649 # RA pts (291 ACPA+) from the Leiden Early Arthritis Clinic shows Disease activity incr by: - Obesity: + 0.32 higher DAS - Obese + ACPA+: + 0.43 DAS - ACPA+ RA: SJC incr 60%, TJC 55%, CRP + 3.7 mg/L https://t.co/WH0tpybe4a https://t.co/jkgDLQdfRH

Determinants of Gout Flares Approximately 12 million US adults in the US have gout. Two recent literature reports highlight contributors to gout flares. https://t.co/xAUyBsJVz9 https://t.co/bEo10XJ9qv

J&J announced the results of Phase 2 DAHLIAS study of nipocalimab in Sjögren’s; w/ a signif reduction in clinESSDAI at week 24 vs placebo. Nipocalimab is an investigational anti-FcRn treatment being studied in RA, & myasthenia gravis https://t.co/L7WNtdii8N https://t.co/Ro6UoPT2fR

Acute CPPD at significantly higher risk of fractures. 1148 acute CPPD pts matched to 3730 comparators(mean 73 yrs old); Steroids and OP more in CPPD pts. Fx risk was twice as high in the acute CPPD pts (HR 1.8;1.3, 2.3). Fx risk highest forwrist (HR, 3.6) https://t.co/25EOzXI0sH https://t.co/c1Xiq8TaUP

Racial and Ethnic Determinants of Psoriatic Arthritis A study from a large metropolitan registry of psoriatic arthritis (PsA) patients showed several racial and/or ethnic groups are underrepresented and demonstrate differences in disease activity. https://t.co/lHQxchTSyU https://t.co/AcXcpvuGI8

Join our experts, Drs Liebowitz and Mehta, as they provide insights on the differential diagnosis and management concepts in autoinflammatory diseases. https://t.co/KooVTScHvd https://t.co/RemKaT5ROn

Autoimmune disease and pregnancy For many aspiring mothers with autoimmune disease, pregnancy can be daunting and full of unknowns. I https://t.co/HtXEH3S0CQ https://t.co/G0fYlgble0

Danish registries study shows maternal Autoimmune Dzs (all) were assoc w/ incr risk of childhood cancers (OR=1.25, 95% CI 1.06, 1.47), acute lymphoblastic leukemia (OR =1.52), Burkitt lymphoma (OR=2.6) & CNS tumors (OR=1.45); same seen for RA mothers https://t.co/VCgwQRSLEY https://t.co/OmB8XPH7n7

Study of 78 #RA pts(83% CCP+) showed signif. discordance between office visit DAS scores & telephone eval by RAPID3 (w/in 2 wks of F2F visit). By RAPID3, 27% were in remission, vs F2F DAS-CRP 71%) or DAS-ESR (33%) kappa= 0.48 (mod) & 0.14 (low agreement) https://t.co/DsgR0aMUGf https://t.co/smnFe13m5W

Metanalysis of 14 RCTs (602,760 pts) showed a higher risk of venous thromboembolic events in #RA- w/ significant 57% increased risk compared to general population: VTE (RR 1.57) DVT (RR 1.58) PE (RR 1.57) https://t.co/vCCMe46NNP https://t.co/c204ga4v01

Leaving Academia Dr. Jack Cush reviews the news and journal reports from the past week on https://t.co/V10S4oVFsv. This week we discuss hipsters undergoing hip replacement, pregnancy outcomes in RA and the future of academic clinicians. https://t.co/cuENQxlSOt https://t.co/olMihVm4bU

SeXXist Reason for More Women with Autoimmune Disease Somewhere between 24 and 50 million Americans have an autoimmune disease, a condition in which the immune system attacks our own tissues. As many as 4 out of 5 of those people are women. https://t.co/RO7k5BGXci https://t.co/z5YdE59gTq