Canadian OBRI study in 692 RA pts shows pts treated w/ triple DMARD (MSH) stayed on Rx longer (15 mos) compared to MTX+LEF (9.6 mos); not significant but MTX/SSZ/HCQ had signif lower DAS28 @ 6 mos (3.4 vs 3.9) & at 12 mos (3.2 vs 3.5, p=0.0005) https://t.co/ieHeXvgj3n https://t.co/MEMA1nrUpy

Join us 4/16 for Tuesday Night Rheumatology at 6:30pm ET. This week we'll be focusing on Vasculitis Mavens with: Vasculitis & Pregnancy - Catherine Sims, MD GPA Management in 2024 - Anisha Dua, MD, MPH Treat to Target in Vasculitis - Philip Seo, MD https://t.co/6IaCdCodGf https://t.co/HlZ8OiZWc4

JAMA: SLE Review Drs.Siegel & Sammaritano (from HSS in NYC) published an impressive overview of SLE) in JAMA. This timely, well-written review covers the many complexities of this multi-organ disorder that affects nearly 3.4 million people worldwide. https://t.co/byr1hRA6rV https://t.co/wZeIdfTlH0

Pearl: Patients with persistent TMJ pain are more likely to have fibromyalgia than inflammatory or degenerative arthritis (as the underlying cause of their chronic pain) https://t.co/G43rxKVHus https://t.co/4mCu7b0PGn

IL-1 recept accessory protein (IL1RAP) shown to block mediators (IL-1, IL33, IL36) that may drive systemic sclerosis. In vitro, IL1RAP inhibited fibroblasts and endothelial cells; in mouse models of SSc anti-IL1RAP decr dermal & pulmonary fibrosis. https://t.co/6YE02P4rjR https://t.co/mzw7t88Jzl

SLE in JAMA (authored by Drs Siegel & Sammaritano at HSS), impressive, full-read review, Covers: - Presentations: skin, Jts, brain, heme, etc - Treatments - Prognosis - Complications: CV, infx, CA - FAQs https://t.co/7WHYK3DgIf https://t.co/pC2MSCpn52

Polycyclic Aromatic Hydrocarbons Increase Lupus Risk A case-controlled study shows environmental exposure to polycyclic aromatic hydrocarbons (PAH) may increase the risk of developing systemic lupus erythematosus (SLE). https://t.co/AuYazGtamr https://t.co/S96LAuGtba

Join us 4/16 for Tuesday Night Rheumatology at 6:30pm ET. This week we'll be focusing on Vasculitis Mavens with: Vasculitis & Pregnancy - Catherine Sims, MD GPA Management in 2024 - Anisha Dua, MD, MPH Treat to Target in Vasculitis - Philip Seo, MD https://t.co/5tvMJ5P2FC https://t.co/sk8Te3iEIy

Best Imaging in Giant Cell Arteritis - US, PET, MRI? Imaging is often instrumental in diagnosing and staging patients diagnosed with giant cell arteritis (GCA). https://t.co/LXVB6cHDfO https://t.co/ArLNdEPuVx

This study examined the risk of neuroinflammatory disease after initiation of b/tsDMARDs Overall risk of neuroinflammatory events among new users of TNF inhibitors did not differ substantially as compared to new users of other b/tsDMARDs In AC&R https://t.co/8rGgZmpq9c https://t.co/5gxuWBctBL

Korean National Insurance claims study (2010-18) of NSAID use and CV events found among 19,775 RA pts (F/U 98290 PYs); there were 1663 cases of CV evens. Increasing NSAID doses incr incident CVD(adjHR 1.10); including CVA (aHR 1.09). CHF (aHR 1.12) https://t.co/mdRKYMQq1s https://t.co/36i2KT4j5A

LEGISLATION: In the USA, betw 2019-2023, 13 policies introduced in 7 different states to encourage nonpharmatologic measures for pain management (PT, CBT, acupuncture, chiropractic, etc). Only 2 were enacted, 3 in progress, 1 vetoed, 7 failed https://t.co/hYK3pRHG5D https://t.co/28PHVUiTD3