Outcomes of Acute, Subacute and Persistent Low Back Pain Low back pain is a major cause of disability around the globe, with more than 570 million people affected. https://t.co/aIR110aEr0 https://t.co/tKPp0Un68H

Is non-alcoholic fatty liver dz assoc w/ osteoarthritis? Study of 2633 pts - 317 (12.8%) w/ OA& 1140 NAFLD(41.5%); NAFLD was positively correlated with OA (OR = 1.72; 1.26–2.34). https://t.co/whWX2XIu3d https://t.co/sGXQYSFcH3

Wed. Jan 31st was Dr. Janet Woodcock’s last day at the US Food and Drug Administration (FDA), capping a remarkable 38-year career. A rheumatologist, Dr. Woodcock She’s has been one of the most powerful and influential drug regulators worldwide. THANKS JW! https://t.co/vVUGaknYmM https://t.co/9pV7QYH0zm

Full read, great review of JAK/STAT signaling and JAK inhibitors published in Ann Rheum Dis.-- Selectivity, efficacy and safety of JAKinibs: new evidence for a still evolving story (Authored by JAK mavens) https://t.co/dimQAy2igo https://t.co/5xh1DqjFxN

2022 EULAR Recommendations on Screening & Prophylaxis for Opportunistic Infections https://t.co/gxiEBixh47 https://t.co/piwR6rNLqd

Diet and Osteoarthritis Pain Knee osteoarthritis (OA) pain was worse with a pro-inflammatory diet, an observational study suggested. https://t.co/GHSd9SzNav https://t.co/MiCj9gE4Kj

240 consecutive estab. RA pts underwent cervical spine X-rays looking for ant. atlantoaxial subluxation (aAAS >3 mm); aAAS found in 25 (10.4%) mean interval =4.2mm. One-third had no neck pain. aAAS predicted by lower BMI, CCP, erosions & joint prostheses https://t.co/OXNbJ6aiCG https://t.co/4tNqGvfNcK

Dupilumab (IL-4/13 Inhib) may cause MSK Sxs. Study of 470 Atopic Dermatitis pts on dupilumab; 36 referred to rheum consult, 26 pts (14M/12F) had US/MRI proven enthesitis, arthritis, or tenosynovitis (16 mild, 4 severe). All responded to NSAID or DUP D/C https://t.co/S3ACOC4xUZ https://t.co/juAYbIxNZ6

Metabolic Syndrome increases RA risk. UK Biobank (369,065) study saw 4901 incident RA (12 yrs F/U). Signif hi RA risk with MetS (HR 1.22), waist circumf (1.21), incr TG (1.12), decr HDL (1.31) & hyperglycemia (1.15) - all additive. https://t.co/jN15axxTmu https://t.co/DP5bFwOB3F

Greek study finds 251/1264 #RA pts (20%) had difficult to treat RA (D2T). D2T Predictors were Younger age, fibromyalgia, OA, no change in DAS28-ESR in 1st 6mos b/ts-DMARD Rx. Mental-/pain-/metabolic-Dz contributed to LT worsening https://t.co/QIsu6yIJHO https://t.co/NyKKlyOQi1

Study of 235 newly Dx #RA patients (157 females) found that 11 pts (5%) had carpal tunnel syndrom (CTS) at the time of initial RA diagnosis. Such pts were more likey to be older, female, CCP negative and have a longer Sx duration. https://t.co/Jb3hynyqGx https://t.co/EbTvHGq5Yk

16% of patients with nr-axSpA progressed to r-axSpA within 5 years. Male sex, fulfillment of the imaging arm of the ASAS criteria, and good response to nonsteroidal anti-inflammatory drugs were predictors of radiographic progression https://t.co/2qCynSGQjv https://t.co/eogKGacpqH