Very cool meta analysis of IL17i RCTs in PsA No change in MACE in DMARD naieve pts initiating IL17i across RCTs A skosh underpowered but worthwhile question & useful data @RheumNow #ACR23 Abstr2254 https://t.co/ZN8QYgSA1A

A#2297 #ACR23 @RheumNow Baseline IFNα predicts complete response at 2 yrs in LN HIgh IFNα: incr risk of 2+ renal flare Increase of 1 unit of IFNα incr risk of 2+ flares by 35% & risk of decr GFR IFNα cutoff 0.6 for 2+ flare, 1.3 for progr to eGFR <15 AUC 0.6 (weak predictor) https://t.co/FKeDJVNyYj

In this older grp of pts w/ chronic LBP, significant overlaps of deg & inflamm features on spinal imaging of DC, DISH & axSpA pts were seen Also, +comorbids: HTN in DC; DM in DISH; smoking in axSpA THM? DC & DISH are also axSpA mimics #ACR23 ABST1862 @Rheumnow @rheumarhyme https://t.co/uNIwRchF1g

HCQ improves complements A#2327 #ACR23 @RheumNow Petri @jhrheumatology @andreafava Pts w/ low complement & low HCQ levels In pts who increased HCQ WB level >50 ng/mL, incr in mean C3 (p=0.02) v HCQ that did not incr More nml C4 levels (p=.003) and incr mean C4 (p=.004) on HCQ https://t.co/J7PIuaRTO8

HCQ Discontinuation A#2343 #ACR23 @RheumNow 42 pts d/c HCQ 19% flared in past yr before d/c D/c reasons: retina tox 57%, self-dc 17%, other eye issue 12% 26% flare in yr after d/c - strongest ass for flare: mean C3, dsDNA+ at index visit https://t.co/d4TqneS46u

Another day, another bimekizumab (IL17i) study Across 2 trials, improved PsA specific QOL ("PsAID") metrics Nice to see focus on PROs & I always love a good spidergram @RheumNow #ACR23 Absr2249 https://t.co/dsLXstPzt2

All of us need to remind each other to take care of yourself! Some tips from Dr. Whitney Marvin - exercise, date night, talking to a friend - take breaks, mindfulness - eating away from computer (as I type this on my desk, next to my lunch) @RheumNow #ACR23 https://t.co/UmmDqXRECN

Will postpartum BME ⏩axSpA-like structural lesions? Study by Varkas et al show there was no significant dev't of axSpA-like lesions on MRI in postpartum women 5 yrs after delivery. Postpartum BME likely sec to transient mech stress-induced SI BME #ACR23 ABST1892 @RheumNow https://t.co/KJ3DngmkbI

Always refreshing to hear from another specialist's point of view Cardiologist @Bweber04 on CVD and rheumatologic diseases Increased risk of death, MI and HF exacerbation in our pt population Increased all cause mortality @RheumNow #ACR23 https://t.co/yOkPOmxU4N

@Bweber04 on recurrent pericarditis especially some seen in our lupus population IL-1 inhibition with Rilonacept really redefining treatment success and altering the typical treatment algorithm @RheumNow #ACR23 https://t.co/Ey1DN8eSXT