?
https://t.co/5Mkdyt4DIK https://t.co/0Z2gVpjIgX
Dr. John Cush @RheumNow ( View Tweet )
1 year 9 months ago
Very late onset Lupus (>60) is less female, less arthritis/dz activity, lower dsDNA, C3, SSA, SSB and ANA but more Sjogrens & RA? Single clinic study of 845 SLE - jSLE (<18), aSLE (18-49), lSLE (50-60), and vlSLE (>60). vlSLE had lowest survival (20yrs) https://t.co/i3nQPVGYeP https://t.co/fiJe1g3AI3
Dr. John Cush @RheumNow ( View Tweet )
1 year 9 months ago
TLR Antagonist in Lupus
An investigational TLR ) antagonist was effective in reducing biomarkers and clinical symptoms of SLE in a pilot trial, evidence that the innate immune system may hold the key to lupus pathophysiology.
https://t.co/QSX3fRXRLs https://t.co/jt5nVer2ZQ
Dr. John Cush @RheumNow ( View Tweet )
1 year 9 months ago
ICYMI: What are the Early Stages of Lupus?
https://t.co/2ACuh2WirF
Dr. John Cush @RheumNow ( View Tweet )
1 year 9 months ago
Mexican study 202 #SLE pts shows 89 (45.1%) were hospitalized; their profile was they were younger, shorter Dz duration, higher disease activity scores (SLEDAI), and more damage. Hosp were for Dz activity (61%), Renal Dz, infection, drug toxicity (5.6%)https://t.co/3TKb1ck18V https://t.co/om2R3kfpFY
Dr. John Cush @RheumNow ( View Tweet )
1 year 9 months ago
Study of f 234 AAV pts. 85 (36%) developed diffuse alveolar haemorrhage. Independent predictors of DAH: 1) Age [OR=1.037); 2) PLT # [OR=0.996]; 3) ESR [OR=1.028]; 4) HgB [OR=0.978]; 5) hematuria [OR=3.77] https://t.co/eKOu5PHs4R https://t.co/mGwLAVJhAN
Dr. John Cush @RheumNow ( View Tweet )
1 year 9 months ago
“50% of pts with lupus nephritis are asymptomatic . You have to have a degree of kidney damage before you have proteinuria. Proteinuria does not correlate with intrarenal activity.” – Dr. A Fava #RNL2024 @rheumnow https://t.co/UOC8MZDM8N
Links:
Dr. John Cush @RheumNow ( View Tweet )
1 year 9 months ago
Danish registry study shows positive association between maternal autoimmune Dz & childhood cancer. AID assoc w/ all child CA (OR=1.25), ALL (1.52), Burkitts (2.69), CNS tumors (1.45). RA mothers AID had higher risk of all cancers (OR=2.1) https://t.co/EYHyHzOboc https://t.co/FNRrvySI8P
Dr. John Cush @RheumNow ( View Tweet )
1 year 9 months ago
Dr. Gabalawy: "How do you know what disease patients will develop in this preclinical autoimmunity state?"
@drdavidkarp ""it's like when weeds pop up in a garden, it's random ...if ACPA Ab pops up, you might have RA, if it's dsDNA, maybe lupus."" #RNL2024 https://t.co/kDkDaDRP8X
Links:
Dr. John Cush @RheumNow ( View Tweet )
1 year 9 months ago
Low urinary IL16 levels at 12 months predicts kidney survival at 3 years better than proteinuria - @Andreafava @rheumnow #RNL2024 https://t.co/4GLmJQr46C
Links:
Dr. John Cush @RheumNow ( View Tweet )
1 year 9 months ago
Rheum Chapter Notes
Dr. Jack Cush reviews this past week’s news and journal articles from https://t.co/V10S4oVFsv.
https://t.co/m6pkmYeiAl https://t.co/3cr3KwV1CP
Dr. John Cush @RheumNow ( View Tweet )
1 year 9 months ago
UK Early Inflammatory Arthritis Audit of 20,060 RA pts (~12k on MTX; 5K csDMARD; ~2.5K no DMARD). Serious infections (SIE) hosp rate was 3.19/100PY, death 0.1/100PY. SIE risk incr w/ age, smoking, Hi DAS28 & HAQ. 1 unit DAS28, SI risk increased by 8% https://t.co/OrNh8oYE3y https://t.co/DqbeibNMbp
Dr. John Cush @RheumNow ( View Tweet )
1 year 9 months ago
