Sniffles & Arthritis (3.1.2024) Dr. Cush reviews the news and journal reports from the past week on RheumNow. Are these associations with infection, biomarkers and weather real or imaginary? Linked or luck? Causal or casual? You decide.... https://t.co/xqoaycXeIm https://t.co/zQdXoj680T

Head to Toe, There’s No Place These Cells Won’t Go Biana Modilevsky, DO presents her poster at RWCS 2024. https://t.co/AEd0gk6THj https://t.co/3Rsv07WwA9

Cross-sectional multicenter study of 500 ax-SpA pts on biologics found 25% w/ Irritable Bowel Syndrome (IBS) that was linked to being Female gender, unemployed, higher BASDAI & BASFI, multiple biologics, FM , anxiety, depression & lower physical activity. https://t.co/RSKVcXZwLt https://t.co/RGsw3fHr3H

An assessment of screening for latent tuberculosis in patients initiating b/tsDMARD therapy found over 1 in 3 new b/tsDMARD users did not receive TB screening within recommended time window, as well as variation in screening between drug classes In AC&R https://t.co/MGsWNZCiPW https://t.co/QRFq1lqWt6

Machine learning of 701 Anti-Synthetase (Anti-Jo1, -PL7, -PL12, -EJ) identifies 3 Endotypes,independent Ab specificity #1 (24%) w/ RP-ILD & high mortality #2 (14%) dermatomyositis, intermediate prognosis #3 (62%) arthritis & mechanics hands, good prognosis https://t.co/y9LMCfMIgN https://t.co/y0MbYlbbrV

Many with PsA Fail to Achieve Minimal Disease Activity Despite the availability of numerous advanced therapies for PsA, there remains a substantial burden and unmet need for improved therapies, according to a newly published Canadian study https://t.co/OUb3bKo98v https://t.co/FDCBcdyIBm

Polyarteritis Nodosa (PAN): Clinical Features and Outcomes A multinational study of PAN through the international GLOBAL-PAN network shows PAN to be a complex, multisystem disorder with a high risk of relapse and low risk of death (11% at 10 years). https://t.co/jNNATtKTxA https://t.co/j5o6qTL2zM

Australian study shows self-reported difficulties w/ ambulation (limited<=1 km) had a higher risk of hip and spinal fractures (32% to 219% more)/ Included 239 000 adults >45 yrs https://t.co/5rIkDOK69u https://t.co/iJ8o0dlGlS

Neonatal Fc receptor mAb (lowers Igs) development: 2021 FDA approved efgartigimod (Vyvgart) for myasthenia gravis 2023 FDA approved rozanolixizumab (Rystiggo) for MG 2023 nipocalimab promising efficacy in RA, Sjogrens, hemolytic anemia, MG INTERESTING? https://t.co/HB1fJet3Bo https://t.co/OBrd2Y3nye

Sinusitis Linked to 40% Heightened Risk of Rheumatic Disease The common inflammatory condition sinusitis is linked to a 40% heightened risk of a subsequent diagnosis of rheumatic disease, finds research published in the open access journal RMD Open. https://t.co/hMlKxIDvlb https://t.co/eNEMuH4Tdc

Metabolic signature for fibromyalgia? Study of 54 FM & 31 controls w/ Machine learning to identify 13 metabolic markers that predicted FM w/ 79% accuracy; levels of 5-hydroxyindole-3-acetic acid & glutamine correlated w/ fatigue. https://t.co/GBTh7UGn1O https://t.co/jlwVAbdIIF