Full read review of IL-18 binding protein, natural antagonist of IL-18 . https://t.co/cGVQeyrXd9 https://t.co/XRhk9Ut0TN

Biology and Rx of Lupus Flares https://t.co/VlaI1PK8X8 https://t.co/oFXqGUvL4b

Biomarker Predictors of Osteoarthritis Science Advances has reported that Duke University researchers have validated a biomarkers of osteoarthritis that may be identified 2 years before the appearance of radiographic OA. S https://t.co/T9XQ3x9yc2 https://t.co/HdwbXR1nDX

ARCTIC Rewind: Can You Taper DMARDs with Remission? https://t.co/5Mkdyt4DIK https://t.co/0Z2gVpjIgX

Very late onset Lupus (>60) is less female, less arthritis/dz activity, lower dsDNA, C3, SSA, SSB and ANA but more Sjogrens & RA? Single clinic study of 845 SLE - jSLE (<18), aSLE (18-49), lSLE (50-60), and vlSLE (>60). vlSLE had lowest survival (20yrs) https://t.co/i3nQPVGYeP https://t.co/fiJe1g3AI3

TLR Antagonist in Lupus An investigational TLR ) antagonist was effective in reducing biomarkers and clinical symptoms of SLE in a pilot trial, evidence that the innate immune system may hold the key to lupus pathophysiology. https://t.co/QSX3fRXRLs https://t.co/jt5nVer2ZQ

Mexican study 202 #SLE pts shows 89 (45.1%) were hospitalized; their profile was they were younger, shorter Dz duration, higher disease activity scores (SLEDAI), and more damage. Hosp were for Dz activity (61%), Renal Dz, infection, drug toxicity (5.6%)https://t.co/3TKb1ck18V https://t.co/om2R3kfpFY

Study of f 234 AAV pts. 85 (36%) developed diffuse alveolar haemorrhage. Independent predictors of DAH: 1) Age [OR=1.037); 2) PLT # [OR=0.996]; 3) ESR [OR=1.028]; 4) HgB [OR=0.978]; 5) hematuria [OR=3.77] https://t.co/eKOu5PHs4R https://t.co/mGwLAVJhAN

Danish registry study shows positive association between maternal autoimmune Dz & childhood cancer. AID assoc w/ all child CA (OR=1.25), ALL (1.52), Burkitts (2.69), CNS tumors (1.45). RA mothers AID had higher risk of all cancers (OR=2.1) https://t.co/EYHyHzOboc https://t.co/FNRrvySI8P