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While #dupilumab can be used for #EGPA, be careful about using it in pts with high eosinophilia; don't taper steroids too rapidly if you use this drug. - Dr P Seo @rheumnow #RNL2024 https://t.co/YKQdtvCS0M
TheDaoIndex @KDAO2011 ( View Tweet )
2 years ago
Consider using IV Benralizumab (also an IL5 inhibitor) for #EGPA in pts where insurance won't approve SQ mepolizumab - Dr. P Seo #RNL2024 @rheumnow https://t.co/VFE76Uzb2S
TheDaoIndex @KDAO2011 ( View Tweet )
2 years ago
EGPA - Peanut butter and Jelly @philseo Respiratory symptoms and systemic disease Respiratory: non-systemic (inhalers, steroids, irrigation) IL-5 inhibs Non-respiratory: eosinophilic (myocarditis, urticaria, EE), vasculitis (MM, GN, DAH, purpura, arthralgias) #RNL2024 @RheumNow https://t.co/KTlvZ1cnfH
Eric Dein @ericdeinmd ( View Tweet )
2 years ago
"EGPA is a lot like peanut butter and jelly, two separate things showing up at the same time (in terms of respiratory and systemic manifestations.)" Dr. @philseo at #RNL2024 @RheumNow https://t.co/l0WgG1caN0
Dr. Rachel Tate @uptoTate ( View Tweet )
2 years ago
“Patients with EGPA are like peanut butter and jelly … 2 different manifestations: respiratory manifestations and systemic manifestations” - Dr. P Seo with lunch on his mind. #RNL2024 @rheumnow https://t.co/y7SLEG9qRt
TheDaoIndex @KDAO2011 ( View Tweet )
2 years ago
Dr. P Seo's Pearls for #Vasculitis: 1. Weekly or q2weeks SC TCZ is fine for newly diagnosed patients, but if pts relapse, use weekly TCZ. 2. oral steroids perform fine (no need to do IV pulse) even in pts with vision changes 3. taper steroids over 3-4 months @rheumnow #RNL2024

TheDaoIndex @KDAO2011 ( View Tweet )

2 years ago
The great unknown with tocilizumab in GCA, do you stop, how do you stop, etc. @philseo approach. I'm not as brave! Usually park at every other week dosing @RheumNow #RNL2024 https://t.co/y7mg57mWND
Richard Conway @RichardPAConway ( View Tweet )
2 years ago
Do you have GCA patients on low dose prednisone? Feel reassured. Dr. @philseo provides data showing that low dose prednisone may be helpful in remission maintenance. #RNL2024 @RheumNow https://t.co/oyOsczfkfv
Dr. Rachel Tate @uptoTate ( View Tweet )
2 years ago
Interesting nuance from @philseo re tocilizumab in GCA. For new onset disease, it may be appropriate to use every other week tocilizumab @RheumNow #RNL2024 https://t.co/moCvpQSkq0
Richard Conway @RichardPAConway ( View Tweet )
2 years ago
Do you need to pulse steroids in GCA? ACR 2022 abstract#0459 data says oral only may be sufficient Oral vs IV MP - p=0.621 Still favor IV in severe cases @philseo #RNL2024 @RheumNow

Eric Dein @ericdeinmd ( View Tweet )

2 years ago
Amaurosis fugax is not the only vision symptoms to assess in patients with #GCA. Blue vision, double vision (if patients have to look at you in a side gaze prevent double vision) may also be present - Dr. P Seo @rheumnow #RNL2024 https://t.co/AhQnOJF7fa
TheDaoIndex @KDAO2011 ( View Tweet )
2 years ago
#RNL2024 @RheumNow @philseo: I now give Tociliizumab for nearly all patients with GCA GiACTA shows we weren't doing well enough with steroid monotherapy GiACTA shows dosing frequency does not make a big difference in new diagnosis, but makes a difference in relapsing disease https://t.co/JBgUQtZSAr
Eric Dein @ericdeinmd ( View Tweet )
2 years ago
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